Patents by Inventor Pierre Savi

Pierre Savi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biotinylated hexadecasaccharides, preparation and use thereof
    Patent number: 8703738
    Abstract: The invention concerns novel biotinylated hexadecasaccharides of general formula (I) wherein: Biot is a biotin derivative; R, R1 and R2, represent independently of one another a C1-C6 alkoxy or and —OSO3; R3 represents a C1-C6 alkoxy or an —OSO3, or R3 constitutes a —O—CH2— bridge; Pe represents a saccharide concatenation; as well as their pharmaceutically acceptable salts, and their use as medicines.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: April 22, 2014
    Assignee: SANOFI
    Inventors: Philippe Duchaussoy, Jean Pascal Herault, Jean Marc Herbert, Maurice Petitou, Pierre Savi
  • Biotinylated hexadecasaccharides, preparation and use thereof
    Patent number: 8557968
    Abstract: The invention concerns novel biotinylated hexadecasaccharides of general formula (I) wherein: Biot is a biotin derivative; R, R1 and R2, represent independently of one another a C1-C6 alkoxy or and —OSO3; R3 represents a C1-C6 alkoxy or an —OSO3, or R3 constitutes a —O—CH2— bridge; Pe represents a saccharide concatenation; as well as their pharmaceutically acceptable salts, and their use as medicines.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: October 15, 2013
    Assignee: Sanofi
    Inventors: Philippe Duchaussoy, Jean Pascal Herault, Jean Marc Herbert, Maurice Petitou, Pierre Savi
  • Pyridinopyridinone derivatives, preparation thereof and therapeutic use thereof
    Patent number: 8436011
    Abstract: The present invention relates to pyridopyridone derivatives of formula (I): in which the variables are as defined herein, to their preparation and to their therapeutic use as inhibitors of the kinase activity of PDGF (platelet-derived growth factor) ligand receptors and possibly of FLT3 (fms-like tyrosine kinase receptor) ligand receptors.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: May 7, 2013
    Assignee: Sanofi
    Inventors: Patrice Bellevergue, Gilbert Lassalle, Gary McCort, Valerie Martin, Pierre Savi, Cecile Volle-Challier
  • BIOTINYLATED HEXADECASACCHARIDES, PREPARATION AND USE THEREOF
    Publication number: 20130004551
    Abstract: The invention concerns novel biotinylated hexadecasaccharides of general formula (I) wherein: Biot is a biotin derivative; R, R1 and R2, represent independently of one another a C1-C6 alkoxy or and —OSO3; R3 represents a C1-C6 alkoxy or an —OSO3, or R3 constitutes a —O—CH2— bridge; Pe represents a saccharide concatenation; as well as their pharmaceutically acceptable salts, and their use as medicines.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 3, 2013
    Applicant: SANOFI
    Inventors: Philippe Duchaussoy, Jean Pascal Herault, Jean Marc Herbert, Maurice Petitou, Pierre Savi
  • Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative
    Patent number: 8318696
    Abstract: The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polysaccharides.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: November 27, 2012
    Assignee: Sanofi
    Inventors: Philippe Duchaussoy, Jean-Marc Herbert, Maurice Petitou, Pierre Savi
  • Novel Polysaccharides with Antithrombotic Activity Comprising at Least One Covalent Bond with Biotin or a Biotin Derivative
    Publication number: 20110144042
    Abstract: The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polysaccharides.
    Type: Application
    Filed: February 28, 2011
    Publication date: June 16, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Philippe Duchaussoy, Jean-Marc Herbert, Maurice Petitou, Pierre Savi
  • PYRIDINOPYRIDINONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20110124643
    Abstract: The present invention relates to pyridopyridone derivatives of formula (I): in which the variables are as defined herein, to their preparation and to their therapeutic use as inhibitors of the kinase activity of PDGF (platelet-derived growth factor) ligand receptors and possibly of FLT3 (fms-like tyrosine kinase receptor) ligand receptors.
