Patents by Inventor Pierre Jean F. Layrolle

Pierre Jean F. Layrolle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for applying a bioactive coating on a medical device
    Patent number: 6994883
    Abstract: The invention relates to the field of medical devices. More in particular, the invention relates to a method for coating by depositing inorganic ions and a bioactive agent to provide sterile medical devices, wherein said coating improves the biocompatibility and/or bioactivity of a medical device, such as an orthopedic or dental prosthesis. Furthermore, the invention relates to a medical device coated with a method according to the invention and to a reactor for use in a method according to the invention.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: February 7, 2006
    Assignee: IsoTis S.A.
    Inventors: Pierre Jean F. Layrolle, Martin Stigter, Klaas De Groot, Yuelian Liu
  • Proteinaceous coating
    Patent number: 6692790
    Abstract: The invention relates to a method for providing a proteinaceous coating on a medical implant, comprising the steps of: submersing the implant in a first aqueous solution comprising a protein and magnesium, calcium and phosphate ions through which a gaseous weak acid is passed; degassing the solution; allowing a coating to precipitate onto the implant; submersing the coated implant in a second solution to redissolve the magnesium, calcium and phosphate ions and to obtain the proteinaceous coating.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: February 17, 2004
    Assignee: Chienna B.V.
    Inventors: Yuelian Liu, Klaas de Groot, Pierre Jean F. Layrolle
  • Proteinaceous coating
    Publication number: 20030113438
    Abstract: The invention relates to a method for providing a proteinaceous coating on a medical implant, comprising the steps of: submersing the implant in a first aqueous solution comprising a protein and magnesium, calcium and phosphate ions through which a gaseous weak acid is passed; degassing the solution; allowing a coating to precipitate onto the implant; submersing the coated implant in a second solution to redissolve the magnesium, calcium and phosphate ions and to obtain the proteinaceous coating.
    Type: Application
    Filed: August 5, 2002
    Publication date: June 19, 2003
    Applicant: IsoTis N.V.
    Inventors: Yuelian Liu, Klaas de Groot, Pierre Jean F. Layrolle
  • Porous ceramic body
    Patent number: 6479418
    Abstract: The invention relates to a process for preparing a porous ceramic body, which process is based on a negative replica method. The invention further relates to a ceramic body obtainable by said method and to its use as a scaffold for tissue engineering.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: November 12, 2002
    Assignee: IsoTis N.V.
    Inventors: Shihong Li, Klaas de Groot, Pierre Jean F. Layrolle, Clemens Antoni van Blitterswijk, Joost Robert de Wijn
  • Porous ceramic body
    Publication number: 20020037799
    Abstract: The invention relates to a process for preparing a porous ceramic body, which process is based on a negative replica method. The invention further relates to a ceramic body obtainable by said method and to its use as a scaffold for tissue engineering.
    Type: Application
    Filed: December 15, 2000
    Publication date: March 28, 2002
    Inventors: Shihong Li, Klaas de Groot, Pierre Jean F. Layrolle, Clemens Antoni van Blitterswijk, Joost Robert de Wijn