Patents by Inventor Pierre A. Jacobs

Pierre A. Jacobs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11931343
    Abstract: Compounds, such as compounds having Formula (I): wherein each variable is as described herein, that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: March 19, 2024
    Assignee: Arcus Biosciences, Inc.
    Inventors: Joel Beatty, Laurent Pierre Paul Debien, Samuel Lawrie Drew, Jeremy Fournier, Rebecca Louise Grange, Steven Donald Jacob, Jenna Leigh Jeffrey, Kenneth V. Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Debashis Mandal, Jay Patrick Powers, Anh Thu Tran, Rhiannon Thomas-Tran, Xuelei Yan
  • Publication number: 20200339881
    Abstract: A method for inerting polluted soil, comprising adding to a polluted soil a composition comprising: from 40% to 99% of a sulfoaluminous clinker comprising as a phase composition, to the overall weight of the clinker: from 5% to 80% of a calcium sulfoaluminate phase possibly iron-doped corresponding to the formula C4AxFy$z in which x varies from 2 to 3; y varies from 0 to 0.5; and z varies from 0.8 to 1.2; from 0 to 25% of a calcium aluminoferrite phase of a composition corresponding to the general formula C6Ax?Fy?; x? varies from 0 to 1.5; and y? varies from 0.5 to 3; and from 10% to 70% of a belite phase C2S; and from 1% to 60% of a lime.
    Type: Application
    Filed: February 19, 2019
    Publication date: October 29, 2020
    Applicant: VICAT
    Inventors: Yvan-Pierre JACOB, Laury BARNES-DAVIN, Virginie NOWALSKI
  • Patent number: 9422192
    Abstract: The invention relates to a vertical-shaft kiln (2) for manufacturing a clinker, including: a tubular enclosure (4) comprising from top to bottom: a feeder section (14); a decarbonatation section (16) exhibiting a slanted lower surface (16a); a clinkering section (18) exhibiting a slanted lower surface (18a); a first collection section (20) extending substantially vertically; first extraction means (42) arranged for extracting the clinker from the first collection section (20); means arranged for generating a first gas exhibiting a temperature ranging between 950° C. and 1250° C., and for supplying the first gas in the decarbonatation section (16); means arranged for generating a second oxidizing gas exhibiting a temperature ranging between 1250° C. and 1450° C., and for supplying the second oxidizing gas in the clinkering section (18); and first suction means for suctioning the first and second gas from the feeder section (14).
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: August 23, 2016
    Assignee: VICAT
    Inventors: Yvan-Pierre Jacob, Michel Pasquier, Dominique Renie, Guy Beauvent
  • Patent number: 9296294
    Abstract: Noise reduction baffle for a fuel tank comprising a lower carrier and an upper sliding part which can slide relatively to the carrier thanks to compression springs mounted on retainers, said lower carrier having a hollow foot comprising two vertical or inclined walls defining an open cavity of elongated shape having a longitudinal axis, said cavity comprising at least one rib making an angle with the longitudinal axis of the cavity.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: March 29, 2016
    Assignee: INERGY AUTOMOTIVE SYSTEMS RESEARCH (Societe Anonyme)
    Inventors: Pierre Jacob, Yohann L'Hermite, Herve Guillerme, Thibaut Prouveur, Laurent Guyotte
  • Publication number: 20150210593
    Abstract: The invention relates to a vertical-shaft kiln (2) for manufacturing a clinker, including: a tubular enclosure (4) comprising from top to bottom: a feeder section (14); a decarbonatation section (16) exhibiting a slanted lower surface (16a); a clinkering section (18) exhibiting a slanted lower surface (18a); a first collection section (20) extending substantially vertically; first extraction means (42) arranged for extracting the clinker from the first collection section (20); means arranged for generating a first gas exhibiting a temperature ranging between 950° C. and 1250° C., and for supplying the first gas in the decarbonatation section (16); means arranged for generating a second oxidizing gas exhibiting a temperature ranging between 1250° C. and 1450° C., and for supplying the second oxidizing gas in the clinkering section (18); and first suction means for suctioning the first and second gas from the feeder section (14).
