Patents by Inventor Pierre Roger

Pierre Roger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020137740
    Abstract: The subject of the invention is the compounds of formula: 1
    Type: Application
    Filed: November 15, 2001
    Publication date: September 26, 2002
    Inventors: Evelyne Fontaine, Danielle Gully, Pierre Roger, Camille Georges Wermuth
  • Publication number: 20020128170
    Abstract: A liquid rinse-added fabric care composition that is characterized by at least two visually distinct phases when the composition is at rest and wherein at least one of the phases contains a fabric care agent is provided. The composition forms a temporary mixture when shaken that allows a consumer to dose a representative sample of the composition and spontaneously re-forms at least two visually distinct phases when allowed to remain at rest. The fabric care agents present in one or more phases of the composition may include fabric softener actives, color care agents, perfumes, antibacterial agents, malodor control agents, ultraviolet protection agents, anti-abrasion, anti-wear & fabric integrity agents, wrinkle control agents, and mixtures thereof. The composition should also contain less than about 5%, preferably less than about 3%, and even more preferably less than about 1% by weight of detergent actives.
    Type: Application
    Filed: June 19, 2001
    Publication date: September 12, 2002
    Inventors: Marc Johan DeClercq, Hugo Jean Marie DeMeyere, Serge Gabriel Pierre Roger Cauwberghs, Kristine Janssens, Franciscus Joseph Madeleine DeBlock, Johan Maurice Theo DePootere, Kimiko Fukushima, Akiko Taneko
  • Patent number: 6344470
    Abstract: The subject of the invention is the compounds of formula: in which R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. The compounds have a high affinity for CRF receptors.
    Type: Grant
    Filed: April 2, 1999
    Date of Patent: February 5, 2002
    Assignee: Sanofi-Synthelabo
    Inventors: Evelyne Fontaine, Danielle Gully, Pierre Roger, Camille Georges Wermuth
  • Patent number: 5880135
    Abstract: A compound, as well as its stereoisomers and addition salts, possssing antagonist activity with respect to corticotropin releasing hormone (CRF) has the formula: ##STR1## in which R.sub.1, and R.sub.21 which are identical or different, are independently selected from a halogen atom; a (C.sub.1 -C.sub.5)hydroxyalkyl radical; a (C.sub.1 -C.sub.5)alkyl; a (C.sub.7 -C.sub.10)aralkyl; a (C.sub.1 -C.sub.5)alkoxy; a trifluoromethyl; a nitro; a nitrile; an --SR group in which R is selected from hydrogen, a (C.sub.1 -C.sub.5)alkyl radical and a (C.sub.7 -C.sub.10)aralkyl radical; an --S--CO--R group in which R is selected from a (C.sub.1 -C.sub.5)alkyl radical and an aralkyl radical in which the aryl part is (C.sub.6 -C.sub.8) and the alkyl part is (C.sub.1 -C.sub.4); a --COOR' group in which R' is selected from hydrogen and a (C.sub.1 -C.sub.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: March 9, 1999
    Assignee: Sanofi
    Inventors: Danielle Gully, Pierre Roger, Camille Georges Wermuth
  • Patent number: 5464847
    Abstract: The invention relates to the derivatives of formula I: ##STR1## in which R.sub.1 represents a phenyl or naphthyl radical (optionally substituted), R.sub.2 represents a hydrogen or halogen atom or an alkyl, hydroxymethyl or formyl radical, R.sub.3 represents an alkyl, cycloalkyl, alkenyl, cycloalkylalkyl or phenyl radical, R.sub.4 represents a hydrogen atom or an alkyl, cycloalkyl or cycloalkylalkyl radical, R.sub.5 represents an alkyl, cycloalkyl, cycloalkylalkyl or alkenyl radical or a radical of formula B: ##STR2## (p=0, 1, 2 or 3), R.sub.6 represents a phenyl, pyridyl, imidazolyl, pyrrolyl, thienyl or furyl radical, optionally substituted, or a cycloalkyl radical,m and n, which may be identical or different, each represent 0 or 1,their possible stereoisomers and their addition salts.
