Patents by Inventor Pierre-Francois Van de Moortele

Pierre-Francois Van de Moortele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230190105
    Abstract: Ultra-high field (“UHF”) magnetic resonance imaging (“MRI”) is used to localize the endopiriform nucleus (“EPN”) as a target for neuromodulation treatment. Single or multiple different image contrasts can be used to guide localization of the EPN. Treatment plan data are generated based on the localized EPN, and may include coordinate data, trajectory data, or both, for delivering neuromodulation treatment to the localized EPN.
    Type: Application
    Filed: October 5, 2020
    Publication date: June 22, 2023
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Thomas R. HENRY, Gregory F. MOLNAR, Michael C. PARK, Pierre-Francois VAN DE MOORTELE
  • Patent number: 10684337
    Abstract: A method for designing one or more multichannel, multiband radio frequency (“RF”) pulses for use with a magnetic resonance imaging (“MRI”) system is provided. The method includes determining a number of RF amplitude modulations and a number of RF phase modulations for each channel in a multichannel RF coil by minimizing an objective function that includes a complex-valued vector. The objective function also contains a system matrix that accounts for both a spatial sensitivity profile of each channel in the multichannel RF coil and a magnetic field map for each excitation band in the multiband RF pulse.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: June 16, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Xiaoping Wu, Pierre-Francois Van De Moortele, Sebastian Schmitter, Kamil Ugurbil, Edward Auerbach
  • Patent number: 10545210
    Abstract: Systems and methods for designing RF pulses using a technique that directly controls temperature rise via a compression model that is based on virtual observation points (“VOPs”) are provided. Thermal pre-simulations are first carried out for a given RF exposure time, coil, and subject model in order to obtain complex temperature matrices, after which the compression scheme follows. As one example, the thermal model employed can be Pennes' bio-heat equation. Focusing design constraints on the temperature rise instead of the absolute temperature allows for uncertain parameters to be dropped from the thermal model, making it more robust and less prone to errors. In some embodiments, the algorithm used for RF pulse design is the active-set (“A-S”) method.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: January 28, 2020
    Assignees: Regents of the University of Minnesota, Commissariat A L'Energie Atomique et Aux Energies Alternatives
    Inventors: Nicolas Boulant, Pierre-Francois Van De Moortele
  • Patent number: 10247803
    Abstract: Systems and methods for designing and/or using radio frequency (“RF”) pulses for in-vivo MRI applications, where the RF pulses are robust against errors due to physiological motion of organs during the respiratory cycle. For example, RF pulses are designed based on multi-channel B1+ maps correlated to different positions of the respiratory cycle.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: April 2, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Sebastian Schmitter, Pierre-Francois van de Moortele, Xiaoping Wu, Kamil Ugurbil
  • Patent number: 10191126
    Abstract: Systems and methods for producing an image of the electrical properties of an object using magnetic resonance imaging (“MRI”) are provided. The electrical properties are determined based on estimated gradient values of the electrical properties of the object. For instance, electrical property maps are reconstructed using a spatial integration on gradient values that are estimated from the magnitude and relative phase values derived from measurements of multiple transmit and receive B1fields. Specific absorption rate (“SAR”) maps can also be produced based on the estimated electrical properties.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: January 29, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Bin He, Jiaen Liu, Xiaotong Zhang, Pierre-Francois Van de Moortele
  • Publication number: 20170307710
    Abstract: Systems and methods for designing RF pulses using a technique that directly controls temperature rise via a compression model that is based on virtual observation points (“VOPs”) are provided. Thermal pre-simulations are first carried out for a given RF exposure time, coil, and subject model in order to obtain complex temperature matrices, after which the compression scheme follows. As one example, the thermal model employed can be Pennes' bio-heat equation. Focusing design constraints on the temperature rise instead of the absolute temperature allows for uncertain parameters to be dropped from the thermal model, making it more robust and less prone to errors. In some embodiments, the algorithm used for RF pulse design is the active-set (“A-S”) method.
