Patents by Inventor Pierre Schaaf
Pierre Schaaf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11879038Abstract: The present invention relates to a polymer foam, said polymer foam comprising pores forming an open-cell polymer foam, said polymer foam comprising a supramolecular gel inside pores, and said polymer foam comprising at least one enzyme. The present invention relates to a supramolecular gel; its preparation and its applications, notably in chemical synthesis and kinetic resolution, in particular of organic compounds. The present invention also relates to flow chemistry.Type: GrantFiled: September 9, 2020Date of Patent: January 23, 2024Assignees: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALEInventors: Loïc Jierry, Christophe Serra, Pierre Schaaf, Jennifer Rodon Fores, Fouzia Boulmedais
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Patent number: 11602578Abstract: The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.Type: GrantFiled: November 2, 2018Date of Patent: March 14, 2023Assignees: Université de Strasbourg, Institut National De La Sante Et De La Recherche Medicale (INSERM), Protip MedicalInventors: Philippe Lavalle, Pierre Schaaf, Nihal Engin Vrana, Angela Mutschler, Cynthia Calligaro, Lorène Tallet
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Publication number: 20220389083Abstract: The present invention relates to a process of preparation of a biomaterial comprising the steps of: a) Preparing a solution comprising at least one protein having a solubility in water superior or equal to about 10 mg/mL and at least one salt having solubility in water superior or equal to about 500 mg/mL, b) Evaporating the solution obtained in step a) as is, as a foam obtained by foaming the solution obtained in step a), or as a mixture thereof, at a temperature comprised of from 4 to 50° C. in atmospheric pressure or at lower temperatures under vacuum or at a pressure lower than atmospheric pressure, until the formation of two non-miscible phases or until obtaining a substantially dry solid, thereby obtaining a biomaterial. The present invention also relates to a biomaterial obtainable by the process, and to the use of the biomaterial as a support for in vitro tissue engineering and/or for in vitro cell culture and in vitro expansion and/or as an implantable medical device, or as a drug.Type: ApplicationFiled: October 23, 2020Publication date: December 8, 2022Inventors: Eya ALOUI, Marcella DE GIORGI, Benoît FRISCH, Philippe LAVALLE, Pierre SCHAAF
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Patent number: 11471558Abstract: The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.Type: GrantFiled: May 2, 2017Date of Patent: October 18, 2022Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ DE STRASBOURG, PROTIP MEDICALInventors: Philippe Lavalle, Pierre Schaaf, Nihal Engin Vrana, Angela Mutschler
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Publication number: 20220315710Abstract: The present invention relates to a polymer foam, said polymer foam comprising pores forming an open-cell polymer foam, said polymer foam comprising a supramolecular gel inside pores, and said polymer foam comprising at least one enzyme. The present invention relates to a supramolecular gel; its preparation and its applications, notably in chemical synthesis and kinetic resolution, in particular of organic compounds. The present invention also relates to flow chemistry.Type: ApplicationFiled: September 9, 2020Publication date: October 6, 2022Inventors: Loïc JIERRY, Christophe SERRA, Pierre SCHAAF, Jennifer RODON FORES, Fouzia BOULMEDAIS
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Publication number: 20210010050Abstract: Disclosed is a liquid composition including a protein, a polyphenol and a morphogen; to a solid composition including the cross-linked product of a protein and a polyphenol; to a biosensor and a biofuel cell including the solid composition bound to a surface of an electrochemical probe; to a process for the detection of an analyte with the biosensor; and to the use of a ferrocene as a morphogen in an electrodeposition process.Type: ApplicationFiled: March 22, 2019Publication date: January 14, 2021Inventors: Fouzia BOULMEDAIS, Pierre SCHAAF, Loïc JIERRY, Janwa EL MAISS, Paolo LUPATTELLI, Marco CUCCARESE
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Patent number: 10864296Abstract: A polyelectrolyte coating comprises at least one polycationic layer consisting of at least one polyarginine as herein defined and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit. Also disclosed is a method of preventing a bacterial infection in an individual.Type: GrantFiled: July 11, 2017Date of Patent: December 15, 2020Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ DE STRASBOURG, PROTIP MEDICALInventors: Philippe Lavalle, Pierre Schaaf, Nihal Engin Vrana, Angela Mutschler
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Publication number: 20200289706Abstract: The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.Type: ApplicationFiled: November 2, 2018Publication date: September 17, 2020Inventors: Philippe LAVALLE, Pierre SCHAAF, Nihal Engin VRANA, Angela MUTSCHLER, Cynthia CALLIGARO, Lorène TALLET
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Publication number: 20190375791Abstract: The present invention relates to a cateslytin peptide having an amino acid sequence consisting or consisting essentially of the sequence of SEQ ID NO: 1, wherein at least 80%, preferably at least 90%, of the amino acids residues of said cateslytin are D-configured. The invention also relates to the use of said cateslytin peptide as a drug, especially in the treatment of an infection in a patient in needs thereof.Type: ApplicationFiled: November 22, 2017Publication date: December 12, 2019Inventors: Céline MARBAN, Marie-Hélène METZ-BOUTIGUE, Philippe LAVALLE, Pierre SCHAAF, Youssef HAIKEL
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Publication number: 20190117832Abstract: The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.Type: ApplicationFiled: May 2, 2017Publication date: April 25, 2019Inventors: Philippe LAVALLE, Pierre SCHAAF, Nihal Engin VRANA, Angela MUTSCHLER
