Abstract: The present invention relates to obtaining isosorbide-5-mononitrate tablets, being also of retard form, which are stable in time. Such embodiment is now possible after the discovery of the stabilizing activity of the with respect to the isosorbide-5-mononitrate with which it forms a solid solution. The use of PVP is essential so that the tablets can remain stable in time: the retard effect in turn can be obtained with the use of hydroxyalkylcelluloses.

Abstract: In order to allow an adjusting of the bending tools to a given diameter of the wire being bent allowing the producing of the requisite bending radius a central mandrel which forms two bending or forming, respectively, jaws is replaceable together with a shearing tool. To this end a hollow shaft is mounted at the rear of the central mandrel, which shaft is mounted to a supporting shaft by means of a screw joint. The supporting shaft is supported in turn rotationally and can be rotated by means of a motor in order to disconnect the central mandrel. By mentioned rotation the screw joint is released. A special coupling of the shearing tool to an axially movable operating shaft allows a simultaneous disconnecting of the shearing tool together with the central mandrel. A bending mandrel is mountable at locations having various radial distances from the central mandrel.