Patents by Inventor Pierre Marie Hendrik Frans DE Somer

Pierre Marie Hendrik Frans DE Somer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reactivation of interferon
    Patent number: 4017600
    Abstract: An aqueous interferon solution wherein the interferon has lost at least part of its initial activity is reactivated by treatment with a combination of (a) an agent for disrupting non-covalent bonds, (b) an agent for reducing disulfide bridges, and (c) an anionic or cationic surface-active agent. A heat-treatment is preferably added. Agent (a) is urea or guanidine-hydrochloride and agent (b) is mercaptoethanol or ethanethiol.
    Type: Grant
    Filed: April 3, 1975
    Date of Patent: April 12, 1977
    Inventors: William Edgar Stewart, Pierre Marie Hendrik Frans DE Somer
  • Stabilization of interferon
    Patent number: 3981991
    Abstract: An aqueous interferon solution is stabilized by treatment with a combination of (a) an agent for disrupting non-covalent bonds, (b) an agent for reducing disulfide bridges, and (c) an anionic or cationic surface-active agent.
    Type: Grant
    Filed: April 3, 1975
    Date of Patent: September 21, 1976
    Assignee: Stichting REGA V.Z.W.
    Inventors: William Edgar Stewart, Pierre Marie Hendrik Frans DE Somer