Abstract: The invention relates to compositions and methods using a combination of at least one histidine or derivative thereof, at least one glycine or derivative thereof, and at least one additional agent selected from N-acetyl-cysteine, lysine, or arginine. An aspect of the invention is a method of promoting healthy fat metabolism and metabolic health in children at risk of developing insulin resistance and diabetes, promoting healthy lipolysis and use of fatty acid in metabolism, promoting healthy fat and adipocyte metabolism during puberty and adolescence, treating or preventing oxidative stress, a condition associated with oxidative stress, a reduced level of glutathione, or a condition associated with a reduced level of glutathione, by administering an effective amount of a combination of at least one glycine or derivative thereof, and lysine.

Abstract: A fan includes: a fan disc; an inter-blade platform including a base and a radial tab, a second orifice being formed in the tab of the platform; and a lock having a downstream edge configured to bear against the tab of the platform. The one among the downstream edge and the yoke of the fan disc includes a pin, the other includes a first orifice, the pin being configured to enter the first orifice and the second orifice so as to block the platform relative to the fan disc.

Abstract: Threaded tubular connection comprising a tubular female end extending from a main body of a first tubular member, and a tubular male end extending from a main body of a second tubular member, such that the tubular female end comprises a machined outer cylindrical surface close to the female free end having a first outer diameter and a second machined outer cylindrical surface above a threaded portion of the female end, a second outer diameter of the second outer cylindrical surface being bigger than the first outer diameter.

Abstract: Jacquard loom for producing a woven preform from several warp yarns and several weft yarns, the loom including a device for taking up the preform when it is being produced, in order to move it along an axis (X) as it is being formed, which axis is substantially parallel to a production direction for the preform, characterised in that the loom also includes a control for rotating the preform, substantially about the axis.

Abstract: A threaded tubular connection includes a box member having a female external thread, a female internal thread, and a female intermediate sealing surface between the female external thread and the female internal thread, and a pin member having a corresponding male external thread, a male internal thread, and a male intermediate sealing surface, such that male threads interlock by thread engagement with female threads, and intermediate sealing surfaces form an intermediate metal-to-metal seal when the threaded tubular connection is made up. The box member includes a minimal outer diameter at the intermediate metal-to-metal seal location, the minimal outer diameter being smaller than respectively an external and an internal outer diameter respectively being located above the female external thread and the female internal thread.

Abstract: The present invention relates to a method for determining a level of fat-free body mass (FFM) in a paediatric subject comprising determining a level of phenylacetylglutamine (PAG) in a sample obtained from the subject.

Abstract: The present invention generally relates to a method for predicting high blood level glucose in biofluid of a subject. Methods of improving glucose level management in an adolescent subject are also provided.

Abstract: A method for predicting the level of epicardial adipose tissue (EAT) in a subject comprising: (a) determining a level of one or more lipid biomarkers in a sample from the subject, wherein the biomarkers are selected from the following: (i) phosphatidylcholine (PC) [16:1/16:1] (ii) diacylglycerol (DAG) [42:8] (iii) phosphatidylethanolamine-ether (PE-O) [32:5] (iv) phosphatidylcholine (PC) [18:0/22:5] (v) phosphatidylinositol (PI) [18:0/16:1] (vi) phosphatidylglycerol (PG) [20:3/20:3] (vii) phosphatidylglycerol (PG) [22:5/18:1] (b) comparing the levels of the biomarkers in the sample to reference values; wherein the levels of the biomarkers in the sample compared to the reference values are indicative of levels of EAT fat in the subject.

Abstract: A threaded connection includes first and second tubular components, each including a respective male and female end. The male and female ends each include at least one threaded zone and finish in a terminal surface. The male threaded zone includes a first portion in which a width of teeth, CWTp, increases from a value CWTpmin corresponding to a width of a tooth closest to the terminal surface of the male end to a value CWTpmax corresponding to a width of a tooth furthest from the terminal surface. A width of teeth CWTb of the female threaded zone decreases from a value CWTbmax corresponding to a width of a tooth furthest from the terminal surface of the female end to a value CWTbmin corresponding to a width of a tooth closest to the terminal surface. The threaded zones cooperate in accordance with a self-locking make-up, with CWTpmin/CWTbmax?0.2 and CWTbmin/CWTpmax?CWTpmin/CWTbmax.

