Patents by Inventor Pierre Henri Derible

Pierre Henri Derible has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4108994
    Abstract: A 5-thiazole-methane-amine selected from the group consisting of (1) compounds having the formula ##STR1## wherein R.sub.1 represents an alkyl having from 1 to 6 carbon atoms and R.sub.2 and R.sub.3 represent members selected from the group consisting of hydrogen, alkyl having from 1 to 6 carbon atoms, hydroxyalkyl having 1 to 6 carbon atoms, and, taken together, alkylene having up to 5 carbon atoms, azaalkylene having up to 4 carbon atoms, alkylalkylene having up to 5 carbon atoms in the alkylene and 1 to 4 carbon atoms in the alkyl, and alkylazaalkylene having up to 4 carbon atoms in the azaalkylene and 1 to 4 carbon atoms in the alkyl which may be in any position, and (2) its acid addition salts with non-toxic, pharmaceutically-acceptible acids; as well as processes for the preparation of the compounds and a process for use of the compounds as an antilipolytic agent.
    Type: Grant
    Filed: September 8, 1976
    Date of Patent: August 22, 1978
    Assignee: Roussel Uclaf
    Inventors: Andre Poittevin, Pierre Henri Derible, Robert Fournex
  • Patent number: 4018922
    Abstract: Novel 10-(piperidino-alkyl)-phenothiazines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, chlorine, --CF.sub.3, --OCH.sub.3 and SCH.sub.3, B and R are individually selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms, Z' is selected from the group consisting of hydrogen and alkyl of 1 to 10 carbon atoms, p is 0 or 1, n is 0, 1 or 2 and A is selected from the group consisting of hydrogen, --COOR.sub.2 and --COR.sub.1, R.sub.2 is linear alkyl of 1 to 15 carbon atoms and R.sub.1 is selected from the group consisting of alkyl of 1 to 18 carbon atoms optionally containing a double bond or --O-- and a polymethoxyphenyl and their non-toxic, pharmaceutically acceptable acid addition salts having neuroleptic, analgesic, spasmolytic and antihistaminic activity and their preparation and novel intermediates.
    Type: Grant
    Filed: March 25, 1975
    Date of Patent: April 19, 1977
    Assignee: Roussel-UCLAF
    Inventors: Pierre Henri Derible, Jean-Paul Lavaux
  • Patent number: 3988453
    Abstract: Novel phenothiazines of the formula ##SPC1##Wherein X is selected from the group consisting of hydrogen, chlorine, trifluoromethyl, methylthio and methoxy, B is selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms, p is 0 or 1, R is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms and R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having neuroleptic activity and frequently antihistaminic activity and their preparation.
    Type: Grant
    Filed: September 9, 1975
    Date of Patent: October 26, 1976
    Assignee: Roussel-UCLAF
    Inventors: Pierre Henri Derible, Jean-Paul Lavaux, Jacques Laurent
  • Patent number: 3975529
    Abstract: Novel 6,11-dihydrodibenzo(b,e)thiepines of the formula ##SPC1##Wherein A is selected from the group consisting of hydrogen and acyl of an alkanoic acid of 2 to 19 carbon atoms in the form of their optically active isomers or racemic mixtures thereof and their non-toxic, pharmaceutically acceptable acid addition salts having remarkable anticholinergic properties.
    Type: Grant
    Filed: June 24, 1975
    Date of Patent: August 17, 1976
    Assignee: Roussel-UCLAF
    Inventors: Pierre Henri Derible, Vesperto Torelli, Claude Dumont
  • Patent number: 3950527
    Abstract: N-[.omega.-(4'-(3"-indolyl)-piperidino)-alkyl]-benzamides of the formula ##SPC1##Wherein R is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms, n is 2 or 3, X is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms, X.sub.1 is selected from the group consisting of hydrogen, fluorine, chlorine, bromine, --NH.sub.2 and ##EQU1## and X.sub.2 is selected from the group consisting of hydrogen, chlorine and sulfamoyl and their non-toxic, pharmaceutically acceptable acid addition salts having neurosedative properties and their preparation.
    Type: Grant
    Filed: January 22, 1975
    Date of Patent: April 13, 1976
    Assignee: Roussel-UCLAF
    Inventors: Pierre Henri Derible, Jacques Guillaume, Claude Dumont
  • Patent number: 3947578
    Abstract: Novel [4'-(3"-indolyl)-piperidino]-alkyl-arylketones of the formula ##SPC1##Wherein R is selected from the group consisting of hydrogen and alkoxy of 1 to 5 carbon atoms, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, n is 2 or 3 and X is selected from the group consisting of hydrogen, fluorine, chlorine and bromine and their non-toxic, pharmaceutically acceptable acid addition salts having central nervous system depressant activity.
    Type: Grant
    Filed: September 18, 1974
    Date of Patent: March 30, 1976
    Assignee: Roussel Uclaf
    Inventors: Pierre Henri Derible, Jean-Paul Lavaux