Patents by Inventor Pierluigi Rossetto

Pierluigi Rossetto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphs of sorafenib tosylate and sorafenib hemi-tosylate, and processes for preparation thereof
    Patent number: 8217061
    Abstract: Provided are sorafenib hemi-tosylate, polymorphs thereof, polymorphs of sorafenib tosylate, preparation thereof and pharmaceutical compositions thereof.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: July 10, 2012
    Assignee: Sicor Inc.
    Inventors: Ale{hacek over (s)} Gavenda, Alexandr Jegorov, Pierluigi Rossetto, Peter Lindsay MacDonald, Augusto Canavesi
  • CRYSTALLINE FORMS OF PALONOSETRON HYDROCHLORIDE
    Publication number: 20120122915
    Abstract: The present invention provides crystalline forms of Palonosetron hydrochloride, processes for their preparation and pharmaceutical compositions containing such crystalline forms of Palonosetron HCl.
    Type: Application
    Filed: December 23, 2011
    Publication date: May 17, 2012
    Inventors: Pierluigi ROSSETTO, Peter Lindsay MacDonald, Gaia Banfi, Csilla Nemethne Racz
  • Polymorphs of fluticasone furoate and process for preparation thereof
    Patent number: 8148353
    Abstract: Provided are polymorphs of fluticasone furoate and processes for preparation thereof.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: April 3, 2012
    Assignee: Plus Chemicals SA
    Inventors: Peter Lindsay MacDonald, Pierluigi Rossetto, Adrienne Kovacsne-Mezei, Roman Gabriel, Alexandr Jegorov, Jiri Faustmann
  • Process for the preparation of 7?-alkylated 19-norsteroids
    Patent number: 7790910
    Abstract: Processes useful in the preparation of pharmaceutical compounds such as fulvestrant and processes for the preparation of fulvestrant.
    Type: Grant
    Filed: July 27, 2005
    Date of Patent: September 7, 2010
    Assignee: Sicor Inc.
    Inventors: Peter Lindsay MacDonald, Ettore Bigatti, Pierluigi Rossetto
  • Processes for preparing palonosetron salts
    Patent number: 7737280
    Abstract: The present invention provides processes for preparing Palonosetron salts, especially, the hydrochloride salt and intermediates used to prepare Palonosetron salts.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: June 15, 2010
    Assignee: Sicor Inc.
    Inventors: Pierluigi Rossetto, Peter MacDonald, Ettore Bigatti, Gaia Banfi, Dario Tentorio
  • Polymorphs of fluticasone furoate and process for preparation thereof
    Publication number: 20100130458
    Abstract: Provided are polymorphs of fluticasone furoate and processes for preparation thereof.
    Type: Application
    Filed: August 6, 2009
    Publication date: May 27, 2010
    Inventors: Peter Lindsay Macdonald, Pierluigi Rossetto, Adrienne Kovacsne-Mezei, Roman Gabriel, Alexandr Jegorov, Jiri Faustmann
  • Process for the preparation of letrozole
    Patent number: 7705159
    Abstract: The invention provides a high-yield process for the preparation of letrozole having a high purity, without the need for removal of the 4-[1-(1,3,4-triazolyl)methyl]benzonitrile impurity at the intermediate stage. The invention also provides a process for the synthesis of letrozole in which formation of the impurity 4-[1-(1,3,4-triazolyl)methyl]benzonitrile during the first stage is minimized. In the process, a 4-(halomethyl)benzonitrile is reacted with a salt of 1H-1,2,4-triazole, reducing the formation of the impurity. Preferably, the preparation is conducted as a one-pot process.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: April 27, 2010
    Assignee: Sicor, Inc.
    Inventors: Peter Lindsay MacDonald, Ettore Bigatti, Pierluigi Rossetto, Zvi Harel
  • CRYSTALLINE FORMS OF PALONOSETRON HYDROCHLORIDE
    Publication number: 20100016593
    Abstract: The present invention provides crystalline forms of Palonosetron hydrochloride, processes for their preparation and pharmaceutical compositions containing such crystalline forms of Palonosetron HCl.
    Type: Application
    Filed: October 23, 2007
    Publication date: January 21, 2010
    Inventors: Pierluigi Rossetto, Peter Lindsay McDonald, Gaia Banfi, Csilla Nemethne Racz
  • Process for the preparation of 7alpha-alkylated 19-norsteroids
    Publication number: 20090318721
    Abstract: Processes useful in the preparation of pharmaceutical compounds such as fulvestrant and processes for the preparation of fulvestrant.
    Type: Application
    Filed: August 12, 2009
    Publication date: December 24, 2009
    Inventors: Peter Lindsay MacDonald, Ettore Bigatti, Pierluigi Rossetto
  • Process for the preparation of 7alpha-alkylated 19-norsteroids
    Publication number: 20090306417
    Abstract: Processes useful in the preparation of pharmaceutical compounds such as fulvestrant and processes for the preparation of fulvestrant.