Abstract: A fan includes: a fan disc; an inter-blade platform including a base and a radial tab, a second orifice being formed in the tab of the platform; and a lock having a downstream edge configured to bear against the tab of the platform. The one among the downstream edge and the yoke of the fan disc includes a pin, the other includes a first orifice, the pin being configured to enter the first orifice and the second orifice so as to block the platform relative to the fan disc.

Abstract: A threaded tubular connection includes male and female threaded elements. The male threaded element includes outer and inner male threadings, a first outer peripheral surface disposed between the male threadings, a first male sealing surface on the outer peripheral surface, a second outer peripheral surface, a male axial abutment surface disposed at the end of the male threaded element, and a second male sealing surface provided on the second outer peripheral surface between the inner threading and the male axial abutment surface. The female threaded element includes outer and inner female threadings, an inner peripheral surface disposed between the female threadings, at least one first female sealing surface on the inner peripheral surface, a female axial abutment surface, and a second female sealing surface provided between the female axial abutment surface and the inner female threading. Threads of the male and female outer threadings are engaged in a coupled state.

Abstract: The present invention relates to a method for determining a level of fat-free body mass (FFM) in a paediatric subject comprising determining a level of phenylacetylglutamine (PAG) in a sample obtained from the subject.

Abstract: An assembly for producing a threaded connection, including tubular components provided with continuous threaded zones, in the form of helixes each provided with a first and a second taper generatrix, each of the threaded zones defining a thread profile, viewed in a longitudinal section passing through the axis of revolution, provided with load flanks, stabbing flanks, thread crests, and thread roots, wherein the height of the threads of the first threaded zones and the height of the threads of the second threaded zones are each in the range 1 mm to 2.5 mm, and the angle of the load flanks of the first and second threaded zones with the normal to the axis of revolution is in the range 1 to 20 degrees, and the angle of the stabbing flanks of the first and second threaded zones with the normal to the axis of revolution is in the range 3 to 25 degrees.

Abstract: An assembly producing a threaded connection, including first and second tubular components with an axis of revolution and each respectively including at one end at least a first continuous threaded zone following a first helix on an outer or inner circumferential surface depending on whether the threaded end is male or female in type, and configured to cooperate together upon makeup. The first threaded zones of the ends include a variable width dovetail thread profile, the ends respectively finishing in a terminal surface. At least one of the ends include a lip provided between the threaded zone and the terminal surface, the lip carrying a sealing surface configured to cooperate in a sealing interference fit with a corresponding sealing surface disposed facing the other end when the connection is in the made-up state. The lip is hollowed out by a groove adjoining the threaded zone and the sealing surface.

Abstract: The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to a new biomarker, its use and a method that allows it to diagnose the likelihood to resist diet induced weight gain, and/or to be susceptible to a diet induced weight gain. For example, the biomarker may be trimethylamine-N-oxide.

Abstract: A threaded tubular connection includes male and female threaded elements. The male threaded element includes outer and inner male threadings, a first outer peripheral surface disposed between the male threadings, a first male sealing surface on the outer peripheral surface, a second outer peripheral surface, a male axial abutment surface disposed at the end of the male threaded element, and a second male sealing surface provided on the second outer peripheral surface between the inner threading and the male axial abutment surface. The female threaded element includes outer and inner female threadings, an inner peripheral surface disposed between the female threadings, at least one first female sealing surface on the inner peripheral surface, a female axial abutment surface, and a second female sealing surface provided between the female axial abutment surface and the inner female threading. Threads of the male and female outer threadings are engaged in a coupled state.

Abstract: Jacquard loom (100) for producing a woven preform (102) from a plurality of warp yarns and a plurality of weft yarns, said loom comprising a device (106) for taking up the preform when it is being produced, in order to move it along an axis (X) as it is being formed, which axis is substantially parallel to a production direction for the preform, characterised in that said loom also comprises means (105) for rotating the preform, substantially about said axis.

Abstract: The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to trimethylamine as a biomarker in urine of the efficacy of prebiotics for the prevention of diet induced weight gain.

Abstract: The invention relates to a method, a system and kit for identifying the sample of a patient having IBD or predicting the relapse of IBD in patients based on the measurement of biomarkers in a sample of the patient. The biomarkers can be lipids or amino acids or a combination thereof.

Abstract: Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort including centenarians, elderly and young adults. The inventors have identified biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose a method of diagnosing a lifestyle that allows delaying and/or avoiding ageing related chronic inflammatory disorders using 9-oxo-ODE as biomarker.