Patents by Inventor Pierre N. Floriano
Pierre N. Floriano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9709580Abstract: A bio-nano-chip (BNC) technology that works in connection with non-invasive samples, such as saliva, cheek swab or urine samples that can be easily performed by non-specialists, such as security personnel and police officers is disclosed. The microfluidic system for drug testing includes an analyzer or reader having a housing containing a slot for receiving a cartridge, a drug testing cartridge, a processor having a user interface, an optical or energy sensing means, and a means for moving fluid.Type: GrantFiled: March 21, 2012Date of Patent: July 18, 2017Assignee: William Marsh Rice UniversityInventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Glennon Simmons
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Patent number: 9671413Abstract: The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents in disposable cassettes or lab cards for use as analyzers, as well as software to evaluate and report test results. The system promises to improve point of care in vitro diagnostics.Type: GrantFiled: November 11, 2011Date of Patent: June 6, 2017Assignees: William Marsh Rice University, Board of Regents of the University of Texas SystemInventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Ian Thompson
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Patent number: 9535068Abstract: A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.Type: GrantFiled: November 11, 2011Date of Patent: January 3, 2017Assignee: William Marsh Rice UniversityInventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Martin Thornhill, Spencer Redding, Nadarajah Vigneswaran, Craig Murdoch, Paul Speight
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Patent number: 9248448Abstract: A bionanochip cartridge for analysis of multiple samples or analytes is provided herein, and the cartridge is dimensioned to take advantage of existing robotic microtiter plate handling equipment. Fluidics are specially designed to provide a small footprint and to prevent cross contamination.Type: GrantFiled: April 22, 2014Date of Patent: February 2, 2016Assignee: William Marsh Rice UniversityInventors: John McDevitt, Nicolaos Christodoulidies, Pierre N. Floriano, Tim Abram
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Publication number: 20140322103Abstract: A bionanochip cartridge for analysis of multiple samples or analytes is provided herein, and the cartridge is dimensioned to take advantage of existing robotic microtiter plate handling equipment. Fluidics are specially designed to provide a small footprint and to prevent cross contamination.Type: ApplicationFiled: April 22, 2014Publication date: October 30, 2014Applicant: William Marsh Rice UniversityInventors: John MCDEVITT, Nicolaos CHRISTODOULIDIES, Pierre N. FLORIANO, Tim ABRAM
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Publication number: 20140235487Abstract: Neural net method of computing oral cancer risk based on inputs such as age, gender, smoking status, morphological characteristics of sampled cells, and levels of biomarkers in samples cells.Type: ApplicationFiled: April 25, 2014Publication date: August 21, 2014Applicant: William Marsh Rice UniversityInventors: John T. McDevitt, Pierre N. FLORIANO, Tim ABRAM
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Publication number: 20140094391Abstract: A bio-nano-chip (BNC) technology that works in connection with non-invasive samples, such as saliva, cheek swab or urine samples that can be easily performed by non-specialists, such as security personnel and police officers is disclosed. The microfluidic system for drug testing includes an analyzer or reader having a housing containing a slot for receiving a cartridge, a drug testing cartridge, a processor having a user interface, an optical or energy sensing means, and a means for moving fluid.Type: ApplicationFiled: March 21, 2012Publication date: April 3, 2014Applicant: WILLIAM MARSH RICE UNIVERSITYInventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Glennon Simmons
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Publication number: 20130295580Abstract: A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.Type: ApplicationFiled: November 11, 2011Publication date: November 7, 2013Applicants: William Marsh Rice University, University of Sheffield, The Board of Regents of the University of Texas SystemInventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Martin Thornhill, Spencer Redding, Nadarajah Vigneswaran, Craig Murdoch, Paul Speight
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Publication number: 20130274136Abstract: The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents in disposable cassettes or lab cards for use as analyzers, as well as software to evaluate and report test results. The system promises to improve point of care in vitro diagnostics.Type: ApplicationFiled: November 11, 2011Publication date: October 17, 2013Applicants: UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER, WILLIAM MARSH RICE UNIVERSITYInventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Ian Thompson