    Type: Grant
    Filed: June 23, 1993
    Date of Patent: November 7, 1995
    Assignee: Elf Sanofi
    Inventors: Gilles Courtemanche, Claudie Gautier, Danielle Gully, Pierre Roger, Gerard Valette, Camille G. Wermuth
  • Patent number: 5449253
    Abstract: The tube is hammered by means of a hydraulic or an electromagnetic hammer pressed against a pile-driving head situated at the bottom of the tube. The bottom of the tube is preferably provided with a hammering bearing surface and a removable head is used that is suitable for resisting laterally on said bearing surface. The invention is particularly applicable to providing piles or stakes, particularly for a foundation.
    Type: Grant
    Filed: July 30, 1993
    Date of Patent: September 12, 1995
    Assignee: Bouygues Offshore
    Inventor: Pierre Roger
  • Patent number: 4983726
    Abstract: The invention relates to nitrosourea derivatives, a process for their preparation and pharmaceutical compositions containing them.The nitrosourea derivatives of the invention correspond to the following formula (I): ##STR1## in which: R can represent a hydrogen atom or an alkyl group from 1 to 30 carbon atoms, X represents a hydroxy group or an -NR.sub.1 R.sub.2 group, Y represents a hydrogen atom, a hydroxy group or an -NR'.sub.1 R'.sub.2 group, where R.sub.1 and/or R'.sub.1 each represent a hydrogen atom or a ##STR2## group, Hal being a halogen, and R.sub.2 and/or R'.sub.2 can each represent a hydrogen atom or an alkyl group comprising from 1 to 6 carbon atoms, R' and R" can represent hydrogen or OH, provided that at least X represents ##STR3## with R.sub.1 representing ##STR4## or Y represents ##STR5## with R'.sub.1 representing ##STR6## and provided that either R' represents hydrogen or R" represents hydrogen, and R' and R" cannot be simultaneously hydrogen atoms.
    Type: Grant
    Filed: November 24, 1989
    Date of Patent: January 8, 1991
    Assignee: Sanofi S.A.
    Inventors: Pierre Roger, Patrick Choay, Claude Monneret, Jean-Paul Fournier
  • Patent number: 4980349
    Abstract: The invention relates to new compounds corresponding to formula I: ##STR1## in which: W represents C=O, CH.sub.2 or CHOH,Z represents ##STR2## R.sub.1 and R.sub.2 represent especially Cl or F, R, R' and R" represent especially H,X represents especially CH.sub.2,Y represents especially COOH,u and v are two integers ranging from 0 to 10,p and q take the value 0 or 1,n and m are two integers ranging 0 to 10 andt is 0 or 1the total number of carbon atoms in the chain ##STR3## ranging from 2 to 20, and to their physiologically acceptable salts obtained with organic or inorganic acids.These compounds are useful for preparing medicinal products which have, especially, anti-inflammatory properties.
    Type: Grant
    Filed: November 12, 1987
    Date of Patent: December 25, 1990
    Assignee: SANOFI
    Inventors: Pierre Roger, Jean-Paul Fournier, Alain Martin, Jean Choay
  • Patent number: 4902791
    Abstract: The invention relates to nitrosourea derivatives, a process for their preparation and pharmaceutical compositions containing them.The nitrosourea derivatives of the invention correspond to the following formula (I): ##STR1## in which: R can represent a hydrogen atom or an alkyl group from 1 to 30 carbon atoms, X represents a hydroxy group or an --NR.sub.1 R.sub.2 group, Y represents a hydrogen atom, a hydroxy group or an --NR'.sub.1 R'.sub.2 group, where R.sub.1 and/or R'.sub.1 each represent a hydrogen atom or a ##STR2## group, Hal being a halogen, and R.sub.2 and/or R'.sub.2 can each represent a hydrogen atom or an alkyl group comprising from 1 to 6 carbon atoms, R' and R" can represent hydrogen or OH, provided that at least X represents ##STR3## with R.sub.1 representing ##STR4## or Y represents ##STR5## with R'.sub.1 representing ##STR6## and provided that either R' represents hydrogen or R" represents hydrogen, and R' and R" cannot be simultaneously hydrogen atoms.
    Type: Grant
    Filed: April 14, 1988
    Date of Patent: February 20, 1990
    Assignee: Sanofi S.A.
