Patents by Inventor Piera Fonte

Piera Fonte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9862740
    Abstract: The present invention relates to a process for obtaining Tiacumicin B with a well defined crystal habit and particle size. The process according to the invention comprises repeating cycles of heating and cooling under controlled conditions of temperature and stirring.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: January 9, 2018
    Assignee: OLON S.P.A.
    Inventors: Piera Fonte, Giovanni Lazzari
  • Publication number: 20170057988
    Abstract: The present invention relates to a process for obtaining Tiacumicin B with a well defmed crystal habit and particle size. The process according to the invention comprises repeating cycles of heating and cooling under controlled conditions of temperature and stirring.
    Type: Application
    Filed: February 25, 2014
    Publication date: March 2, 2017
    Inventors: Piera Fonte, Giovanni Lazzari
  • Patent number: 9045515
    Abstract: The present invention relates to an improved process for the purification of tiacumicin B. Specifically, the invention relates to a simplified, optimised process for the purification of tiacumicin B from a fermentation broth, using chromatography techniques. In particular, the invention relates to a method for purifying tiacumicin B which comprises subjecting a liquid containing tiacumicin B to at least one hydrophobic interaction chromatography step. The process according to the invention is simpler than the processes according to the prior art, and can easily be used on a large scale for commercial production.
    Type: Grant
    Filed: April 3, 2013
    Date of Patent: June 2, 2015
    Assignee: OLON S.P.A.
    Inventors: Piera Fonte, Giovanni Lazzari
  • Publication number: 20130267692
    Abstract: The present invention relates to an improved process for the purification of tiacumicin B. Specifically, the invention relates to a simplified, optimised process for the purification of tiacumicin B from a fermentation broth, using chromatography techniques. In particular, the invention relates to a method for purifying tiacumicin B which comprises subjecting a liquid containing tiacumicin B to at least one hydrophobic interaction chromatography step. The process according to the invention is simpler than the processes according to the prior art, and can easily be used on a large scale for commercial production.
    Type: Application
    Filed: April 3, 2013
    Publication date: October 10, 2013
    Applicant: OLON S.p.A.
    Inventors: Piera Fonte, Giovanni Lazzari
  • Patent number: 7019140
    Abstract: A process for the synthesis of pergolide (Formula (I)) (D-6-n-propyl-8?methylmercaptomethylergo line) from acid 9,10-dihydrolysergic is herein disclosed. The process can be carried out without isolating most intermediates and is particularly convenient both from the yield and safety standpoint.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: March 28, 2006
    Assignee: Antibioticos S.p.A.
    Inventors: Walter Cabri, Paolo Paissoni, Jacopo Roletto, Piera Fonte, Sara Olmo
  • Publication number: 20050124812
    Abstract: A process for the synthesis of pergolide (Formula (1)) (D-6-n-propyl-8?methylmercaptomethylergo line) from acid 9,10-dihydrolysergic is herein disclosed. The process can be carried out without isolating most intermediates and is particularly convenient both from the yield and safety standpoint. Moreover, pergolide thereby obtained is highly pure and can be conveniently transformed into pergolide mesylate.
    Type: Application
    Filed: March 10, 2003
    Publication date: June 9, 2005
    Inventors: Walter Cabri, Paolo Paissoni, Jacopo Roletto, Piera Fonte, Sara Olmo