Abstract: The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers.

Abstract: The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers.

Abstract: The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers.

Abstract: A method of optimizing a layout of selected parts to be cut from a piece of raw material such as wood, uses data representing geometric and defect-related characteristics of the each piece and data representing geometric and grade characteristics of a set of parts to be cut. A subset of parts characterized by a predetermined grade (quality) value and associated with a predetermined group of dimension values (width/length) is defined, as well as an arrangement of subdivided piece surface sections to be obtained through a primary cutting operation according to one or more of the width/length values. One or more subsections included in each piece surface section is defined according to the geometric and defect-related characteristics of the piece, and, for each subsection, a plurality of arrangements of parts to be included therein and selected from the subset of parts, to be obtained through a secondary cut operation, are defined.