Patents by Inventor Pierre Marquet
Pierre Marquet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240017961Abstract: The present disclosure concerns an automated optical system for detection of a sanitary condition of a button, the system comprising a button housing defining a button-receiving cavity and comprising an inner side; a button disposed in the button-receiving cavity; an optical assembly to capture an optical signal of the button; a sanitary condition detection assembly to detect a predetermined sanitary condition of the button from information derived from the captured optical signal; and a disinfecting system for disinfecting the button. It also concerns a corresponding method.Type: ApplicationFiled: October 12, 2021Publication date: January 18, 2024Inventors: Raymond Boisvert, Pierre Marquet, Andre Villemaire
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Publication number: 20230411006Abstract: The area under the curve (AUC) of an immunosuppressant is the best exposure marker for following the global exposure to an immunosuppressant in an organ of a subject. However, measuring AUC is complicated in routine care as it requires multiple blood samples during the dosing interval, which can be expensive and clinically impractical. The present invention proposes to use artificial intelligence technique to predict AUC values based on the value of some predictors. Such method conducts to surprisingly accurate results. Notably, the method enables to obtain satisfactory results with only two samples.Type: ApplicationFiled: October 26, 2021Publication date: December 21, 2023Inventors: Jean-Baptiste WOILLARD, Pierre MARQUET
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Publication number: 20220091033Abstract: There is described a method for determining a refractive index of a medium. The method generally has providing a substrate having a surface, the surface having a first surface portion and a second surface portion spaced-apart from the first surface portion and recessed of a depth relative to the first surface portion; receiving the medium at least on the second surface portion; propagating a first optical beam towards the first surface portion and a second optical beam towards the second surface portion; collecting the first and second optical beams after said propagating and generating first and second signals being indicative of a phase of a respective one of the first and second collected optical beams; and determining a refractive index of said medium based on the first and second signals, the depth, a wavelength associated to the first and second optical beams and a refractive index of the substrate.Type: ApplicationFiled: January 30, 2020Publication date: March 24, 2022Inventors: Érik BELANGER, Pierre MARQUET, Bertrand DE DORLODOT, Réal VALLÉE
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Publication number: 20220081715Abstract: The invention relates to methods for diagnosing or determining in a subject who underwent a solid organ transplantation the risk of developing graft rejection other than T cell mediated, comprising the steps of: measuring in a peripheral blood sample from said subject the RNA expression levels of a set of genes comprising at least CXCL10, FCGR1A, FCGR1B and TEMP1; determining from the measured expression levels of said set of genes, an expression profile; comparing the determined expression profile of said subject with a reference expression profile; and determining from said comparison, whether said subject is experiencing said rejection or has an increased risk of developing said rejection.Type: ApplicationFiled: January 16, 2020Publication date: March 17, 2022Inventors: Maarten NAESENS, Elisabet VAN LOON, Pierre MARQUET, Wilfried GWINNER, Dany ANGLICHEAU, Marie ESSIG, Stephane GAZUT
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Publication number: 20200400685Abstract: The invention relates to biomarkers for typing or classifying allograft recipients as belonging to a transplant rejection group associated with antibody-mediated rejection (ABMR). The invention also provides for the treatment of typed allograft recipients suffering from antibody-mediated rejection by administration of an appropriate therapeutic agent.Type: ApplicationFiled: December 27, 2018Publication date: December 24, 2020Applicants: VITO NV, Medizinische Hochschule Hannover, Katholieke Universiteit Leuven, Institut National de La Sante et de la Recherche Medicale (INSERM), APHP - Assistance Publique - Hôpitaux Paris, University Hospital Center of Limoges, Medizinische Hochschule HannoverInventors: Inge Mertens, Hanny Willems, Maarten Naessens, Pierre Marquet, Dany Anglicheau, Marie Essig, Wilfried Gwinner