    Type: Application
    Filed: July 12, 2013
    Publication date: July 30, 2015
    Inventors: Yvan-Pierre Jacob, Michel Pasquier, Dominique Renie, Guy Beauvent
  • Patent number: 8716543
    Abstract: A process to make propylene can include providing a reaction zone containing a catalyst and introducing a feedstock into the reaction zone. The catalyst can be an acid. The feedstock can include ethylene, dimethyl ether or methanol and dimethyl ether with at least 1000 wppm of dimethyl ether, and optionally steam. The feedstock can be contacted with the catalyst at temperature and pressure conditions to produce an effluent, including propylene, hydrocarbons, steam, optionally unconverted methanol and/or unconverted dimethyl ether and optionally unconverted ethylene. The temperature at the inlet of the reaction zone can be under 280° C., such as from 50 to 280° C. The effluent can be sent to a fractionation zone to recover propylene, optionally methanol, dimethyl ether and optionally ethylene. At least a part of methanol, dimethyl ether, and ethylene can be recycled to the reaction zone at step b).
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: May 6, 2014
    Assignee: Total Research & Technology Feluy
    Inventors: Pieter Struelens, Pierre Jacobs, Nikolai Nesterenko, Delphine Minoux, Sander Van Donk, Jean-Pierre Dath
  • Publication number: 20130274319
    Abstract: The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device. In order to increase the bio-compatibility of this device, it is provided with at least one coating. The coating contains a therapeutic agent which is comprised in a matrix that sticks to the intraluminal device. Instead of being formed by a little bio-compatible polymer, the matrix is formed by a bio-compatible oil or fat, such as cod-liver oil or olive oil. Preferably, the bio-compatible oil or fat further comprises alfa-tocopherol.
    Type: Application
    Filed: June 7, 2013
    Publication date: October 17, 2013
    Inventors: Maria Dhondt, Ivan De Scheerder, Pierre Jacobs, Johan Martens
  • Patent number: 8557039
    Abstract: The invention relates to a method for manufacturing a sulfoaluminous or belitic sulfoaluminous clinker from a raw mix formed from a mixture including minerals containing calcium, aluminum, silica, iron, and sulfur, preferably in sulfate form, and is characterized in that the method comprises the steps including: at least partially dehydrating and decarbonating the mixture through placement in a vertical kiln (1) comprising a substantially vertical chamber (2) wherein the mixture is heated, the chamber (2) of the vertical kiln (1) being supplied with hot gases the temperature of which is between 900 and 1150° C.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: October 15, 2013
    Assignee: VICAT
    Inventors: Yvan-Pierre Jacob, Jacques Croce, Guy Beauvent, René De La Fouchardiere, Dominique Renie
  • Patent number: 8460693
    Abstract: The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device. In order to increase the bio-compatibility of this device, it is provided with at least one coating. The coating contains a therapeutic agent which is comprised in a matrix that sticks to the intraluminal device. Instead of being formed by a little bio-compatible polymer, the matrix is formed by a bio-compatible oil or fat, such as cod-liver oil or olive oil. Preferably, the bio-compatible oil or fat further comprises alfa-tocopherol.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: June 11, 2013
    Assignee: Atrium Medical Corporation
    Inventors: Maria Dhondt, Ivan De Scheerder, Pierre Jacobs, Johan Martens
  • Publication number: 20130137914
    Abstract: The present invention is a process to make propylene comprising: a) providing a reaction zone containing a catalyst; b) introducing a feedstock comprising ethylene, dimethyl ether or methanol and dimethyl ether comprising at least 1000 wppm of dimethyl ether, optionally steam into said reaction zone and into contact with said catalyst; c) operating said reaction zone at temperature and pressure conditions to produce an effluent comprising propylene, hydrocarbons, steam, optionally unconverted methanol and/or unconverted dimethyl ether and optionally unconverted ethylene; d) sending the effluent of step c) to a fractionation zone to recover propylene optionally methanol and for dimethyl ether and optionally ethylene; e) optionally recycling at least a part of methanol and for dimethyl ether and optionally recycling at least a part of ethylene to the reaction zone at step b); wherein the catalyst is an acid and the temperature at the inlet of the reaction zone is under 280° C.
    Type: Application
    Filed: March 15, 2011
    Publication date: May 30, 2013
    Applicant: TOTAL RESEARCH & TECHNOLOGY FELUY
    Inventors: Pieter Struelens, Pierre Jacobs, Nikolai Nesterenko, Delphine Minoux, Sander Van Donk, Jean-Pierre Dath
  • Patent number: 8217206
    Abstract: The present invention is a process for converting methane to methanol, comprising: feeding methane and gaseous air or oxygen or gaseous air enriched with oxygen to a reactor under an elevated pressure; said reactor having an internal surface, made of silica or coated with silica, surrounding a zone in which said gases react; and reacting said gases in said reaction zone at an elevated temperature at conditions effective to produce methanol and for valuable oxygenates. Advantageously the internal surface is made of quartz or coated with quartz Advantageously the internal surface, made of silica (advantageously quartz) or coated with silica (advantageously quartz), is treated with HF before the conversion of methane to methanol. Advantageously the reaction is carried out in the absence in said reaction zone of any added material which measurably affects the rate of the reaction or the yield of the product. Advantageously the reactor is operated under a pressure from 1 to 7.5 MPa.