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Publication number: 20130130933Abstract: This invention generally relates to the use of devices to measure and assess the level of biomarkers that are indicative of the general wellness of an individual and methods of correlating such information into a wellness index.Type: ApplicationFiled: August 11, 2011Publication date: May 23, 2013Applicant: WILLIAM MARSH RICE UNIVERSITYInventors: John T McDevitt, Pierre N. Floriano, Nicolaos Christodoullides, Glennon Simmons
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Patent number: 8377398Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.Type: GrantFiled: May 31, 2006Date of Patent: February 19, 2013Assignees: The Board of Regents of The University of Texas System, LabNow, Inc.Inventors: John T. McDevitt, Nicolaos J. Christodoulides, Pierre N. Floriano, Gary N. Douglas, Patrick E. Rogers
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Publication number: 20120322682Abstract: A panel of biomarkers for diagnosis, monitoring of progression and prognosis of various brain injuries and PTSD.Type: ApplicationFiled: June 19, 2012Publication date: December 20, 2012Applicant: WILLIAM MARSH RICE UNIVERSITYInventors: John MCDEVITT, Nicolaos CHRISTODOULIDES, Pierre N. FLORIANO
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Publication number: 20120208715Abstract: Embodiments of the invention utilizes advanced detection methodologies, such as the lab-on-a-chip (LOC) technology, as a cost-effective, efficient, ultra-sensitive rapid method for diagnosing Acute Myocardial Infarction (AMI) in human subjects. In certain aspects, multiple biomarkers of AMI are concurrently detected and measured in serum and saliva to provide a more efficient, sensitive and accurate diagnosis of AMI.Type: ApplicationFiled: August 20, 2010Publication date: August 16, 2012Inventors: John T. McDevitt, Craig S. Miller, Jeffrey L. Ebersole, Nicolaos Christodoulides, Pierre N. Floriano
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Patent number: 8105849Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.Type: GrantFiled: December 22, 2004Date of Patent: January 31, 2012Assignee: Board of Regents, The University of Texas SystemInventors: John T. McDevitt, Karri L. Ballard, Pierre N. Floriano, Nick J. Christodoulides, Dean Neikirk, Eric Anslyn, Jason Shear
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Patent number: 8101431Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.Type: GrantFiled: December 22, 2004Date of Patent: January 24, 2012Assignee: Board of Regents, The University of Texas SystemInventors: John T. McDevitt, Karri L. Ballard, Pierre N. Floriano, Nick J. Christodoulides, Dean Neikirk, Eric Anslyn, Jason Shear
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Publication number: 20100291588Abstract: Methods, systems, and apparatus for detecting the presence of analytes are described. A fluid or gas sample may pass through a microsieve-based detection system and/or a particle-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the identity and quantity of the captured analytes.Type: ApplicationFiled: June 23, 2006Publication date: November 18, 2010Applicant: The Board of Regents of the University of Texas SystemInventors: John T. McDevitt, Karri Ballard, Nicolaos J. Christodoulides, Pierre N. Floriano, Glennon W. Simmons
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Publication number: 20090215072Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.Type: ApplicationFiled: May 31, 2006Publication date: August 27, 2009Inventors: John T. McDevitt, Nicolaos J. Christodoulides, Pierre N. Floriano, Gary N. Douglas, Patrick E. Rogers
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Publication number: 20080300798Abstract: Embodiments of the invention include methods by which cardiac biomarkers are assigned an index (cardiovascular biomarker index-cardiobioindex, CBI) as a means to describe the utility of each biomarker, or combination of biomarkers for risk evaluation, diagnosis or prognosis of cardiovascular disease status.Type: ApplicationFiled: April 16, 2008Publication date: December 4, 2008Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Craig S. Miller, Jeffrey L. Ebersole
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Publication number: 20080176253Abstract: Methods, systems, and apparatus for detecting the presence of human or animal immunoglobin-E are described. A fluid or gas sample may pass through a particle-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the identity and quantity of the captured IgE.Type: ApplicationFiled: May 10, 2007Publication date: July 24, 2008Inventors: Nicolaos Christodoulides, Pierre N. Floriano, Karri Ballard, John T. McDevitt