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Patent number: 10495627Abstract: An apparatus for measuring through optical means temporally resolved, optical properties, and/or phenotypes, linked to cellular homeostasis. Those temporal measurements enable the detection of cell regulation through various channels linked to homeostasis, in order to assess cell viability or early cell death through rapid diagnostic.Type: GrantFiled: May 5, 2016Date of Patent: December 3, 2019Assignee: LYNCEE TEC S.A.Inventors: Nicolas Pavillon, Jonas Kühn, Pascal Jourdain, Christian Depeursinge, Pierre Julius Magistretti, Pierre Marquet
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Publication number: 20160245787Abstract: An apparatus for measuring through optical means temporally resolved, optical properties, and/or phenotypes, linked to cellular homeostasis. Those temporal measurements enable the detection of cell regulation through various channels linked to homeostasis, in order to assess cell viability or early cell death through rapid diagnostic.Type: ApplicationFiled: May 5, 2016Publication date: August 25, 2016Inventors: Nicolas PAVILLON, Jonas KÜHN, Pascal JOURDAIN, Christian DEPEURSINGE, Pierre Julius MAGISTRETTI, Pierre MARQUET
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Patent number: 9360468Abstract: A method for measuring through optical means temporally resolved, optical properties, and/or phenotypes that are linked to cellular homeostasis. Those temporal measurements enable the detection of cell regulation through various channels linked to homeostasis, in order to monitor cell viability.Type: GrantFiled: August 16, 2011Date of Patent: June 7, 2016Assignee: LYNCEE TEC S.A.Inventors: Nicolas Pavillon, Jonas Kühn, Pascal Jourdain, Christian Depeursinge, Pierre Julius Magistretti, Pierre Marquet
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Patent number: 8885174Abstract: Apparatus and method are provided for monitoring and measuring matter and energy fluxes by use of devices able to detect refractive index changes. In one aspect, apparatus use an interference between two electromagnetic radiations in order to provide high sensitivity, enabling fluxes monitoring at the microscopic scale, by measuring phase changes or Optical Path Length (OPL) changes. In one aspect, methods are provided for monitoring and measuring the electrical activity of a biological cells, simultaneously on several cells, without use of electrodes and contrast agents.Type: GrantFiled: February 19, 2010Date of Patent: November 11, 2014Assignee: Lyncee Tec S.A.Inventors: Pascal Jourdain, Etienne Cuche, Christian Depeursinge, Pierre Julius Magistretti, Pierre Marquet
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Publication number: 20130210066Abstract: An apparatus for measuring through optical means temporally resolved, optical properties, and/or phenotypes, linked to cellular homeostasis. Those temporal measurements enable the detection of cell regulation through various channels linked to homeostasis, in order to assess cell viability or early cell death through rapid diagnostic.Type: ApplicationFiled: August 16, 2011Publication date: August 15, 2013Applicant: Lyncee Tec S.A.Inventors: Nicolas Pavillon, Jonas Kühn, Pascal Jourdain, Etienne Cuche, Christian Depeursinge, Pierre Julius Magistretti, Pierre Marquet
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Publication number: 20120038931Abstract: Apparatus and method are provided for monitoring and measuring matter and energy fluxes by use of devices able to detect refractive index changes. In one aspect, apparatus use an interference between two electromagnetic radiations in order to provide high sensitivity, enabling fluxes monitoring at the microscopic scale, by measuring phase changes or Optical Path Length (OPL) changes. In one aspect, methods are provided for monitoring and measuring the electrical activity of a biological cells, simultaneously on several cells, without use of electrodes and contrast agents.Type: ApplicationFiled: February 19, 2010Publication date: February 16, 2012Inventors: Pascal Jourdain, Etienne Cuche, Christian Depeursinge, Pierre Julius Magistretti, Pierre Marquet
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Patent number: 7649160Abstract: A new way of mixing instrumental and digital means is described for the general field of wave front sensing. The present invention describes the use, the definition and the utility of digital operators, called digital wave front operators (DWFO) or digital lenses (DL), specifically designed for the digital processing of wave fronts defined in amplitude and phase. DWFO are of particular interest for correcting undesired wave front deformations induced by instrumental defects or experimental errors. DWFO may be defined using a mathematical model, e.g. a polynomial function, which involves coefficients. The present invention describes automated and semi-automated procedures for calibrating or adjusting the values of these coefficients. These procedures are based on the fitting of mathematical models on reference data extracted from specific regions of a wave front called reference areas, which are characterized by the fact that specimen contributions are a priori known in reference areas.Type: GrantFiled: February 17, 2006Date of Patent: January 19, 2010Assignee: Lyncee Tec S.A.Inventors: Tristan Colomb, Etienne Cuche, Nicolas Aspert, Jonas Kuehn, Pierre Marquet, Christian Depeursinge, Frédéric Montfort, Florian Charriere, Anca Marian, Sébastien Bourquin, Yves Emery, Silvain Herminjard
