Patents by Inventor Pierre Henkart

Pierre Henkart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death
    Patent number: 5607831
    Abstract: Calpain has been identified as a component of the biochemical pathway in programmed cell death. Calpain inhibitors are effective in preventing the progression to cell death and can restore cell function. T lymphocytes from HIV infected individuals undergo T cell receptor-triggered programmed cell death which can be treated by calpain inhibitors and immune function can be restored in affected cells. Methods for diagnosing cell populations or individuals susceptible to programmed cell death and for monitoring therapeutic effectiveness are provided.
    Type: Grant
    Filed: March 25, 1993
    Date of Patent: March 4, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Pierre Henkart, Apurva Sarin, Mario Clerici, Gene M. Shearer