Patents by Inventor Pierre Hilaire
Pierre Hilaire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9278015Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis so that the catheter system can be advanced as a unit. The catheter system is combined with drug eluting technology to prevent restenosis, inflammation and/or thrombosis and/or to promote reendothelialization in the vessel bifurcation. The main vessel stent and/or the sidebranch stent may be coated or impregnated with one or more drugs or bioactive substances. Alternatively or in addition, the first balloon and/or the second balloon may be coated with or include a mechanism for delivering one or more drugs or bioactive substances to the vessel wall.Type: GrantFiled: April 23, 2007Date of Patent: March 8, 2016Assignee: MinvasysInventors: Pierre Hilaire, Machiel Van Der Leest
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Patent number: 8814925Abstract: A catheter system including: a stent delivery catheter (2) having a proximal end and a distal end and an interior lumen extending between the proximal end and the distal end; a stent (1) having a proximal end and a distal end and a stent lumen extending between the proximal end and the distal end, the stent having an expanded state and an unexpanded state; and an embolic protection filter (3) having an expanded state and an unexpanded state; the catheter system having a deployed position and an undeployed position. When the catheter system is in the undeployed position, the stent (1) is in its unexpanded state and positioned within the interior lumen of the stent delivery catheter (2) and the embolic protection filter (3) is in its unexpanded state and positioned within the stent lumen of the stent.Type: GrantFiled: March 20, 2008Date of Patent: August 26, 2014Assignee: MinvasysInventors: Pierre Hilaire, Machiel Van De Leest
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Patent number: 8808359Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis. The linking device allows the catheter system to be advanced as a unit and helps prevent premature or inadvertent dislodgement of the stent from the catheters, yet is releasable so that one or both of the balloon catheters can be released from the linking device and maneuvered separately from the rest of the catheter system when desired. The method utilizes the described catheter system for stenting bifurcated vessels using a modified “kissing balloons” technique.Type: GrantFiled: January 4, 2010Date of Patent: August 19, 2014Assignee: MinvasysInventors: Pierre Hilaire, James J. Leary, Machiel Van Der Leest
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Publication number: 20100174352Abstract: Apparatus and methods are described for performing angioplasty and stenting with embolic protection. A catheter system includes an angioplasty balloon catheter, a balloon-expandable stent, an embolic protection device and a linking device. The catheter system has an undeployed configuration in which the balloon-expandable stent is mounted on the inflatable angioplasty balloon in an uninflated condition, the embolic protection member is positioned distally to the balloon-expandable stent and the angioplasty balloon, and the linking device is mounted on the catheter shaft of the angioplasty balloon catheter and the device shaft of the embolic protection device. The linking device prevents any relative longitudinal motion of the angioplasty balloon catheter and the embolic protection device, which might lead to accidental dislodgement of the balloon-expandable stent.Type: ApplicationFiled: March 27, 2008Publication date: July 8, 2010Applicant: MINVASYS, SAInventors: Machiel Van Der Leest, Pierre Hilaire
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Patent number: 7713296Abstract: A stenting system includes a stent delivery catheter having a catheter shaft with a step balloon mounted thereon. The step balloon has a proximal portion and a distal portion, wherein the proximal portion is inflatable to a larger expanded diameter than the distal portion. A two-part stent has a proximal part that is mounted on the proximal portion of the step balloon and a distal part that is mounted on the distal portion of the step balloon and a non-link zone between the proximal part and the distal part of the two-part stent. The proximal part and the distal part of the two-part stent are each configured with stent struts that extend like interdigitating fingers into the non-link zone to provide improved strut coverage in the carina region of the bifurcated vessel. The non-link zone effectively eliminates any difficulties in alignment of the two parts relative to one another during placement of the two-part stent in a bifurcated vessel.Type: GrantFiled: December 27, 2005Date of Patent: May 11, 2010Assignee: Minavasys, SAInventors: Pierre Hilaire, Machiel Van Der Leest