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Publication number: 20080265130Abstract: A new way of mixing instrumental and digital means is described for the general field of wave front sensing. The present invention describes the use, the definition and the utility of digital operators, called digital wave front operators (DWFO) or digital lenses (DL), specifically designed for the digital processing of wave fronts defined in amplitude and phase. DWFO are of particular interest for correcting undesired wave front deformations induced by instrumental defects or experimental errors. DWFO may be defined using a mathematical model, e.g. a polynomial function, which involves coefficients. The present invention describes automated and semi-automated procedures for calibrating or adjusting the values of these coefficients. These procedures are based on the fitting of mathematical models on reference data extracted from specific regions of a wave front called reference areas, which are characterized by the fact that specimen contributions are a priori known in reference areas.Type: ApplicationFiled: February 17, 2006Publication date: October 30, 2008Inventors: Tristan Colomb, Etienne Cuche, Nicolas Aspert, Jonas Kuehn, Pierre Marquet, Christian Depeursinge, Frederic Montfront, Florian Charriere, Anca Marian, Sebastien Bourquin, Yves Emery, Silvain Herminjard
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Patent number: 6943924Abstract: The present invention is related to a method for performing digital holographic imaging (DHI), said DHI being characterized by the fact that images of a sample are obtained by applying numerical means to reconstruct holograms of the sample. In the method of the invention, the sample is in a medium with controlled properties that influence the behaviour of the sample, and/or that influence the process of hologram formation. The information content of one hologram, or of a plurality of holograms, recorded with the sample in one medium, or in a plurality of medium, is used to reconstruct one image of the sample, or a plurality of images of the sample, that describe quantitatively one property of the sample, or a plurality of properties of the sample. The present invention is also related to an apparatus with which to perform said method.Type: GrantFiled: December 4, 2002Date of Patent: September 13, 2005Assignees: Ecole Polytechnique Federale de Lausanne (EPFL), Universite de Lausanne /BRAInventors: Pierre Marquet, Etienne Cuche, Christian Depeursinge, Pierre Magistretti
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Publication number: 20050036181Abstract: The present invention is related to a method for performing digital holographic imaging (DHI), said DHI being characterized by the fact that images of a sample are obtained by applying numerical means to reconstruct holograms of the sample. In the method of the invention, the sample is in a medium with controlled properties that influence the behaviour of the sample, and/or that influence the process of hologram formation. The information content of one hologram, or of a plurality of holograms, recorded with the sample in one medium, or in a plurality of medium, is used to reconstruct one image of the sample, or a plurality of images of the sample, that describe quantitatively one property of the sample, or a plurality of properties of the sample. The present invention is also related to an apparatus with which to perform said method.Type: ApplicationFiled: December 4, 2002Publication date: February 17, 2005Inventors: Pierre Marquet, Etienne Cuche, Christian Depeursinge, Pierre Magistretti
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Patent number: 4731596Abstract: This highly reproducible stripline band-pass filter comprises, between its two leads (A and B), n halfwave resonators (1-7) connected in series. Suitable capacitors (C0-C7) provide a powerful coupling between the successive elements of the series circuit. Quarterwave resonators (10, 11, 70, 71) each having one end connected to the series circuit provide a steep-edge amplitude/frequency response at the limits of the pass-band of the hyperfrequency, wideband filter so obtained.Type: GrantFiled: February 26, 1986Date of Patent: March 15, 1988Assignee: Alcatel Thomson Faisceaux HertziensInventors: Jean-Claude Cruchon, Gilbert Prost, Jean-Pierre Marquet