Patents by Inventor Pierre Hugon

Pierre Hugon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5266591
    Abstract: The compounds are ethanolamine benzoate compounds useful for the treatment of syndrome X, and of hypertension in patients who are insulin resistant or have one or more metabolic anomalies.A compound disclosed is S-1-(m-trifluoromethylphenyl)-2-{.beta.-{4-[2-(N-(3,3-diphenylpropionyl)am ino)ethyl] benzoyloxy}ethylamino} propane.
    Type: Grant
    Filed: November 20, 1992
    Date of Patent: November 30, 1993
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Pierre Hugon, Jacques Duhault, Michelle Boulanger, Francoise Lacour
  • Patent number: 5266718
    Abstract: New ethanolamine benzoate compounds which can be used as medicaments and correspond to the formula: ##STR1## wherein R is as defined in the description, in the form of racemic compounds and enantiomers. These new compounds and their physiologically tolerable salts can be used therapeutically for treatment of insulin-resistance states.
    Type: Grant
    Filed: June 12, 1992
    Date of Patent: November 30, 1993
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Pierre Hugon, Jacques Duhault, Francoise Lacour, Michelle Boulanger
  • Patent number: 5079245
    Abstract: The compounds 2-trifluoromethyl-7-substituted-6,7,8,9-tetrahydro-[5H]-benzocycloheptenes are disclosed and disclosed to be useful in the treatment of metabolic illnesses such as diabetes, obesity, and their complications. A perferred compound is 2-trifluoromethyl-7-amino-6,7,8,9-tetrahydro-[5H-benzocycloheptane.
    Type: Grant
    Filed: July 5, 1989
    Date of Patent: January 7, 1992
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Pierre Hugon, Jacques Duhault, Francoise Lacour
  • Patent number: 4711885
    Abstract: Triazole compounds of the formula: ##STR1## in which: X and X', which are the same or different, each represents hydrogen, halogen, trifluoromethyl, C.sub.1 -.sub.5 alkyl, or C.sub.1 -.sub.5 alkoxy, orX and X' together represent methylenedioxy,n is an integer of from 1 to 6,a is 0, 1 or 2;b is 0, 1, 2 or 3;c is 0, 1 or 2 andd is 2, 3, 4 or 5 such that a+b+c+d is equal to 4, 5, 6 or 7.These compounds and physiologically tolerable acid addition salts thereof may be used as medicines especially in the treatment of pain and anxiety.
    Type: Grant
    Filed: April 1, 1986
    Date of Patent: December 8, 1987
    Assignee: Adir et Compagnie
    Inventors: Michel Wierzbicki, Pierre Hugon, Jean-Claude Poignant
  • Patent number: 4505921
    Abstract: New sulfonylurea compounds of the formula: ##STR1## in which n is 1 or 2,R is thienyl, furyl, pyridyl or phenyl optionally mono or disubstituted,R.sub.1 and R.sub.2, the same or different, each are hydrogen, halogen, (C.sub.1 to C.sub.5)-alkyl, (C.sub.1 to C.sub.5)-alkoxy, or trifluoromethyl, or together represent --CH.sub.2 --O--CH.sub.2 --,R.sub.3 is hydrogen, or hydroxy, andR.sub.4 is (C.sub.1 to C.sub.5)-alkyl, (C.sub.3 to C.sub.8)-cycloalkyl or azacycloalkyl of the formula: ##STR2## in which p is zero or an integer from 1 to 5, or azabicycloalkyl of the formula: ##STR3## in which m is 1, 2, or 3. These new compounds and physiologically tolerable salts thereof may be used as medicines especially in the treatment of diabetes.
    Type: Grant
    Filed: September 6, 1983
    Date of Patent: March 19, 1985
    Assignee: ADIR, S.A.R.L.
    Inventors: Laszlo Beregi, Pierre Hugon, Jacques Duhault, Michelle Boulanger
  • Patent number: 4259335
    Abstract: 1-methyl-4-piperidinol esters of the formula: ##STR1## in which R is 7-chloro-4-quinolyl, 7-trifluoromethyl-4-quinolyl or 8-trifluoromethyl-4-quinolyl.These compounds and physiologically tolerable acid addition salts thereof may be used as medicines especially in the treatment of inflammatory processes and painful syndroms.
    Type: Grant
    Filed: August 6, 1979
    Date of Patent: March 31, 1981
    Assignee: Science Union et Cie, Societe Francaise de Recherche Medicale
    Inventors: Laszlo Beregi, Pierre Hugon, Jacques Bure, Francoise Degrand
  • Patent number: 4161529
    Abstract: Pyrrolidone derivatives of the formula: ##STR1## wherein R is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl,AndY is hydrogen, saturated or unsaturated hydrocarbon radical up to C.sub.4, hydroxyethyl, hydroxypropyl or carboxymethyl.These compounds are used as medicines especially in the treatment of lipid-metabolism disorders.