    Type: Grant
    Filed: July 4, 2008
    Date of Patent: July 10, 2012
    Assignee: Total Petrochemicals Research Feluy
    Inventors: Hendrik De Winne, Pierre Jacobs, Bert Sels, Walter Vermeiren
  • Patent number: 8080692
    Abstract: The invention relates generally to the production of oxygenated hydrocarbons such as lower alcohols and more preferably 1,2-propanediol. More particularly, this invention comprises a single-step catalytic process for the catalytic production of lower alcohols such as methanol, ethanol, ethylene glycol and 1,2-propanediol from glycerol in aqueous medium. The catalyst comprises a metal selected from the Group VIII transition metals, preferably platinum, alloys thereof and mixtures thereof and a microporous carrier, preferably a faujasite-type zeolite.
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: December 20, 2011
    Assignee: Katholieke Universiteit Leuven
    Inventors: Els D'Hondt, Pierre Jacobs, Bert Sels
  • Publication number: 20110201861
    Abstract: The present invention relates to a process for making a crystalline metallosilicate composition and comprising crystallites having an inner part (the core) and an outer part (the outer layer or shell) such that: the ratio Si/Metal is higher in the outer part than in the inner part, the crystallites have a continuous distribution of metal and silicon over the crystalline cross-section, said process comprising: a) providing an aqueous medium comprising OH? anions and a metal source, b) providing an aqueous medium comprising an inorganic source of silicon and optionally a templating agent, c) optionally providing a non aqueous liquid medium comprising optionally an organic source of silica, d) mixing the medium a), b) and the optional c) at conditions effective to partly crystallize the desired metallosilicate, e) cooling down the reaction mixture a)+b)+c) to about room temperature, f) decreasing the pH of the reaction mixture by at least 0.1 preferably by 0.3 to 4, more preferably by 0.
    Type: Application
    Filed: February 24, 2009
    Publication date: August 18, 2011
    Applicant: TOTAL PETROCHEMICALS RESEARCH FELUY
    Inventors: Metin Bulut, Pierre Jacobs, Delphine Minoux, Nikolai Nesterenko, Jean-Pierre Dath, Sander Van Donk
  • Publication number: 20110190561
    Abstract: The present invention relates to a process for making a crystalline metallosilicate composition comprising crystallites having an inner part (the core) and an outer part (the outer layer or shell) such that: the ratio Si/metal is higher in the outer part than in the inner part, the crystallites have a continuous distribution of metal and silicon over the crystalline cross-section, said process comprising: a) providing an aqueous medium comprising OH— anions and a metal source, b) providing an aqueous medium comprising an inorganic source of silicon and optionally a templating agent, c) optionally providing a non aqueous liquid medium comprising optionally an organic source of silica, d) mixing the medium a), b) and the optional c) at conditions effective to crystallyze the desired metallosilicate, e) recovering the desired metallosilicate, wherein in the mixture a)+b)+c), before crystallization, the ratio Si org/Si inorganic is <0.3, advantageously <0.
    Type: Application
    Filed: February 24, 2009
    Publication date: August 4, 2011
    Applicant: TOTAL PETROCHEMICALS RESEARCH FELUY
    Inventors: Metin Bulut, Pierre Jacobs, Delphine Minoux, Nikolai Nesternko, Jean-Pierre Dath, Sander Van Donk
  • Publication number: 20110155743
    Abstract: Noise reduction baffle for a fuel tank comprising a lower carrier and an upper sliding part which can slide relatively to the carrier thanks to compression springs mounted on retainers, said lower carrier having a hollow foot comprising two vertical or inclined walls defining an open cavity of elongated shape having a longitudinal axis, said cavity comprising at least one rib making an angle with the longitudinal axis of the cavity.