    Inventors: Pierre Roger, Patrick Choay, Claude Monneret, Jean-Paul Fournier, Alain Martin
  • Patent number: 4883903
    Abstract: The subject of the invention is a novel procedure for the preparation of the compounds of formula I: ##STR1## in which n varies in particular from 2 to 5 and R represents Cl, Br or FZ represents in particular hydrogen, characterized in that the halogenoformate of formula II: ##STR2## R and n having the meanings indicated above, Y representing a halogen, is made to react with NH.sub.2 CH.sub.2 CH.sub.2 Cl to form the compound of formula Ia: ##STR3## in which R has the meanings indicated above, and in that the compound Ia is treated directly with nitrosylsulfuric acid.
    Type: Grant
    Filed: April 22, 1988
    Date of Patent: November 28, 1989
    Assignee: Sanofi
    Inventors: Pierre Roger, Jean-Paul Fournier, Rolande Leroy
  • Patent number: 4871843
    Abstract: The invention relates to new N-cyclic benzenesulfonamides, their process of preparation and their use as active substance of pharmaceutical compositions. The new benzenesulfonamides according to the invention correspond to the following general formula (I): ##STR1## in which: V represents, for example, hydrogen,W represents, for example CF.sub.3,X represents, for example, hydrogen,Y represents, for example, hydrogen,n is 2 or 3,Z represents, for example, the group NR.sub.4, in which R.sub.4 represents, for example, hydrogen.These compounds are useful in pharmaceutical compositions for the treatment of nervous disorders with anxiety.
    Type: Grant
    Filed: July 26, 1985
    Date of Patent: October 3, 1989
    Assignee: DROPIC-Societe Civile de gestion de droits de Propriete Industrielle
    Inventors: Pierre Roger, Patrick Choay, Jean-Paul Fournier
  • Patent number: 4761430
    Abstract: The invention relates to new medicaments having lipid regulating properties nd processes for their preparation.The medicaments according to the invention contain as active principle at least one compound, (or its corresponding optical isomer) of the arylsulfonamide type corresponding to the formula: ##STR1## in which: Ar prepresents an aromatic ring which may if necessary be substituted;n+m+1 is comprised from 3 to 11, being preferably equal to 3, 5 or 10;R.sub.5 and R.sub.6 represent independently of one another, particularly an alkyl radical;R.sub.4 represents the hydroxy group, the radical OR.sub.7 in which R.sub.7 is particularly an alkyl group, the radical NR.sub.8 R.sub.9 in which R.sub.8 and R.sub.9 are identical or different, and represent in particular a hydrogen atom, and form with the nitrogen a nitrogenous heterocyclic ring with 5 or 6 links.
    Type: Grant
    Filed: September 23, 1986
    Date of Patent: August 2, 1988
    Assignee: Dropic, Societe civile de gestion de droits de propriete industrielle
    Inventors: Patrick Choay, Pierre Roger, Dominique Olliero
  • Patent number: 4760062
    Abstract: The invention relates to new N-cyclic benzenesulfonamides, their process of preparation and their use as active substance of pharmaceutical compositions. The new benzenesulfonamides according to the invention correspond to the following general formula (I): ##STR1## in which: V represents, for example, hydrogen,W represents, for example CF.sub.3,X represents, for example, hydrogen,Y represents, for example, hydrogen,n is 2 or 3,Z represents, for example, the group NR.sub.4, in which R.sub.4 represents, for example, hydrogen.These compounds are useful in pharmaceutical compositions for the treatment of nervous disorders with anxiety.
    Type: Grant
    Filed: October 18, 1984
    Date of Patent: July 26, 1988
    Assignee: DROPIC, Societe Civile de gestion de droits de Propriete Industrielle
    Inventors: Pierre Roger, Patrick Choay, Jean-Paul Fournier
  • Patent number: 4613618
    Abstract: The invention relates to new medicaments having lipid regulating properties and processes for their preparation.The medicaments according to the invention contain as active principle at least one compound, (or its corresponding optical isomer) of the arylsulfonamide type corresponding to the formula: ##STR1## in which: Ar represents an aromatic ring which may if necessary be substituted;n+m+1 is comprised from 3 to 11, being preferably equal to 3,5 or 10, or is comprised from 1 to 11 when Ar represents an aryl group in which at least one of the R.sub.1,R.sub.2 and R.sub.3 radicals is a CF.sub.3 group;R.sub.5 and R.sub.6 represent independently of one another particularly an alkyl radical;R.sub.4 represents the hydroxy group, the radical OR.sub.7 in which R.sub.7 is particularly an alkyl group, the radical NR.sub.8 R.sub.9 in which R.sub.8 and R.sub.9 are identical or different, and represent in particular a hydrogen atom, and form with the nitrogen a nitrogenous heterocyclic ring with 5 or 6 links.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: September 23, 1986
    Assignee: Choay S.A.