    Type: Grant
    Filed: February 14, 1978
    Date of Patent: July 17, 1979
    Assignee: Science Union et Cie, Societe Francaise de Recherche Medicale
    Inventors: Laszlo Beregi, Pierre Hugon, Jacques Duhault, Michelle Boulanger
  • Patent number: 4066662
    Abstract: Disubstituted azabicycloalkanes of the formula ##STR1## wherein: N IS 0, 1 OR 2R is saturated or unsaturated straight or branched (C.sub.1 -C.sub.5) aliphatic hydrocarbon, andX.sub.1, x.sub.2, x.sub.3, x.sub.4, x.sub.5, which are the same or different, are hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino or sulfamoyl.These compounds are used as medicine especially in the treatment of gastroduodenal ulcers, gastric hypersecretion, nauseous syndromes of central origin and hypertension.
    Type: Grant
    Filed: December 30, 1976
    Date of Patent: January 3, 1978
    Assignee: Science Union et Cie., Societe Francaise de Recherche Medicale
    Inventors: Laszlo Beregi, Pierre Hugon, Xavier Pascaud, Jean-Claude Poignant
  • Patent number: 4064245
    Abstract: Phenoxy compounds of the formula: ##STR1## wherein R and R', which are the same or different, are hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, trifluoromethyl, trifluoromethylthio, trifluoromethoxy, lower alkoxy-carbonyl or dimethylsulfamoyl.These compounds are used as medicines especially in the treatment of glucid -- and lipid -- metabolism disorders.
    Type: Grant
    Filed: July 14, 1976
    Date of Patent: December 20, 1977
    Assignee: Science Union et Cie, Societe Francaise de Recherche Medicale
    Inventors: Laszlo Beregi, Pierre Hugon, Jacques Duhault, Michelle Boulanger
  • Patent number: 4048321
    Abstract: Disubstituted azabicycloalkanes of the formula ##STR1## wherein: N IS 0, 1 OR 2R is saturated or unsaturated straight or branched (C.sub.1 -C.sub.5) aliphatic hydrocarbon, andX.sub.1, x.sub.2, x.sub.3, x.sub.4, x.sub.5, which are the same or different, are hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino or sulfamoyl.These compounds are used as medicine especially in the treatment of gastroduodenal ulcers, gastric hypersecretion, nauseous syndromes of central origin and hypertension.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: September 13, 1977
    Assignee: Science Union et Cie
    Inventors: Laszlo Beregi, Pierre Hugon, Xavier Pascaud, Jean-Claude Poignant
  • Patent number: 4042598
    Abstract: Disubstituted azabicycloalkanes of the formula ##STR1## wherein: N IS 0, 1 OR 2R is saturated or unsaturated straight or branched (C.sub.1 -C.sub.5) aliphatic hydrocarbon, andX.sub.1, x.sub.2, x.sub.3, x.sub.4, x.sub.5, which are the same or different, are hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino or sulfamoyl.These compounds are used as medicine especially in the treatment of gastroduodenal ulcers, gastric hypersecretion, nauseous syndromes of central origin and hypertension.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: August 16, 1977
    Assignee: Science Union et Cie, Societe Francaise de Recherche Medicale
    Inventors: Laszlo Beregi, Pierre Hugon, Xavier Pascaud, Jean-Claude Poignant
  • Patent number: 4032658
    Abstract: Alkanolamine derivatives and their optical isomers of the formula: ##STR1## wherein: N IS 2 OR 3, ANDR.sub.1 and R.sub.2 are lower alkyl or taken together with the nitrogen to which they are bonded, they form pyrrolidinyl, piperidino, dimethyl piperidino, morpholino, 1-thiomorpholino, azabicyclo [3, 3, 0] octyl or azabicyclo [3, 2, 2] nonyl.These compounds are used as medicines especially in the treatment of obesity, atheroma or metabolic diseases requiring weight reduction and regulation.
    Type: Grant
    Filed: April 23, 1975
    Date of Patent: June 28, 1977
    Assignee: Science-Union et Cie
    Inventors: Laszlo Beregi, Pierre Hugon, Jacques Duhault, Michelle Boulanger
  • Patent number: 3972994
    Abstract: Disubstituted azabicycloalkanes of the formula ##SPC1##Wherein:n is 0, 1 or 2R is saturated or unsaturated straight or branched (C.sub.1 -C.sub.5) aliphatic hydrocarbon, andX.sub.1, x.sub.2, x.sub.3, x.sub.4, x.sub.5, which are the same or different, are hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino or sulfamoyl.These compounds are used as medicine especially in the treatment of gastroduodenal ulcers, gastric hypersecretion, nauseous syndromes of central origin and hypertension.
    Type: Grant
    Filed: November 20, 1974
    Date of Patent: August 3, 1976
    Assignee: Science Union et Cie
    Inventors: Laszlo Beregi, Pierre Hugon, Xavier Pascaud, Jean-Claude Poignant
  • Patent number: 3956501
    Abstract: N-substituted glycinates of the formula: ##EQU1## optical isomers and acid addition salts thereof, wherein R is cyclopentyl, cyclohexyl, benzyl, halobenzyl, lower alkylbenzyl, lower alkoxybenzyl, methylenedioxybenzyl or trifluoromethylbenzyl.These compounds are used as medicines especially in the treatment of obesity or other metabolic diseases needing weight reduction and regulation.
    Type: Grant
    Filed: August 5, 1974
    Date of Patent: May 11, 1976
    Assignee: Science Union et Cie, Societe Francaise de Recherche Medical
    Inventors: Laszlo Beregi, Charles Malen, Pierre Hugon, Jacques Duhault