Patents by Inventor Pierre-Andre Pittet

Pierre-Andre Pittet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs)
    Patent number: 7592477
    Abstract: The present invention is related to substituted methylene amide derivatives of formula (I) and use thereof for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or pyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, obesity, polycystic ovary syndrome (PCOS). In particular, the present invention is related to the use of substituted methylene amide derivatives of formula (I) to modulate, notably to inhibit the activity of PTPs. Also the present invention relates to a method of treating diabetes type II, obesity and to regulate the appetite of mammals. The present invention is furthermore related to novel substituted methylene amide derivatives and method of preparation thereof. Formula (I).
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: September 22, 2009
    Assignee: Laboratoires Serono SA
    Inventors: Dominique Swinnen, Agnes Bombrun, Jerome Gonzalez, Patrick Gerber, Pierre-Andre Pittet
  • Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases(ptps)
    Publication number: 20050124656
    Abstract: The present invention is related to substituted methylene amide derivatives of formula (I) and use thereof for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or pyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, obesity, polycystic ovary syndrome (PCOS). In particular, the present invention is related to the use of substituted methylene amide derivatives of formula (I) to modulate, notably to inhibit the activity of PTPs. Also the present invention relates to a method of treating diabetes type II, obesity and to regulate the appetite of mammals. The present invention is furthermore related to novel substituted methylene amide derivatives and method of preparation thereof. Formula (I).
    Type: Application
    Filed: January 27, 2003
    Publication date: June 9, 2005
    Applicant: APPLIED RESEARCH SYSTEMS ARS
    Inventors: Dominique Swinnen, Agnes Bombrun, Jerome Gonzalez, Patrick Gerber, Pierre-Andre Pittet