Patents by Inventor Pierre Escoubas

Pierre Escoubas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of novel antagonist toxins of T-type calcium channel for analgesic purposes
    Patent number: 8664179
    Abstract: A peptide with the following sequence YCQKFLWTCDSERPCCEGLVCRLWCKIN (SEQ ID NO 1) or a derivative thereof, and nucleic acids coding for the peptide having the sequence (SEQ ID NO 1). Also the use of this peptide as an antagonist and/or reverse agonist of T-type calcium channels. A use of the peptide for preparing a drug, in particular an analgesic one.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: March 4, 2014
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite de Nice Sophia Antipolis
    Inventors: Emmanuel Bourinet, Pierre Escoubas, Fabrice Marger, Joel Nargeot, Michel Lazdunski
  • IDENTIFICATION OF NOVEL ANTAGONIST TOXINS OF T-TYPE CALCIUM CHANNEL FOR ANALGESIC PURPOSES
    Publication number: 20120040909
    Abstract: A peptide with the following sequence YCQKFLWTCDSERPCCEGLVCRLWCKIN (SEQ ID NO 1) or a derivative thereof, and nucleic acids coding for the peptide having the sequence (SEQ ID NO 1). Also the use of this peptide as an antagonist and/or reverse agonist of T-type calcium channels. A use of the peptide for preparing a drug, in particular an analgesic one.
    Type: Application
    Filed: January 15, 2010
    Publication date: February 16, 2012
    Applicants: UNIVERSITE DE NICE SOPHIA ANTIPOLIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
    Inventors: Emmanuel Bourinet, Pierre Escoubas, Fabrice Marger, Joel Nargeot, Michel Lazdunski
  • Polypeptide inhibiting a proton-gated Na+ channel, a nucleic acid coding for such polypeptide and a method of manufacturing an ASIC1a channel blocker
    Patent number: 7132505
    Abstract: The invention relates to a substantially pure polypeptide functioning as an ASIC1a channel blocker. Also provided is a nucleic acid molecule coding such polypeptide, pharmaceutical composition containing such polypeptide and a method of manufacturing an ASIC1a channel blocker.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: November 7, 2006
    Assignee: Centre National de la Recherche Scientifique - CNRS
    Inventors: Michel Lazdunski, Pierre Escoubas, Jan DeWeille, Sylvie Diochot
  • Insecticidal peptides and methods for use of same
    Publication number: 20020197689
    Abstract: This invention relates to the purification of a group of insecticidally effective toxin peptides isolated from the venoms of the Paracoelotes and Xysticus species of spiders. The toxin peptides are characterized by their neurotoxic effect on insect pest and potential for little, if any, toxicity in mammals. Coding polynucleotide sequences for the toxin peptides are described, as are methods and vectors for production and targeted delivery of recombinant toxin peptides. Methods for the use of the toxin peptides as insecticides are also provided.
    Type: Application
    Filed: March 22, 2001
    Publication date: December 26, 2002
    Inventors: Gerardo Corzo, Pierre Escoubas