Patents by Inventor Pierre Graber

Pierre Graber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for Globular Adiponectin Production
    Publication number: 20090325229
    Abstract: This invention relates to methods for use in industrial production of recombinant globular Adiponectin (gAdiponectin). Specifically, the present invention provides a purification process suitable for production of high amounts of pure gAdiponectin. gAdiponectin is expressed in E. coli, and a purification method with which about 30 grams of gAdiponectin could be obtained from 100 liters of cell culture has been set up.
    Type: Application
    Filed: June 19, 2007
    Publication date: December 31, 2009
    Inventors: Pierre Graber, Andrew Topping, Philippe Baumgartner, Ewan Robert Robertson
  • Preparation of biologically active molecules
    Patent number: 7098002
    Abstract: Biologically active molecules are produced from their biologically inactive precursors by mutation of their native cleavage site to a site which is capable of being cleaved by a protease, and cleavage of the mutated molecule to yield a biologically active molecule.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: August 29, 2006
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Menachem Rubinstein, Bianling Liu, Daniela Novick, Pierre Graber