Patents by Inventor Pierre-Andre Chavaillaz

Pierre-Andre Chavaillaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MHC complexes and uses thereof
    Patent number: 7074904
    Abstract: The present invention relates to novel complexes of major histocompability complex (MHC) molecules and uses of such complexes. In particular, the invention relates to MHC fusion complexes that contain a MHC molecule with a peptide-binding groove and a presenting peptide covalently linked to the MHC protein. Fusion complexes of the invention are useful for a variety of applications including in vitro screens for identification and isolation of peptides that modulate activity of selected T cells, including peptides that are T cell receptor antagonists and partial agonists, methods of suppressing an immune response of a mammal and methods for inducing an immune response in a mammal.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: July 11, 2006
    Assignee: Altor Bioscience Corporation
    Inventors: Hing C. Wong, Peter R. Rhode, Jon A. Weidanz, Susan Grammer, Ana C. Edwards, Pierre-Andre Chavaillaz, Jin-An Jiao
  • MHC complexes and uses thereof
    Publication number: 20020198144
    Abstract: The present invention relates to novel complexes of major histocompability complex (MHC) molecules and uses of such complexes. In particular, the invention relates to MHC fusion complexes that contain a MHC molecule with a peptide-binding groove and a presenting peptide covalently linked to the MHC protein. Fusion complexes of the invention are useful for a variety of applications including in vitro screens for identification and isolation of peptides that modulate activity of selected T cells, including peptides that are T cell receptor antagonists and partial agonists, methods of suppressing an immune response of a mammal and methods for inducing an immune response in a mammal.
    Type: Application
    Filed: July 6, 2001
    Publication date: December 26, 2002
    Applicant: Dade International, Inc.
    Inventors: Hing C. Wong, Peter R. Rhode, Jon A. Weidanz, Susan Grammer, Ana C. Edwards, Pierre-Andre Chavaillaz, Jin-An J.J. Jiao
  • Peptide synthesis and purification by fusion to penI protein or precipitation effective portion thereof
    Patent number: 5888775
    Abstract: The present invention provides novel methods for the synthesis and isolation and purification of a peptide of interest (target peptide). In particular, the invention relates to peptide synthesis, isolation and purification methods that comprise use of penI fusion polypeptides and related gene fusion constructs that encode such polypeptides.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: March 30, 1999
    Assignee: Dade International Inc
    Inventors: Rony Tal, Hing C. Wong, Clayton Casipit, Pierre-Andre Chavaillaz, Vaughan Wittman
  • Methods for peptide synthesis and purification
    Patent number: 5763284
    Abstract: The present invention provides novel methods for the synthesis and isolation and purification of a peptide of interest (target peptide). In particular, the invention relates to peptide synthesis, isolation and purification methods that comprise use of penI fusion polypeptides and related gene fusion constructs that encode such polypeptides.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: June 9, 1998
    Assignee: Dade International Inc.
    Inventors: Rony Tal, Hing C. Wong, Clayton Casipit, Pierre-Andre Chavaillaz, Vaughan Wittman