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Publication number: 20100106238Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis. The linking device allows the catheter system to be advanced as a unit and helps prevent premature or inadvertent dislodgement of the stent from the catheters, yet is releasable so that one or both of the balloon catheters can be released from the linking device and maneuvered separately from the rest of the catheter system when desired. The method utilizes the described catheter system for stenting bifurcated vessels using a modified “kissing balloons” technique.Type: ApplicationFiled: January 4, 2010Publication date: April 29, 2010Inventors: Pierre Hilaire, James J. Leary, Machiel Van Der Leest
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Publication number: 20100087908Abstract: The present invention relates to a catheter system of the type comprising: a stent delivery catheter (2) having a proximal end and a distal end and an interior lumen extending between the proximal end and the distal end; a stent (1) having a proximal end and a distal end and a stent lumen extending between the proximal end and the distal end, the stent having an expanded state and an unexpanded state; and an embolic protection filter (3) having an expanded state and an unexpanded state; the catheter system having a deployed position and an undeployed position. According to the invention the catheter system is characterised in that when the catheter system is in the undeployed position, the stent (1) is in its unexpanded state and positioned within the interior lumen of the stent delivery catheter (2) and the embolic protection filter (3) is in its unexpanded state and positioned within the stent lumen of the stent.Type: ApplicationFiled: March 20, 2008Publication date: April 8, 2010Inventors: Pierre Hilaire, Machiel Van Der Leest
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Patent number: 7645296Abstract: A catheter system is described for performing protected angioplasty and stenting of a patient's carotid bifurcation. A self-expanding stent is deployed across a stenosis in the patient's carotid artery. A catheter system that includes a rapid exchange angioplasty catheter with an occlusion balloon catheter positioned through the guidewire lumen is advanced through the guiding catheter to the distal end of the stent. A releasable linking device holds the catheter system together as a unit. The occlusion balloon is inflated within the stent to occlude the carotid artery and to prevent any embolic debris from traveling downstream from the treatment site. The angioplasty balloon is inflated to dilate the stenosis and to complete the expansion of the stent. The angioplasty catheter is withdrawn and any potential embolic debris is aspirated out through the lumen of the guiding catheter. The occlusion balloon is deflated and the catheter system is withdrawn.Type: GrantFiled: September 24, 2004Date of Patent: January 12, 2010Assignee: MinvasysInventors: Laurence Theron, Pierre Hilaire, Machiel van der Leest
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Patent number: 7641684Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis. The linking device allows the catheter system to be advanced as a unit and helps prevent premature or inadvertent dislodgement of the stent from the catheters, yet is releasable so that one or both of the balloon catheters can be released from the linking device and maneuvered separately from the rest of the catheter system when desired. The method utilizes the described catheter system for stenting bifurcated vessels using a modified “kissing balloons” technique.Type: GrantFiled: April 27, 2004Date of Patent: January 5, 2010Assignee: Minvasys, SAInventors: Pierre Hilaire, James J. Leary, Machiel Van Der Leest
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Publication number: 20090157160Abstract: Apparatus and methods are described for performing protected angioplasty and stenting of a patient's carotid bifurcation. An integrated catheter system can be configured in a rapid-exchange version or in an over-the-wire version. The catheter system includes a self-expanding stent, a stent delivery sheath, a combination angioplasty balloon catheter and stent pusher catheter, an embolic protection device and, in the rapid-exchange version, an auto-releasing sheath.Type: ApplicationFiled: September 19, 2006Publication date: June 18, 2009Inventors: Machiel Van Der Leest, Pierre Hilaire, Philippe Moulin, James Leary
