Patents by Inventor Pierre-Alain Rubbo

Pierre-Alain Rubbo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGENIC PEPTIDES AND USE THEREOF
    Publication number: 20210199657
    Abstract: The invention relates to an in vitro method of screening immunogenic peptides of interest, capable of recognizing antibodies originating from the serum of individuals suffering from active tuberculosis, said method comprising:—bringing into contact of peptides of the serum originating from patients suffering from active tuberculosis—detecting the formation of immune complexes in the preceding step, and—selecting peptides of interest for which the value of a ratio R is greater than or equal to 1.5, the ratio R being the measurement value of the formation of immune complexes to the measurement value obtained from the control sample.
    Type: Application
    Filed: February 24, 2017
    Publication date: July 1, 2021
    Inventors: Pierre-Alain Rubbo, Edouard Tuaillon
  • Diagnosis method of active tuberculosis
    Patent number: 9274110
    Abstract: The present invention relates to a method for the in vitro diagnosis of active tuberculosis, comprising a step of contacting lymphocytes of a patient suspected to have active tuberculosis with at least one protein of mycobacteria, said protein being an enzyme having a lipolytic activity, and a step of detecting the presence of specific activated lymphocytes.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: March 1, 2016
    Assignees: Universite Montpellier 2 Sciences et Technique, Universite Montpellier 1, Centre Hospitalier Universitaire de Montpellier, Centre National de La Recherche Scientifique
    Inventors: Edouard Tuaillon, Pierre-Alain Rubbo, Stephane Canaan, Laurent Kremer, Nicolas Nagot, Philippe Van De Perre, Jean-Pierre Vendrell
  • METHODS AND KITS FOR DIAGNOSING LATENT TUBERCULOSIS INFECTION
    Publication number: 20140342936
    Abstract: The present invention relates to a method for diagnosing latent tuberculosis infection in a subject comprising the step i) consisting of incubating a biological sample obtained from the subject with at least one Mycobacterium tuberculosis antigen, and thereafter a step ii) consisting of quantifying in said biological sample the secretion of at least one cytokine selected from the group consisting of IL-2, IL-15, IP-10 and MIG.
    Type: Application
    Filed: December 17, 2012
    Publication date: November 20, 2014
    Inventors: Pierre-Alain Rubbo, Nicolas Nagot, Edouard Tuaillon, Philippe Van De Perre
  • DIAGNOSIS METHOD OF ACTIVE TUBERCULOSIS
    Publication number: 20140220599
    Abstract: The present invention relates to a method for the in vitro diagnosis of active tuberculosis, comprising a step of contacting lymphocytes of a patient suspected to have active tuberculosis with at least one protein of mycobacteria, said protein being an enzyme having a lipolytic activity, and a step of detecting the presence of specific activated lymphocytes.
    Type: Application
    Filed: June 1, 2012
    Publication date: August 7, 2014
    Applicants: UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPTALER UNIVERSITAIRE DE MONTPELLIER, UNIVERSITE MONTPELLIER 1
    Inventors: Edouard Tuaillon, Pierre-Alain Rubbo, Stephane Canaan, Laurent Kremer, Nicolas Nagot, Philippe Van De Perre, Jean-Pierre Vendrell