Patents by Inventor Pierre De Clercq

Pierre De Clercq has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vitamin Danalogues for the prevention and treatment of bone disorders
    Patent number: 8258126
    Abstract: Novel vitamin D analogues are useful for making pharmaceutical compositions for the prevention or treatment of bone disorders such as osteoporosis.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: September 4, 2012
    Assignees: K.U. Leuven Research & Development, Universiteit Gent
    Inventors: Roger Bouillon, Annemieke Verstuyf, Pierre De Clercq, Maurits Vandewalle
  • 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]decanes
    Patent number: 7888338
    Abstract: The present invention relates to 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]-decanes, compositions which comprise said 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]-decanes, and methods for treating diseases, illnesses, and the like with said 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]decanes.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: February 15, 2011
    Assignees: K.U. Leuven Research & Development, Universiteit Gent
    Inventors: Roger Bouillon, Pierre De Clercq, Wim Schepens, Maurits Vandewalle, Annemieke Verstuyf
  • VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS
    Publication number: 20100160455
    Abstract: Novel vitamin D analogues are useful for making pharmaceutical compositions for the prevention or treatment of bone disorders such as osteoporosis
    Type: Application
    Filed: March 4, 2010
    Publication date: June 24, 2010
    Applicants: K.U. LEUVEN RESEARCH AND DEVELOPMENT, UNIVERSITEIT GENT
    Inventors: Roger Bouillon, Annemieke Verstuyf, Pierre De Clercq, Maurits Vandewalle
  • Vitamin Danalogues for the prevention and treatment of bone disorders
    Patent number: 7704986
    Abstract: Novel vitamin D analogues are useful for making pharmaceutical compositions for the prevention or treatment of bone disorders such as osteoporosis.
    Type: Grant
    Filed: October 17, 2005
    Date of Patent: April 27, 2010
    Assignees: K.U. Leuven Research and Development, Universiteit Gent
    Inventors: Roger Bouillon, Annemieke Verstuyf, Pierre De Clercq, Maurits Vandewalle
  • Substituted vitamin d analogues and their therapeutic uses
    Publication number: 20060189576
    Abstract: The present invention relates to analogues of vitamin D namely 14-epi-2-alkyl-19-nor vitamin D derivatives. Also a general method for the synthesis and the biological activities are described. The general formula is: (I) where R (? or ? oriented) represents an alkyl substituent and X part of a typical side chain of vitamin D or of one of its established analogues.
    Type: Application
    Filed: March 10, 2004
    Publication date: August 24, 2006
    Inventors: Roger Bouillon, Annemieke Verstuyf, Maurits Vandewalle, Pierre De Clercq
  • 7-(2-Cyclohexylidene-ethylidene)-spiro[4.5]decanes
    Publication number: 20060178350
    Abstract: The present invention relates to 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]-decanes, compositions which comprise said 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]-decanes, and methods for treating diseases, illnesses, and the like with said 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]decanes.
    Type: Application
    Filed: December 6, 2005
    Publication date: August 10, 2006
    Inventors: Roger Bouillon, Pierre De Clercq, Wim Schepens, Maurits Vandewalle, Annemieke Verstuyf
  • Vitamin D3 analog useful for the treatment of osteoporosis
    Publication number: 20060135491
    Abstract: The present invention relates to the vitamin D3 analog (1R,3R)-5-{(E)-(2R, 5R)-2-[2-(4-hydroxy-4-methylpentyl)-spiro[4.5]dec-7-ylidene]-ethylidene}-cyclohexane-1,3-diol which is useful in the treatment of osteoporosis.
    Type: Application
    Filed: December 6, 2005
    Publication date: June 22, 2006
    Inventors: Roger Bouillon, Pierre De Clercq, Wim Schepens, Maurits Vandewalle, Annemieke Verstuyf
  • Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof
    Patent number: 6191292
    Abstract: The invention relates to precursors of the A-ring of vitamin D, of the formula (I): in which A, R, R1 and R2 are as defined in the specification. The invention also relates to a method of preparing compounds (I) comprising the enzymatic asymmetrization of 3,5-dihydroxybenzoic acid derivatives, as well as intermediates of preparation of said compounds.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: February 20, 2001
    Assignee: Laboratoire Theramex
    Inventors: Jean-Claude Pascal, Maurits Vandewalle, Philippe Maillos, Pierre De Clercq
  • Photographic material containing a new hydrazide type
    Patent number: 5998087
    Abstract: A silver halide photographic material is disclosed containing a new type of hydrazide compounds represented by following general formula I, the different symbols of which are defined in the description. ##STR1## In a preferred embodiment Q is chosen from pyridinium, quinolinium or isoquinolinium. In a most preferred embodiment Q is a pyridinium substituted on the N.sup.+ with a C.sub.5 to C.sub.8 alkyl group.The photographic material is preferably a graphic arts recording material. High gradation and excellent hard dot quality are obtained.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: December 7, 1999
    Assignee: Agfa-Gevaert, N.V.
    Inventors: Johan Loccufier, Stefaan Lingier, Sabine Emmers, Jean-Marie Dewanckele, Pierre De Clercq, Noel Hosten, Dirk Van Haver
  • Photographic useful group releasing system
    Patent number: 5631125
    Abstract: A photographic element is disclosed containing a compound capable of releasing image-wise a photographic useful group (PUG) based on a mechanism involving radical formation under development conditions and splitting of a homolytically labile bond. In a preferred embodiment the compound capable of releasing the PUG is a hydrazine derivative or a 1-aryl-3-pyrazolidinone derivative.
    Type: Grant
    Filed: February 29, 1996
    Date of Patent: May 20, 1997
    Assignee: Agfa-Gevaert, N.V.
    Inventors: Jean-Marie Dewanckele, Johan Loccufier, Pierre De Clercq, Dirk Van Haver, Noel Hosten