Patents by Inventor Pierre R. Leblanc

Pierre R. Leblanc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOTHERAPIES EMPLOYING SELF-ASSEMBLING VACCINES
    Publication number: 20230192828
    Abstract: Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to four biotinylated components, and further wherein at least two of the four biotinylated components are not identical.
    Type: Application
    Filed: September 7, 2022
    Publication date: June 22, 2023
    Inventors: Jeffrey A. Gelfand, Mark C. Poznansky, Pierre R. LeBlanc, Svetlana E. Korochkina
  • SELF-ASSEMBLED VACCINES AND COMBINATION THERAPIES FOR TREATING CANCER
    Publication number: 20220273780
    Abstract: Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to a biotinylated component (e.g., tumor cell, tumor antigen, virus or viral antigen). The self-assembling pharmaceutical compositions may further comprise an immunotherapy (e.g., anti-PD-1 antibody). In addition, methods of using these pharmaceutical compositions to prevent and/or treat cancer, or to induce an immune response are provided. Methods of using the self-assembling pharmaceutical compositions in combination with an immunotherapy (e.g., anti-PD-1 antibody) are also provided.
    Type: Application
    Filed: July 17, 2020
    Publication date: September 1, 2022
    Inventors: Mark C. Poznansky, Jeffrey A. Gelfand, Pierre R. LeBlanc, Svetlana E. Korochkina
  • IMMUNOTHERAPIES EMPLOYING SELF-ASSEMBLING VACCINES
    Publication number: 20210179697
    Abstract: Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to four biotinylated components, and further wherein at least two of the four biotinylated components are not identical.
    Type: Application
    Filed: August 28, 2020
    Publication date: June 17, 2021
    Inventors: Jeffrey A. Gelfand, Mark C. Poznansky, Pierre r. LeBlanc, Svetlana E. Korochkina
  • Immunotherapies employing self-assembling vaccines
    Patent number: 10800837
    Abstract: Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to four biotinylated components, and further wherein at least two of the four biotinylated components are not identical.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: October 13, 2020
    Assignee: The General Hospital Corporation
    Inventors: Jeffrey A. Gelfand, Mark C. Poznansky, Pierre R. Leblanc, Svetlana E. Korochkina
  • IMMUNOTHERAPIES EMPLOYING SELF-ASSEMBLING VACCINES
    Publication number: 20190135902
    Abstract: Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to four biotinylated components, and further wherein at least two of the four biotinylated components are not identical.
    Type: Application
    Filed: December 5, 2016
    Publication date: May 9, 2019
    Applicant: The General Hospital Corporation
    Inventors: Jeffrey A. Gelfand, Mark C. Poznansky, Pierre R. Leblanc, Svetlana E. Korochkina
  • Immunotherapies employing self-assembling vaccines
    Patent number: 9527906
    Abstract: Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to four biotinylated components, and further wherein at least two of the four biotinylated components are not identical.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: December 27, 2016
    Assignee: The General Hospital Corporation
    Inventors: Jeffrey A. Gelfand, Mark C. Poznansky, Pierre R. Leblanc, Svetlana E. Korochkina
  • IMMUNOTHERAPIES EMPLOYING SELF-ASSEMBLING VACCINES
    Publication number: 20110129484
    Abstract: Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to four biotinylated components, and further wherein at least two of the four biotinylated components are not identical.
    Type: Application
    Filed: April 17, 2009
    Publication date: June 2, 2011
    Inventors: Jeffrey A. Gelfand, Mark C. Poznansky, Pierre R. Leblanc, Svetlana E. Korochkina