    Type: Application
    Filed: January 6, 2011
    Publication date: May 26, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Patrice BELLEVERGUE, Gilbert LASSALLE, Gary MCCORT, Valerie MARTIN, Pierre SAVI, Cecile VOLLE-CHALLIER
  • Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative
    Patent number: 7943595
    Abstract: The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polysaccharides.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: May 17, 2011
    Assignee: sanofi-aventis
    Inventors: Philippe Duchaussoy, Jean Marc Herbert, Maurice Petitou, Pierre Savi
  • BIOTINYLATED HEXADECASACCHARIDES, PREPARATION AND USE THEREOF
    Publication number: 20100279960
    Abstract: The invention concerns novel biotinylated hexadecasaccharides of general formula (I) wherein: Biot is a biotin derivative; R, R1 and R2, represent independently of one another a C1-C6 alkoxy or and —OSO3; R3 represents a C1-C6 alkoxy or an —OSO3, or R3 constitutes a —O—CH2— bridge; Pe represents a saccharide concatenation; as well as their pharmaceutically acceptable salts, and their use as medicines.
    Type: Application
    Filed: July 16, 2010
    Publication date: November 4, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Philippe DUCHAUSSOY, Jean Pascal HERAULT, Jean Marc HERBERT, Maurice PETITOU, Pierre SAVI
  • BIOTINYLATED HEXADECASACCHARIDES, PREPARATION AND USE THEREOF
    Publication number: 20070270342
    Abstract: The invention concerns novel biotinylated hexadecasaccharides of general formula (I) wherein: Biot is a biotin derivative; R, R1 and R2, represent independently of one another a C1-C6 alkoxy or and —0S03; R3 represents a C1-C6 alkoxy or an —OSO3, or R3 constitutes a —O—CH2-bridge; Pe represents a saccharide concatenation; as well as their pharmaceutically acceptable salts, and their use as medicines.
    Type: Application
    Filed: March 9, 2007
    Publication date: November 22, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Philippe DUCHAUSSOY, Jean HERAULT, Jean HERBERT, Maurice PETITOU, Pierre SAVI
  • Novel polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative
    Publication number: 20060160768
    Abstract: The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polysaccharides.
    Type: Application
    Filed: January 14, 2005
    Publication date: July 20, 2006
    Inventors: Philippe Duchaussoy, Jean-Marc Herbert, Maurice Petitou, Pierre Savi
  • Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative
    Patent number: 6844329
    Abstract: The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polysaccharides.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: January 18, 2005
    Assignee: Sanofi-Synthelabo
    Inventors: Philippe Duchaussoy, Jean-Marc Herbert, Maurice Petitou, Pierre Savi
  • Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative
    Publication number: 20040024197
    Abstract: The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polysaccharides.
    Type: Application
    Filed: March 21, 2003
    Publication date: February 5, 2004
    Inventors: Phillppe Duchaussoy, Jean-Marc Herbert, Maurice Petitou, Pierre Savi
  • Associations of active principles containing clopidogrel and an antithrombotic agent
    Patent number: 5989578
    Abstract: The invention relates to a pharmaceutical composition containing an association of active principles, wherein the active principles are clopidogrel and aspirin, each constituent being present in a free form or in the form of a pharmaceutically acceptable salt.
    Type: Grant
    Filed: August 12, 1998
    Date of Patent: November 23, 1999
    Assignee: Sanofi
    Inventors: Andre Bernat, Jean Marc Herbert, Pierre Savi
  • Method for the secondary prevention of ischemic events
    Patent number: 5576328
    Abstract: The invention relates to a new method for the secondary prevention of ischemic events comprising administering to a man in need thereof a therapeutically effective amount of a compound selected from clopidogrel and its pharmaceutically acceptable acid addition salts in association with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: January 31, 1994
    Date of Patent: November 19, 1996
    Assignee: Elf Sanofi
    Inventors: Jean-Marc Herbert, Daniel Frehel, Andr e Bernat, Alain Badorc, Pierre Savi, Denis Delebass ee, Gilles Kieffer, Ghislain Defreyn, Jean-Pierre Maffrand