    Inventors: Patrick Choay, Pierre Roger, Dominique Olliero
  • Patent number: 4585769
    Abstract: The invention relates to new benzenesulfonyl-lactams, process for their preparation and their use as active substance in pharmaceutical compositions.Compounds according to the invention correspond to the general formula (I): ##STR1## in which: X can represent hydrogen,Y can represent the CF.sub.3 group,Z can represent chlorine,W can represent hydrogen,n is 1, 2 or 3,R.sub.1 can represent hydrogen,R.sub.2 can represent the OH group, provided that when n is 2 or 3, X or Z represents an alkoxy group from 1 to 4 carbon atoms or that Y represents the CF.sub.3 or NO.sub.2 group, and when n is 1, Y or W represents the CF.sub.3 group.These new compounds may be introduced as active substances, particularly in the treatment of disorders of the memory.
    Type: Grant
    Filed: October 18, 1984
    Date of Patent: April 29, 1986
    Assignee: DROPIC - Societe Civile de gestion de droits de propriete Industrielle CHOAY
    Inventors: Pierre Roger, Patrick Choay, Jean-Paul Fournier
  • Patent number: 4378366
    Abstract: This invention relates to trifluorethylamines and to a process for producing the same.These trifluorethylamines are substituted on the nitrogen atom with a lower alkyl or a cyclo lower alkyl radical.They are endowed with interesting pharmacological properties.
    Type: Grant
    Filed: August 24, 1981
    Date of Patent: March 29, 1983
    Assignee: Science Union et Cie
    Inventors: Charles Malen, Pierre Roger, Michel Laubie
  • Patent number: 4315019
    Abstract: This invention relates to novel substituted aryl lower alkamine and more precisely to arylmethylamine, the methyl group of which is substituted with one more polyfluoromethyl radicals.This invention also relates to the process for producing said compounds.The resulting compounds have pharmacological utility and may be used as a drug in human and veterinary medicine.
    Type: Grant
    Filed: August 18, 1980
    Date of Patent: February 9, 1982
    Assignee: Science Union et Cie
    Inventors: Charles Malen, Pierre Roger, Michel Laubie
  • Patent number: 4315020
    Abstract: Certain phenyl amines have been prepared wherein the "methyl" carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.
    Type: Grant
    Filed: October 15, 1980
    Date of Patent: February 9, 1982
    Assignee: Science Union et Cie
    Inventors: Charles E. Malen, Pierre Roger, Michel Laubie
  • Patent number: 4283407
    Abstract: This invention relates to omega-mercaptopropionylamides, the nitrogen atom of which is included as a ring atom of a cyclic amino acid.The application also discloses a process for producing said compounds which comprises reacting an omega-mercaptopropionic acid, or a functional derivative thereof, with a cyclic amino acid.This invention further relates to pharmaceutical compositions incorporating such an omega-mercaptopropionylamide as active ingredient together with a pharmaceutically-acceptable carrier or vehicle, and a method of employing said compounds.They find a use in human therapy, namely, as antihypertensive agents.
    Type: Grant
    Filed: September 25, 1978
    Date of Patent: August 11, 1981
    Assignee: Science Union et Cie
    Inventors: Charles Malen, Pierre Roger, Michel Laubie
  • Patent number: 4267345
    Abstract: Certain arylmethyl amines have been prepared wherein the "methyl" carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.
    Type: Grant
    Filed: April 19, 1979
    Date of Patent: May 12, 1981
    Assignee: Science Union et Cie
    Inventors: Charles E. Malen, Pierre Roger, Michel Laubie