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Patent number: 7335182Abstract: A valved connector apparatus is described having an integral opening and closing system operated by axial movement of the valve. The body of the valved connector apparatus is in a Y-shaped configuration with a main channel and a lateral channel branching off of the main channel. A normally dosed, passive hemostasis valve is housed in a valve body that is slidably connected to the proximal end of the main channel. The hemostasis valve is opened by sliding the valve body distally with respect to the Y-shaped connector body so that a cylindrical extension extending from the proximal end of the Y-shaped connector body penetrates a central opening in the hemostasis valve, creating an open passage for insertion of guidewires, catheters or other instruments. The valved connector apparatus allows safe introduction of extremely flexible or fragile guidewires, catheters or other instruments.Type: GrantFiled: September 27, 1999Date of Patent: February 26, 2008Assignee: ArthesysInventor: Pierre Hilaire
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Publication number: 20070282419Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis so that the catheter system can be advanced as a unit. The catheter system is combined with drug eluting technology to prevent restenosis, inflammation and/or thrombosis and/or to promote reendothelialization in the vessel bifurcation. The main vessel stent and/or the sidebranch stent may be coated or impregnated with one or more drugs or bioactive substances. Alternatively or in addition, the first balloon and/or the second balloon may be coated with or include a mechanism for delivering one or more drugs or bioactive substances to the vessel wall.Type: ApplicationFiled: April 23, 2007Publication date: December 6, 2007Applicant: MINVASYS, SAInventors: Pierre Hilaire, Machiel Van Der Leest
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Publication number: 20070250001Abstract: A guidewire separator device and methods are described for resolving guidewire entanglement and for introducing guidewires into branch vessels when performing angioplasty or stenting of a bifurcated artery. The device has an elongate tubular distal portion joined to an elongate proximal portion. A first lumen extends through the tubular distal portion of the device, with a first distal guidewire port located near a distal end of the distal portion and a first proximal guidewire port located near a proximal end of the distal portion. A second lumen extends through the tubular distal portion of the device, with a second distal guidewire port located near a distal end of the distal portion and a second proximal guidewire port located near a proximal end of the second lumen. One or both of the lumens may continue through the proximal portion of the device. Optionally, the device includes one or more longitudinal slits to externalize the guidewires from the lumens during withdrawal of device.Type: ApplicationFiled: May 21, 2005Publication date: October 25, 2007Inventors: Pierre Hilaire, Machiel Van Der Leest, Thierry Royer
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Publication number: 20060271152Abstract: A stenting system includes a stent delivery catheter having a catheter shaft with a step balloon mounted thereon. The step balloon has a proximal portion and a distal portion, wherein the proximal portion is inflatable to a larger expanded diameter than the distal portion. A two-part stent has a proximal part that is mounted on the proximal portion of the step balloon and a distal part that is mounted on the distal portion of the step balloon and a non-link zone between the proximal part and the distal part of the two-part stent. The proximal part and the distal part of the two-part stent are each configured with stent struts that extend like interdigitating fingers into the non-link zone to provide improved strut coverage in the carina region of the bifurcated vessel. The non-link zone effectively eliminates any difficulties in alignment of the two parts relative to one another during placement of the two-part stent in a bifurcated vessel.Type: ApplicationFiled: December 27, 2005Publication date: November 30, 2006Applicant: MINVASYS, SAInventors: Pierre Hilaire, Machiel Van Der Leest
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Publication number: 20050197688Abstract: A catheter system is described for performing protected angioplasty and stenting of a patient's carotid bifurcation. A self-expanding stent is deployed across a stenosis in the patient's carotid artery. A catheter system that includes a rapid exchange angioplasty catheter with an occlusion balloon catheter positioned through the guidewire lumen is advanced through the guiding catheter to the distal end of the stent. A releasable linking device holds the catheter system together as a unit. The occlusion balloon is inflated within the stent to occlude the carotid artery and to prevent any embolic debris from traveling downstream from the treatment site. The angioplasty balloon is inflated to dilate the stenosis and to complete the expansion of the stent. The angioplasty catheter is withdrawn and any potential embolic debris is aspirated out through the lumen of the guiding catheter. The occlusion balloon is deflated and the catheter system is withdrawn.Type: ApplicationFiled: September 24, 2004Publication date: September 8, 2005Applicant: MINVASYS, SAInventors: Laurence Theron, Pierre Hilaire, Machiel van der Leest