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Publication number: 20180353333Abstract: The present invention relates to a nanofilm including at least one polycation and one polysulfated oligosaccharide. The present invention also relates to the nanofilms obtainable by simultaneously or alternately sputtering at least one polycation solution and at least one polysulfated oligosaccharide solution and to the use of said nanofilms on skin, skin conditions, wounds, or mucous membranes. The present invention also relates to a nanofilm for the use thereof in a method for releasing polysulfated oligosaccharide upon contact with exuding wounds.Type: ApplicationFiled: December 2, 2016Publication date: December 13, 2018Applicants: Urgo Recherche Innovation et Developpement, Centre National de la Recherche Scientifique -CNRS -Inventors: Fouzia Boulmedais, Pierre Schaaf, Jean-Marc Pernot, Christelle Laurensou
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Publication number: 20180318472Abstract: A polyelectrolyte coating comprises at least one polycationic layer consisting of at least one polyarginine as herein defined and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit. Also disclosed is a method of preventing a bacterial infection in an individual.Type: ApplicationFiled: July 11, 2017Publication date: November 8, 2018Inventors: Philippe LAVALLE, Pierre SCHAAF, Nihal Engin VRANA, Angela MUTSCHLER
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Patent number: 9005694Abstract: The invention relates to a method for providing organic, semi-organic, mineral, inorganic and hybrid thin layers and thin layers containing nanoparticles, by simultaneous or alternate spraying of solutions of reactive partners (that is polymer/polymer interacting by hydrogen bonding, polyelectrolyte/small oligo-ion, inorganic compounds, etc.) on the surface of a solid substrate.Type: GrantFiled: May 20, 2011Date of Patent: April 14, 2015Assignees: Centre National de la Recherche Scientifique (CNRS), Universite de StrasbourgInventors: Gabriela Popa, Gero Decher, Fouzia Boulmedais, Olivier Felix, Pierre Schaaf, Jean-Claude Voegel, Joseph Hemmerle, Peng Zhao
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Publication number: 20140328883Abstract: The invention relates to methods for preparing crosslinked polyelectrolytes, in particular crosslinked polyelectrolytes multilayer films. The invention also relates to a method of coating a surface, and the obtained coated article.Type: ApplicationFiled: December 30, 2013Publication date: November 6, 2014Inventors: Catherine Picart, Jean-Claude Voegel, Benoit Frisch, Pierre Schaaf, Gero Decher, Frederic Cuisinier
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Publication number: 20130129907Abstract: The invention relates to a method for providing organic, semi-organic, mineral, inorganic and hybrid thin layers and thin layers containing nanoparticles, by simultaneous or alternate spraying of solutions of reactive partners (that is polymer/polymer interacting by hydrogen bonding, polyelectrolyte/small oligo-ion, inorganic compounds, etc.) on the surface of a solid substrate.Type: ApplicationFiled: May 20, 2011Publication date: May 23, 2013Applicants: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Gabriela Popa, Gero Decher, Fouzia Boulmedais, Olivier Felix, Pierre Schaaf, Jean-Claude Voegel, Joseph Hemmerle, Peng Zhao
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Publication number: 20110151564Abstract: The invention relates to the use of a unit including a substrate and polyelectrolyte multilayer films deposited thereon in order to: carry out a method involving the proliferation of initial stem or differentiated cells that are brought into contact with the unit; and cover the unit with confluent viable adherent cells resulting from the proliferation of the initial cells, the cover being obtained at the end of a period of no more than one month, such as 14 days, 11 days or, in particular, 7 days, after the initial cells are brought into contact with the unit.Type: ApplicationFiled: June 16, 2008Publication date: June 23, 2011Applicants: UNIVERSITE HENRI POINCARE NANCY 1, CHU DE NANCY-BRABOISInventors: Patrick Menu, Cedric Boura, Halima-Assia Kerdjoudj, Vanessa Moby, Nicolas Berthelemy, Jean-Claude Voegel, Pierre Schaaf, Jean-Francois Stoltz
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Publication number: 20100143434Abstract: The invention concerns a mechanically responsive supported polyelectrolyte multilayer film, comprising:—an elastic substrate, on which are alternately coated:—at least one exponentially growing film; and—at least one mechanically responsive barrier film. It further concerns a process for its preparation and the use of such films notably for mechanically responsive mixing or delivery of active substances. It further concerns dosage forms of a drug, biosensors and implants comprising such films.Type: ApplicationFiled: January 31, 2008Publication date: June 10, 2010Inventors: Pierre Schaaf, Jean-Claude Voegel
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Publication number: 20080171070Abstract: The invention relates to polyelectrolyte multilayer films presenting a tunable biological activity and methods for preparing the same. The invention further relates to surfaces presenting such films and uses thereof, such as for the controlled delivery of biologically active agents.Type: ApplicationFiled: January 31, 2006Publication date: July 17, 2008Inventors: Pierre Schaaf, Nadia Jessel, Joelle Ogier-Dirrig, Philippe Lavalle, Jean-Claude Voegel, Bernard Senger
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Publication number: 20070129792Abstract: The invention relates to methods for preparing crosslinked polyelectrolytes, in particular crosslinked polyelectrolytes multilayer films. The invention also relates to a method of coating a surface, and the obtained coated article.Type: ApplicationFiled: November 29, 2004Publication date: June 7, 2007Inventors: Catherine Picart, Jean-Claude Voegel, Benoit Frisch, Pierre Schaaf, Gero Decher, Frederic Cuisinier