Abstract: The present invention relates to the field of muscle regeneration, and more particularly to the replenishment of the in vivo muscle stem cells pool. It more specifically relates to a 5-hydroxytryptamine B1 receptor-stimulating agent, and to a composition comprising said agent, for use as i) a promoter of satellite cells self-renewal and/or differentiation, and/or ii) an agent preventing and/or inhibiting the satellite cells pool exhaustion. The invention further encompasses therapeutic and screening methods.

Abstract: The present invention relates to the field of regenerative medicine, and more particularly to the improvement of the in vivo engraftment potential of biological material to be administered to a subject in need thereof.

Abstract: The present invention relates to the field of regenerative medicine, and more particularly to the improvement of the in vivo engraftment potential of biological material to be administered to a subject in need thereof.

Abstract: The present invention relates to the long-term preservation of biological material. More specifically, it concerns a preservation container comprising: a biological container for containing biological material, a first shield configured for absorbing gamma-rays, a second shield configured for absorbing ambient neutrons, said second shield surrounding the biological container, the preservation container being of low-radioactivity background materials, and a method for preserving a biological material, comprising: a) providing a biological material in a confinement container, b) providing the preservation container of the invention, c) placing the confinement container containing the biological material into said preservation container, d) storing said preservation container containing the biological material in a room located under a material attenuating cosmic rays and induced particles, said material having a thickness equivalent to 1 m to 7000 m of water, for attenuating cosmic rays.

Abstract: The present invention refers to micro-fragmented fat or a composition comprising micro-fragmented fat for use in the treatment of a systemic disease, preferably associated to or caused by sepsis. Moreover, the micro-fragmented fat or the composition comprising micro-fragmented fat is used for treating a systemic, inflammatory, immune, or chronic disease, said disease being intended as a consequence of septic disease. Preferably, the micro-fragmented fat is useful for treating both the acute (early) and late stages of sepsis.

Abstract: The present invention relates to the field of muscle regeneration, and more particularly to the replenishment of the in vivo muscle stem cells pool. It more specifically relates to a 5-hydroxytryptamine B1 receptor-stimulating agent, and to a composition comprising said agent, for use as i) a promoter of satellite cells self-renewal and/or differentiation, and/or ii) an agent preventing and/or inhibiting the satellite cells pool exhaustion. The invention further encompasses therapeutic and screening methods.

Abstract: The present invention relates to the field of muscle regeneration, and more particularly to the replenishment of the in vivo muscle stem cells pool. It more specifically relates to a 5-hydroxytryptamine B1 receptor-stimulating agent, and to a composition comprising said agent, for use as i) a promoter of satellite cells self-renewal and/or differentiation, and/or ii) an agent preventing and/or inhibiting the satellite cells pool exhaustion. The invention further encompasses therapeutic and screening methods.

Abstract: The present invention relates to the field of skin and/or hair repair, for therapeutic and cosmetic purposes. It more specifically relates to an agent stimulating the 5-hydroxytryptamine 1B receptor, for use for boosting skin and/or hair repair.

Abstract: The present invention relates to the field of regenerative medicine, and more particularly to the improvement of the in vivo engraftment potential of biological material to be administered to a subject in need thereof.

Abstract: The present invention relates to the field of myocardial infraction (MI). It more specifically relates to an agent stimulating, either directly or indirectly, the 5-hydroxytryptamine 1B receptor, and to a composition comprising said agent, for use in the treatment of a patient having a myocardial infraction (MI). The invention further encompasses therapeutic and screening methods.

Abstract: The present invention relates to the field of muscle regeneration, and more particularly to the replenishment of the in vivo muscle stem cells pool. It more specifically relates to a 5-hydroxytryptamine B1 receptor-stimulating agent, and to a composition comprising said agent, for use as i) a promoter of satellite cells self-renewal and/or differentiation, and/or ii) an agent preventing and/or inhibiting the satellite cells pool exhaustion. The invention further encompasses therapeutic and screening methods.

Abstract: In a system for coupling a toothed starter ring to a support connected to the output shaft of an internal combustion engine, a complementary substantially cylindrical peripheral surface of the ring is fixed over at least a part of its extent to a substantially cylindrical peripheral surface of the support in such a manner that the ring can deform slightly in the radial direction toward the shaft to reduce the maximum stresses exerted on the ring during a starting operation.

Abstract: In a system for coupling a toothed starter ring to a support connected to the output shaft of an internal combustion engine, a complementary substantially cylindrical peripheral surface of the ring is fixed over at least a part of its extent to a substantially cylindrical peripheral surface of the support in such a manner that the ring can deform slightly in the radial direction toward the shaft to reduce the maximum stresses exerted on the ring during a starting operation.