Patents by Inventor Pierre Mangeney

Pierre Mangeney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Class of seco bis-indolic compounds which can be used as drugs and a process for the preparation thereof
    Patent number: 4347249
    Abstract: The invention relates to new chemical compounds.They are compounds corresponding to formula Ia. ##STR1## in which: R'.sub.3 represents a hydrogen atom or a hydroxy radical; R'.sub.5 represents a hydrogen atom or a hydroxy radical; or R'.sub.3 and R'.sub.5 together represent an epoxy bridge or a double bond; R".sub.5 represents a hydrogen atom or an ethyl radical; R'.sub.7 and R'.sub.8 are the same or different and represent a hydrogen atom or a methyl, hydroxymethylene, alkoxymethylene, aryloxymethylene, aminomethylene, monoalkyl or dialkyl aminomethylene, acylmethylene, arylaminomethylene, hydroxyethyl aminomethylene, alkylthiomethylene, aryloxythiomethylene or cyanomethylene radical; R.sub.1 represents a hydrogen atom or an alkyl, formyl or acyl radical: R.sub.2 represents a hydrogen atom or an alkoxy radical; R.sub.7 represents an alkanoyloxy radical, the broken line representing an optional double bond.These compounds can be used as drugs.
    Type: Grant
    Filed: July 9, 1980
    Date of Patent: August 31, 1982
    Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR)
    Inventors: Pierre Potier, Nicole Langlois, Yves Langlois, Ratremaniaina Z. Andriamialisoa, Pierre Mangeney
  • Nor bis-indole compounds usable as medicaments
    Patent number: 4307100
    Abstract: Compounds with antitumoral activity corresponding to the formula (I): ##STR1## wherein R'.sub.1 is a hydrogen atom or an alkoxy, acyl, formyl or haloacyl radical; R'.sub.2 is a hydrogen atom or an alkyl radical; R'.sub.3 and R".sub.3 are a hydrogen atom, hydroxyl radical or an alkanoyloxy radical, and together are a carbonyl group, and R'.sub.3 and R'.sub.5 together are an epoxy bridge or a double bond; R'.sub.4 is a hydrogen atom or an alkyloxycarbonyl, hydroxymethyl, alkanoyloxymethyl or acetamido radical; R'.sub.5 and R".sub.5 are a hydrogen atom or a hydroxyl, alkanoyloxyl, ethyl or 2-hydroxyethyl radical; R'.sub.6 is a hydrogen atom or an ethyl, 2-hydroxyethyl or acetyl radical; R.sub.1 is a hydrogen atom or an alkyl, formyl or acyl radical; R.sub.2 is a hydrogen atom or alkoxy radical; R.sub.3 is a hydrogen atom or a hydroxyl or alkanoyloxyl radical, and together with R.sub.4 is an epoxy bridge or a double bond; R.sub.4 is a hydrogen atom or a hydroxyl, alkanoyloxyl radical, and together with R.sub.
    Type: Grant
    Filed: August 20, 1979
    Date of Patent: December 22, 1981
    Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR)
    Inventors: Nicole Langlois, Yves Langlois, Ratremaniaina Z. Andriamialisoa, Pierre Potieo, Pierre Mangeney
  • Process for the synthesis of vinblastine and leurosidine
    Patent number: 4305875
    Abstract: The invention provides a process for the preparation of leurosidine or vinblastine, which comprises hydroxylating and reducing .DELTA..sup.
    Type: Grant
    Filed: December 5, 1979
    Date of Patent: December 15, 1981
    Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR)
    Inventors: Pierre Potier, Pierre Mangeney, Nicole Langlois, Yves Langlois