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Publication number: 20050085845Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis. The linking device allows the catheter system to be advanced as a unit and helps prevent premature or inadvertent dislodgement of the stent from the catheters, yet is releasable so that one or both of the balloon catheters can be released from the linking device and maneuvered separately from the rest of the catheter system when desired. The method utilizes the described catheter system for stenting bifurcated vessels using a modified “kissing balloons” technique.Type: ApplicationFiled: April 27, 2004Publication date: April 21, 2005Applicant: MINVASYS, SAInventors: Pierre Hilaire, James Leary, Machiel Van Der Leest
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Patent number: 6428557Abstract: Apparatus and methods are described for treating cardiovascular diseases with an embolization coil placement system utilizing an embolization coil and a pusher device. The embolization coil includes a releasable attachment assembly with a deformable ring-shaped member for connecting the embolization coil to a hydraulic pressure actuated coil release assembly on the pusher device. The coil release assembly includes a coil mounting wire with a bulbous distal portion that extends distally from a proximal tubular portion of the pusher device. A small inflatable balloon is mounted on the pusher device surrounding the coil mounting wire and fluidly connected to the proximal tubular portion. The embolization coil delivery system is prepared for use by crimping the deformable ring-shaped member around the deflated balloon member and the mounting wire. The bulbous distal portion of the mounting wire retains the crimped ring-shaped member on the pusher device.Type: GrantFiled: September 27, 1999Date of Patent: August 6, 2002Assignee: Arthesys, SAInventor: Pierre Hilaire
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Patent number: 6416543Abstract: An expandable tubular device is used as a stent for implantation in the lumen of a body duct, such as a blood vessel in particular, in order to ensure a passage therein, said device consisting of an assembly of tubular elements aligned along a common longitudinal axis and successively joined together in pairs by a plurality of linking members, each tubular element consisting of a strip forming a zigzag corrugation defining bent extreme portions which are successively connected together in pairs in opposite directions by rectilinear intermediate portions, the thickness (e) of said strip forming each of the above-mentions tubular elements (1), measured radially relative to said tubular element, being greater than the width 1 of this strip in said bent portions (2).Type: GrantFiled: March 6, 2000Date of Patent: July 9, 2002Assignee: CathNet-Science S.A.Inventors: Pierre Hilaire, Viviane Payrou
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Patent number: 6171279Abstract: The present invention relates to an “over-the-wire” dilatation catheter of the type comprising a flexible tubular body having a distal part, an intermediate part and a proximal part. According to the invention, the body comprises a core having a high modulus of elasticity, which core is permanently joined at one end to the proximal part and embedded at its other end in a wall defining an inner duct for a guide-wire to pass through. The invention finds a particular application in the treatment of stenoses of blood vessels.Type: GrantFiled: October 29, 1997Date of Patent: January 9, 2001Assignee: CathNet-Science S.A.Inventors: Pierre Hilaire, Philippe Salbert
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Patent number: 6059808Abstract: The subject of the present invention is an implantable device intended to reestablish or maintain the normal passage cross section of a bodily canal, of the type comprising an elongate framework which can expand radially between a first, contracted state of reduced diameter and a second, expanded state in which it has a diameter substantially equal to the natural diameter of said bodily canal and wherein said framework has, when contracted, at least one element consisting of a wire wound on itself, preferably with substantially constant pitch, along a substantially circular or helical directrix line.Type: GrantFiled: April 10, 1997Date of Patent: May 9, 2000Assignee: Laboratoires Nycomed SAInventors: Georges Boussignac, Pierre Hilaire