Patents by Inventor Piere Marggraf-Rogalla

Piere Marggraf-Rogalla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION AND METHODS FOR HYBRIDIZATION
    Publication number: 20240060120
    Abstract: The present invention relates to a composition for use in hybridization, the composition comprising: (a) at least one hybridization probe (“component (a)”); (b) at least one polar protic or polar aprotic solvent (“component (b)”) having a cyclic molecule structure; and (c) at least one carboxylic acid amide and/or salts thereof (“component (c)”), in an amount of more than 10 vol %, based on the composition. The invention furthermore relates to a use of this composition, and to methods for detecting nucleic acids and/or chromosomal aberrations in a biological sample by way of hybridization, using the composition.
    Type: Application
    Filed: October 30, 2023
    Publication date: February 22, 2024
    Inventors: Piere Marggraf-Rogalla, Sven Hauke
  • METHOD FOR DETECTING CHROMOSOMAL ABNORMALITIES
    Publication number: 20210371913
    Abstract: The invention relates to a method for identifying chromosomal abnormalities, particularly structural and/or numerical chromosomal abnormalities, and preferably structural chromosomal abnormalities, using insitu hybridization by detecting chromosomes and/or DNA regions in a biological sample, preferably in one or more cell(s) and/or in one or more cell nuclei.
    Type: Application
    Filed: August 11, 2021
    Publication date: December 2, 2021
    Inventors: Piere Marggraf-Rogalla, Sven Hauke
  • Method for detecting chromosomal abnormalities
    Patent number: 11174508
    Abstract: The invention relates to a method for identifying chromosomal abnormalities, particularly structural and/or numerical chromosomal abnormalities, and preferably structural chromosomal abnormalities, using in situ hybridization by detecting chromosomes and/ or DNA regions in a biological sample, preferably in one or more cell(s) and/or in one or more cell nuclei.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: November 16, 2021
    Assignee: Zytovision GmbH
    Inventors: Piere Marggraf-Rogalla, Sven Hauke
  • METHOD FOR DETECTING CHROMOSOMAL ABNORMALITIES
    Publication number: 20180282795
    Abstract: The invention relates to a method for identifying chromosomal abnormalities, particularly structural and/or numerical chromosomal abnormalities, and preferably structural chromosomal abnormalities, using insitu hybridization by detecting chromosomes and/or DNA regions in a biological sample, preferably in one or more cell(s) and/or in one or more cell nuclei.
    Type: Application
    Filed: June 23, 2016
    Publication date: October 4, 2018
    Inventors: Piere Marggraf-Rogalla, Sven Hauke
  • COMPOSITION AND METHODS FOR HYBRIDIZATION
    Publication number: 20180237840
    Abstract: The present invention relates to a composition for use in hybridization, the composition comprising: (a) at least one hybridization probe (“component (a)”); (b) at least one polar protic or polar aprotic solvent (“component (b)”) having a cyclic molecule structure; and (c) at least one carboxylic acid amide and/or salts thereof (“component (c)”), in an amount of more than 10 vol %, based on the composition. The invention furthermore relates to a use of this composition, and to methods for detecting nucleic acids and/or chromosomal aberrations in a biological sample by way of hybridization, using the composition.
    Type: Application
    Filed: August 19, 2016
    Publication date: August 23, 2018
    Inventors: Piere Marggraf-Rogalla, Sven Hauke