Patents by Inventor Pierre Courbat

Pierre Courbat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4644011
    Abstract: Pharmaceutical preparations containing (+)-cyanidan-3-ol derivatives of the formula I ##STR1## wherein R' and R" are hydrogen, an unsubstituted or substituted hydrocarbon radical, or heterocyclic radical, halogen, formyl, free or functionally modified carboxyl, free or etherified or esterified hydroxyl, free, etherified or oxidized mercapto, unsubstituted or substituted sulfamoyl, acyl or unsubstituted or substituted amino, where however R' and R" cannot both be hydrogen simultaneously, and R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are each hydrogen or an unsubstituted or substituted hydrocarbon radical, and R.sub.2 and R.sub.3 together can also be an unsubstituted or substituted methylene group, and R.sub.1 also an acyl group or an amidated carboxyl group; and therapeutically applicable salts of these compounds, as well as new compounds of these preparations.These pharmaceutical preparations are particularly valuable for treating liver and venous diseases.
    Type: Grant
    Filed: July 9, 1985
    Date of Patent: February 17, 1987
    Assignee: Zyma SA
    Inventors: Marc E. Ballenegger, Christian G. Rimbault, Alban I. Albert, Andre J. Weith, Pierre Courbat, Robert G. Tyson, Derek R. Palmer, David G. Thompson
  • Patent number: 4634718
    Abstract: The present invention relates to the use of O-substituted derivatives of (+)-cyanidan-3-ol corresponding to the formula ##STR1## and their addition salts, in which R represents an optionally substituted hydrocarbon radical, an acyl radical of an organic carboxylic acid containing at least 2 carbon atoms, of a carbonic acid, or of an organic sulphonic acid, of a radical of an inorganic acid containing at least one oxygen atom, as compounds having immunomodulating properties, and pharmaceutical compositions for this purpose.
    Type: Grant
    Filed: February 28, 1986
    Date of Patent: January 6, 1987
    Assignee: Zyma SA
    Inventors: Pierre Courbat, Andre Weith, Alban Albert
  • Patent number: 4617296
    Abstract: The subject of the present invention is new O-substituted derivatives of (+)-cyanidan-3-ol corresponding to the general formula I ##STR1## in which R represents an optionally substituted hydrocarbon radical; an acyl radical of an organic carboxylic acid containing at least 2 carbon atoms, of a carbonic acid or of an organic sulphonic acid; or a radical of an inorganic acid containing at least one oxygen atom, with the exception of a glucosidic radical,and the salts thereof, a process for the preparation thereof as well as their application in therapeutics and medicaments containing these new products.These compounds have a valuable activity in the prevention of hepatic necrosis and also inhibit lipoperoxidation. In addition, they are capable of acting on the fibrillation of collagen.
    Type: Grant
    Filed: July 2, 1984
    Date of Patent: October 14, 1986
    Assignee: Ciba-Geigy Corporation
    Inventors: Alban Albert, Pierre Courbat, Andre Weith
  • Patent number: 4255336
    Abstract: The subject of the present invention is new O-substituted derivatives of (+)-cyanidan-3-ol corresponding to the general formula I ##STR1## in which R represents an optionally substituted hydrocarbon radical; an acyl radical of an organic carboxylic acid containing at least 2 carbon atoms, of a carbonic acid or of an organic sulphonic acid; or a radical of an inorganic acid containing at least one oxygen atom, with the exception of a glucosidic radical, and the salts thereof, a process for the preparation thereof as well as their application in therapeutics and medicaments containing these new products.These compounds have a valuable activity in the prevention of hepatic necrosis and also inhibit lipoperoxidation. In addition, they are capable of acting on the fibrillation of collagen.
    Type: Grant
    Filed: November 21, 1978
    Date of Patent: March 10, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Alban Albert, Pierre Courbat, Andre Weith
  • Patent number: 4153788
    Abstract: A process is provided for preparing mono-O-.beta.-hydroxyethyl-7-rutoside of the formula: ##STR1## which comprises contacting rutoside of the formula: ##STR2## in a solvent which is an at least partially aqueous medium with a boric acid alkali salt in an amount substantially not exceeding the amount necessary to form a boron complex of formula: reacting said boron complex with ethylene oxide to form a hydroxyethoxy compound of the formula ##STR3## and treating said hydroxyethoxy compound in an at least partially aqueous acid medium, whereby there is produced said mono-O-.beta.-hydroxyethyl-7-rutoside.
    Type: Grant
    Filed: March 7, 1977
    Date of Patent: May 8, 1979
    Assignee: ZYMA S.A.
    Inventors: Pierre Courbat, Alban Albert