    Type: Application
    Filed: September 22, 2015
    Publication date: October 26, 2017
    Inventors: Nicolas Boulant, Pierre-Francois Van De Moortele
  • Publication number: 20150362574
    Abstract: A method for designing one or more multichannel, multiband radio frequency (“RF”) pulses for use with a magnetic resonance imaging (“MRI”) system is provided. The method includes determining a number of RF amplitude modulations and a number of RF phase modulations for each channel in a multichannel RF coil by minimizing an objective function that includes a complex-valued vector. The objective function also contains a system matrix that accounts for both a spatial sensitivity profile of each channel in the multichannel RF coil and a magnetic field map for each excitation band in the multiband RF pulse.
    Type: Application
    Filed: January 24, 2014
    Publication date: December 17, 2015
    Inventors: Xiaoping Wu, Pierre-Francois Van De Moortele, Sebastian Schmitter, Kamil Ugurbil, Edward Auerbach
  • Publication number: 20140300354
    Abstract: Systems and methods for producing an image of the electrical properties of an object using magnetic resonance imaging (“MRI”) are provided. The electrical properties are determined based on estimated gradient values of the electrical properties of the object. For instance, electrical property maps are reconstructed using a spatial integration on gradient values that are estimated from the magnitude and relative phase values derived from measurements of multiple transmit and receive B1 fields. Specific absorption rate (“SAR”) maps can also be produced based on the estimated electrical properties.
    Type: Application
    Filed: April 4, 2014
    Publication date: October 9, 2014
    Inventors: Bin He, Jiaen Liu, Xiaotong Zhang, Pierre-Francois Van de Moortele
  • Patent number: 8193809
    Abstract: In one illustrative embodiment, a radio frequency (RF) coil is disclosed. The RF coil may include a plurality of transmission line elements, wherein at least one of the plurality of transmission line elements may have at least one dimension different than a dimension of another one of the plurality of transmission line elements. In some cases, each of the transmission line elements may include a signal line conductor and a ground plane conductor separated by a dielectric.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: June 5, 2012
    Assignee: Regents of the University of Minnesota
    Inventors: Can E. Akgun, Carl Snyder, Lance DelaBarre, Steen Moeller, Pierre-Francois Van de Moortele, John Thomas Vaughan, Kamil Ugurbil
  • Patent number: 7800368
    Abstract: A magnetic resonance system is disclosed. The system includes a transceiver having a multichannel receiver and a multichannel transmitter, where each channel of the transmitter is configured for independent selection of frequency, phase, time, space, and magnitude, and each channel of the receiver is configured for independent selection of space, time, frequency, phase and gain. The system also includes a magnetic resonance coil having a plurality of current elements, with each element coupled in one to one relation with a channel of the receiver and a channel of the transmitter. The system further includes a processor coupled to the transceiver, such that the processor is configured to execute instructions to control a current in each element and to perform a non-linear algorithm to shim the coil.
    Type: Grant
    Filed: February 17, 2007
    Date of Patent: September 21, 2010
    Assignee: Regents of the University of Minnesota
    Inventors: J. Thomas Vaughan, Pierre-Francois Van de Moortele, Lance DelaBarre, Christopher C. Olson, Heather Orser, Anand Gopinath, Kamil Ugurbil, Carl Snyder, Gregor Adiany, Can E. Akgun, Jinfeng Tian, John Strupp, Peter M. Andersen, Xiaoping Wu
  • Patent number: 7710117
    Abstract: A current unit having two or more current paths allows control of magnitude, phase, time, frequency and position of each of element in a radio frequency coil. For each current element, the current can be adjusted as to a phase angle, frequency and magnitude. Multiple current paths of a current unit can be used for targeting multiple spatial domains or strategic combinations of the fields generated/detected by combination of elements for targeting a single domain in magnitude, phase, time, space and frequency.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: May 4, 2010
    Assignee: Regents of the University of Minnesota
    Inventors: J. Thomas Vaughan, Gregor Adriany, Carl Snyder, Can E. Akgun, Jinfeng Tian, Kamil Ugurbil, Pierre-Francois Van de Moortele, Steen Moeller
  • Publication number: 20090115417
    Abstract: In one illustrative embodiment, a radio frequency (RF) coil is disclosed. The RF coil may include a plurality of transmission line elements, wherein at least one of the plurality of transmission line elements may have at least one dimension different than a dimension of another one of the plurality of transmission line elements. In some cases, each of the transmission line elements may include a signal line conductor and a ground plane conductor separated by a dielectric.