    Type: Application
    Filed: August 12, 2009
    Publication date: December 10, 2009
    Inventors: Peter Lindsay MacDonald, Ettore Bigatti, Pierluigi Rossetto
  • Process for the preparation of sorafenib and salts thereof
    Publication number: 20090253913
    Abstract: Methods for the synthesis of the N-carbamoyl imidazole (I) and its 1:1 adduct with imidazole are provided. Methods for the preparation of these crystalline intermediates in a high state of purity are also provided. These intermediates react cleanly under mild conditions to produce sorafenib in high yield and purity, without generating difficult-to-remove impurities.
    Type: Application
    Filed: March 5, 2009
    Publication date: October 8, 2009
    Inventors: Pierluigi Rossetto, Peter Lindsay MacDonald, Augusto Canavesi
  • Process for the preparation of capecitabine
    Publication number: 20090209754
    Abstract: The present application relates to an improved process for the preparation of capecitabine.
    Type: Application
    Filed: January 5, 2009
    Publication date: August 20, 2009
    Inventors: Peter Lindsay MacDonald, Pierluigi Rossetto, Maurizio Gallina
  • POLYMORPHS OF SORAFENIB TOSYLATE AND SORAFENIB HEMI-TOSYLATE, AND PROCESSES FOR PREPARATION THEREOF
    Publication number: 20090192200
    Abstract: Provided are sorafenib hemi-tosylate, polymorphs thereof, polymorphs of sorafenib tosylate, preparation thereof and pharmaceutical compositions thereof.
    Type: Application
    Filed: January 19, 2009
    Publication date: July 30, 2009
    Inventors: Ales Gavenda, Alexandr Jegorov, Pierluigi Rossetto, Peter Lindsay MacDonald, Augusto Canavesi
  • Imatinib base, and imatinib mesylate and processes for preparation thereof
    Publication number: 20080207904
    Abstract: The present invention provides crystalline forms of imatinib base, imatinib base free of desmethyl imatinib, and imatinib mesylate free of desmethyl imatinib mesylate, processes of their preparation and pharmaceutical compositions of imatinib mesylate.
    Type: Application
    Filed: October 26, 2007
    Publication date: August 28, 2008
    Inventors: Peter MacDonald, Pierluigi Rossetto, Alexandr Jegorov, Andrea Giolito, Dario Tentorio, Augusto Canavesi
  • Processes for preparing palonosetron salts
    Publication number: 20080200681
    Abstract: The present invention provides processes for preparing Palonosetron salts, especially, the hydrochloride salt and intermediates used to prepare Palonosetron salts.
    Type: Application
    Filed: October 23, 2007
    Publication date: August 21, 2008
    Inventors: Pierluigi Rossetto, Peter MacDonald, Ettore Bigatti, Gaia Banfi, Dario Tentorio
  • Process for the preparation of imatinib
    Publication number: 20080103305
    Abstract: The present invention provides process for the preparation of Imatinib and Imatinib salts, including processes that prepare intermediates for the production of Imatinib.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 1, 2008
    Inventors: Peter MacDonald, Pierluigi Rossetto
  • Crystalline forms of ciclesonide
    Publication number: 20070232578
    Abstract: The invention encompasses a crystalline form of ciclesonide characterized by an XRD pattern having peaks at about 11.0, 14.8, 15.7, 16.5, and 22.8 degrees two-theta±0.2 degrees two-theta, methods of its preparation and pharmaceutical compositions thereof.
    Type: Application
    Filed: February 7, 2007
    Publication date: October 4, 2007
    Inventors: Pierluigi Rossetto, Peter MacDonald, Sigalit Levi, Judith Aronhime
  • Process for the preparation of ciclesonide
    Publication number: 20070135398
    Abstract: Provided is a process for increasing the 22R/22S epidemic ratio of ciclesonide.
    Type: Application
    Filed: November 2, 2006
    Publication date: June 14, 2007
    Inventors: Pierluigi Rossetto, Peter MacDonald
  • Crystalline forms fenoldopam mesylate
    Publication number: 20070066594
    Abstract: The invention provides new crystalline forms of fenoldopam mesylate, i.e. fenoldopam mesylate Type I, fenoldopam mesylate Type III, fenoldopam mesylate Type V, and fenoldopam mesylate Type VI, methods of preparing the crystalline forms, and pharmaceutical compositions comprising the fenoldopam mesylate crystalline forms of the invention.
    Type: Application
    Filed: August 15, 2006
    Publication date: March 22, 2007
    Inventors: Peter MacDonald, Ettore Bigatti, Pierluigi Rossetto, Judith Aronhime, Sigalit Levi
  • Process for the preparation of letrozole
    Publication number: 20070066831
    Abstract: The invention provides a high-yield process for the preparation of letrozole having a high purity, without the need for removal of the 4-[1-(1,3,4-triazolyl)methyl]benzonitrile impurity at the intermediate stage. The invention also provides a process for the synthesis of letrozole in which formation of the impurity 4-[1-(1,3,4-triazolyl)methyl]benzonitrile during the first stage is minimized. In the process, a 4-(halomethyl)benzonitrile is reacted with a salt of 1H-1,2,4-triazole, reducing the formation of the impurity. Preferably, the preparation is conducted as a one-pot process.
    Type: Application
    Filed: July 6, 2006
    Publication date: March 22, 2007
    Inventors: Peter MacDonald, Ettore Bigatti, Pierluigi Rossetto, Zvi Harel