Patents by Inventor Pierre Acklin

Pierre Acklin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
    Patent number: 6723742
    Abstract: The use is described of 3,5-diphenyl-1,2,4-triazoles of the formula I in which R1-R5 are as defined in the description. The compounds have useful pharmaceutical properties and are particularly active as iron chelators. They can be used for the treatment of iron overload in warm-blooded animals.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: April 20, 2004
    Assignee: Novartis AG.
    Inventors: René Lattmann, Pierre Acklin
  • Substituted 3, 5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
    Publication number: 20030203954
    Abstract: The use is described of 3,5-diphenyl-1,2,4-triazoles of the formula I 1
    Type: Application
    Filed: May 29, 2003
    Publication date: October 30, 2003
    Inventors: Rene Lattmann, Pierre Acklin
  • Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
    Patent number: 6596750
    Abstract: The use is described of 3,5-diphenyl-1,2,4-triazoles of the formula I in which R1-R5 are as defined in the description. The compounds have useful pharmaceutical properties and are particularly active as iron chelators. They can be used for the treatment of iron overload in warm-blooded animals.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: July 22, 2003
    Assignee: Novartis AG
    Inventors: René Lattmann, Pierre Acklin
  • Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
    Publication number: 20030069273
    Abstract: The use is described of 3,5-diphenyl-1,2,4-triazoles of the formula I 1
    Type: Application
    Filed: September 23, 2002
    Publication date: April 10, 2003
    Inventors: Rene Lattmann, Pierre Acklin
  • Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
    Patent number: 6465504
    Abstract: The use is described of 3,5-diphenyl-1,2,4-triazoles of the formula I in which R1-R5 are as defined in the description. The compounds have useful pharmaceutical properties and are particularly active as iron chelators. They can be used for the treatment of iron overload in warm-blooded animals.
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: October 15, 2002
    Assignee: Novartis AG
    Inventors: René Lattmann, Pierre Acklin
  • Substituted aminoalkane phosphonic acids
    Patent number: 6117873
    Abstract: Compounds of the formula I ##STR1## in which R.sub.1 is hydroxyl or an aliphatic, araliphatic or aromatic radical,X is a divalent aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic, heteroarylaliphatic or aromatic radical,R.sub.2 is hydrogen or an aliphatic or araliphatic radical, alk is lower alkylidene andR.sub.3, R.sub.4 and R.sub.5 independently of one another are hydrogen, lower alkyl, halogen, trifluoromethyl, cyano or nitro,and their salts can be used for the treatment of pathological conditions which respond to blockage of excitatory amino acid receptors, and for the production of pharmaceutical preparations.
    Type: Grant
    Filed: April 23, 1999
    Date of Patent: September 12, 2000
    Assignee: Novartis AG
    Inventors: Pierre Acklin, Hans Allgeier, Yves Auberson, Silvio Ofner, Siem Jacob Veenstra
  • 2,3-dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives
    Patent number: 6080743
    Abstract: 2,3-Dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives of formula (I), ##STR1## wherein one of the radicals R.sub.1, and R.sub.2 is a group R.sub.5 and the other is a group of formula --CH(R.sub.6)--alk--R.sub.7 (Ia), --alk--CH(R.sub.6 -R.sub.7 (Ib), --alk--N(R.sub.8)--X--R.sub.7 (Ic), --alk--N.sup.+ (R.sub.8)(R.sup.9)--X--R.sub.7 A.sup.- (Id), --alk--O--X--R.sub.7 (Ie) or --alk--S--X--R.sub.7 (If), R.sub.3, R.sub.4 and R.sub.5 are each independently of the others hydrogen, lower alkyl, halogen, trifluoromethyl, cyano or nitro, R.sub.6 is unsubstituted or lower alkylated and/or lower alkanoylated amino, R.sub.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: June 27, 2000
    Assignee: Novartis AG
    Inventors: Pierre Acklin, Hans Allgeier, Yves Auberson, Michel Biollaz, Robert Moretti, Silvio Ofner, Siem Jacob Veenstra