    Type: Application
    Filed: May 2, 2008
    Publication date: May 7, 2009
    Applicant: Regents of the University of Minnesota
    Inventors: Can E. Akgun, Carl Snyder, Lance DelaBarre, Steen Moeller, Pierre-Francois Van de Moortele, John Thomas Vaughan, Kamil Ugurbil
  • Patent number: 7514926
    Abstract: This document discusses, among other things, a system and method for a coil having a plurality of resonant elements and an adjustable frame. A position of at least one resonant element can be adjusted relative to at least one other resonant element. A variable impedance is coupled to adjacent resonant elements and the impedance varies as a function of a separation distance. Cables are coupled to each resonant element and are gathered at a junction in a particular manner.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: April 7, 2009
    Assignee: Regents of the University of Minnesota
    Inventors: Gregor Adriany, Pierre-Francois Van de Moortele, Johannes Ritter, William Voje, J. Thomas Vaughan, Kamil Ugurbil
  • Publication number: 20080084210
    Abstract: A current unit having two or more current paths allows control of magnitude, phase, time, frequency and position of each of element in a radio frequency coil. For each current element, the current can be adjusted as to a phase angle, frequency and magnitude. Multiple current paths of a current unit can be used for targeting multiple spatial domains or strategic combinations of the fields generated/detected by combination of elements for targeting a single domain in magnitude, phase, time, space and frequency.
    Type: Application
    Filed: September 20, 2007
    Publication date: April 10, 2008
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: J. Vaughan, Gregor Adriany, Carl Snyder, Can Akgun, Jinfeng Tian, Kamil Ugurbil, Pierre-Francois Van de Moortele, Steen Moeller
  • Publication number: 20070108980
    Abstract: This document discusses, among other things, a system and method for a coil having a plurality of resonant elements and an adjustable frame. A position of at least one resonant element can be adjusted relative to at least one other resonant element. A variable impedance is coupled to adjacent resonant elements and the impedance varies as a function of a separation distance. Cables are coupled to each resonant element and are gathered at a junction in a particular manner.
    Type: Application
    Filed: November 14, 2006
    Publication date: May 17, 2007
    Inventors: Gregor Adriany, Pierre-Francois Van de Moortele, Johannes Ritter, William Voje, J. Vaughan, Kamil Ugurbil
  • Patent number: RE47026
    Abstract: A magnetic resonance system is disclosed. The system includes a transceiver having a multichannel receiver and a multichannel transmitter, where each channel of the transmitter is configured for independent selection of frequency, phase, time, space, and magnitude, and each channel of the receiver is configured for independent selection of space, time, frequency, phase and gain. The system also includes a magnetic resonance coil having a plurality of current elements, with each element coupled in one to one relation with a channel of the receiver and a channel of the transmitter. The system further includes a processor coupled to the transceiver, such that the processor is configured to execute instructions to control a current in each element and to perform a non-linear algorithm to shim the coil.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: September 4, 2018
    Assignee: Regents of the University of Minnesota
    Inventors: J Thomas Vaughan, Pierre-Francois Van de Moortele, Lance DelaBarre, Chris E Olson, Heather Orser, Anand Gopinath, Kamil Ugurbil, Carl Snyder, Gregor Adriany, Can Akgun, Jinfeng Tian, John Strupp, Peter M Andersen