Patents by Inventor Pierluigi FARINA

Pierluigi FARINA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical parenteral formulation containing carglumic acid
    Patent number: 11103474
    Abstract: The present invention relates to a pharmaceutical formulation suitable for parenteral administration containing carglumic acid and a buffering agent having a pKa from 5.5 to 9.0 at 25° C.; according to an embodiment, the buffering agent may have a pKa from 7.5 to 8.5, preferably a pKa of about 8.07, such as trometamol. The formulation may also contain at least one bulking agent, such as mannitol. The invention also includes a method for manufacturing a lyophilised sterile formulation by freeze-drying a water solution containing carglumic acid, a buffering agent having a pKa from 5.5 to 9.0 at 25° C., preferably from 7.5 to 8.5, and optionally a bulking agent to obtain a freeze-dried powder.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: August 31, 2021
    Assignee: RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A.
    Inventors: Fabio Berlati, Sergio Menegon, Pierluigi Farina, Diego Provvedini, Marco Barchielli, Alberto Mattei
  • PHARMACEUTICAL PARENTERAL FORMULATION CONTAINING CARGLUMIC ACID
    Publication number: 20190282526
    Abstract: The present invention relates to a pharmaceutical formulation suitable for parenteral administration containing carglumic acid and a buffering agent having a pKa from 5.5 to 9.0 at 25° C.; according to an embodiment, the buffering agent may have a pKa from 7.5 to 8.5, preferably a pKa of about 8.07, such as trometamol. The formulation may also contain at least one bulking agent, such as mannitol. The invention also includes a method for manufacturing a lyophilised sterile formulation by freeze-drying a water solution containing carglumic acid, a buffering agent having a pKa from 5.5 to 9.0 at 25° C., preferably from 7.5 to 8.5, and optionally a bulking agent to obtain a freeze-dried powder.
    Type: Application
    Filed: November 20, 2017
    Publication date: September 19, 2019
    Applicant: RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A.
    Inventors: Fabio BERLATI, Sergio MENEGON, Pierluigi FARINA, Diego PROVVEDINI, Marco BARCHIELLI, Alberto MATTEI