    Type: Application
    Filed: September 9, 2009
    Publication date: June 30, 2011
    Applicant: INERGY AUTOMOTIVE SYSTEMS RESEARCH (Societe Anonyme)
    Inventors: Pierre Jacob, Yohann L'Hermite, Herve Guillerme, Thibaut Prouveur, Laurent Guyotte
  • Patent number: 7960585
    Abstract: The present invention relates to a process for preparing secondary amides with good selectivity by carbonylating a corresponding tertiary amine with carbon monoxide in a reaction mixture in the presence of a metal catalyst and in the presence of a halogen containing promoter. The metal catalyst comprises palladium. A same or even a much better catalytic activity can be obtained with palladium than with the much more expensive rhodium, especially when the palladium is used in a low concentration. Moreover, also a good selectivity can be achieved.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: June 14, 2011
    Assignee: Taminco
    Inventors: Mondher Srasra, Pierre Jacobs, Bert Sels, Maria Christina Jacoba Tielen, Kristof Moonen, Peter Roose, Ivan Vanden Eynde
  • Publication number: 20110124934
    Abstract: The present invention provides a method for preparing a metallosilicate of MFI type, wherein organic templates, seeding techniques, using low aliphatic alcohols miscible with water or homogeneous starting solutions are not required. The present invention relates to a process for making a crystalline metallosilicate with high Si/Metal ratio comprising: a) providing an aqueous medium comprising OH? anions and a metal source, b) providing an aqueous medium comprising an inorganic water insoluble source of silicon, c) optionally providing a non aqueous liquid medium comprising optionally an organic source of silica, d) mixing the medium a), b) and the optional c) at conditions effective to crystallize the desired metallosilicate, e) recovering the desired metallosilicate, wherein in the mixture a)+b)+c), before crystallization, the ratio Si org/Si inorganic is <0.3, advantageously <0.2 and preferably 0, the molar ratio OH?/SiO2 is at least 0.3, advantageously from 0.3 to 0.62, preferably from 0.
    Type: Application
    Filed: February 24, 2009
    Publication date: May 26, 2011
    Applicant: TOTAL PETROCHEMICALS RESEARCH FELUY
    Inventors: Metin Bulut, Pierre Jacobs, Delphine Minoux, Nikolai Nesterenko, Jean-Pierre Dath, Sander Van Donk
  • Publication number: 20110098488
    Abstract: Oxidation of organic substrates by means of singlet oxygen, in which organic substrates which react with 1O2 are admixed with 10-70% H2O2 in an organic solvent in the presence of a molybdate LDH catalyst modified by ethylene glycol, polyethylene glycol or polyol, and the catalytic decomposition of H2O2 to water and 1O2 is then followed by the oxidation to the corresponding oxidation products, and also modified molybdate LDH catalysts.
    Type: Application
    Filed: March 18, 2006
    Publication date: April 28, 2011
    Inventors: Dirk De Vos, Pierre Jacobs, Joos Wahlen, Paul Alsters, Walther Jary
  • Publication number: 20110073013
    Abstract: The invention relates to a method for manufacturing a sulfoaluminous or belitic sulfoaluminous clinker from a raw mix formed from a mixture including minerals containing calcium, aluminum, silica, iron, and sulfur, preferably in sulfate form, and is characterized in that the method comprises the steps including: at least partially dehydrating and decarbonating the mixture through placement in a vertical kiln (1) comprising a substantially vertical chamber (2) wherein the mixture is heated, the chamber (2) of the vertical kiln (1) being supplied with hot gases the temperature of which is between 900 and 1150° C; extracting the dehydrated and decarbonated mixture from the vertical kiln (1) and conveying the same in a continuous kiln (4) comprising a furnace (5) and a transporting means (6) for transporting the mixture across the furnace (5); heating the mixture from the vertical kiln (1) by passing the mixture through the furnace (5) via the transporting means (6) such that a clinkerization of the mixture is ob
    Type: Application
    Filed: March 12, 2009
    Publication date: March 31, 2011
    Applicant: VICAT
    Inventors: Yvan-Pierre Jacob, Jacques Croce, Guy Beauvent, Rene De La fouchardiere, Dominique Renie
  • Publication number: 20100280289
    Abstract: The present invention is a process for converting methane to methanol, comprising: feeding methane and gaseous air or oxygen or gaseous air enriched with oxygen to a reactor under an elevated pressure; said reactor having an internal surface, made of silica or coated with silica, surrounding a zone in which said gases react; and reacting said gases in said reaction zone at an elevated temperature at conditions effective to produce methanol and for valuable oxygenates. Advantageously the internal surface is made of quartz or coated with quartz Advantageously the internal surface, made of silica (advantageously quartz) or coated with silica (advantageously quartz), is treated with HF before the conversion of methane to methanol. Advantageously the reaction is carried out in the absence in said reaction zone of any added material which measurably affects the rate of the reaction or the yield of the product. Advantageously the reactor is operated under a pressure from 1 to 7.5 MPa.
    Type: Application
    Filed: July 4, 2008
    Publication date: November 4, 2010
    Applicant: TOTAL PETROCHEMICALS RESEARCH FELUY
    Inventors: Hendrik De Winne, Pierre Jacobs, Bert Sels, Walter Vermeiren