Patents by Inventor Pierre Sinay

Pierre Sinay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060270627
    Abstract: A pharmaceutical composition including a therapeutically effective amount of at least one oligomannoside produced by chemical synthesis which is homologous to a wall oligomannoside of an infectious organism or pathogen, or a derivative thereof, and a pharmaceutically acceptable vehicle.
    Type: Application
    Filed: August 1, 2006
    Publication date: November 30, 2006
    Applicant: Centre Hospitalier regional universitaire (CHRU)
    Inventors: Jacques Esnault, Pierre Sinay, Reynald Chevalier, Jean-Frederic Colombel, Jean-Maurice Mallet, Boualem Sendid, Thierry Jouault, Daniel Poulain, Pierre-Andre Trinel
  • Patent number: 7109182
    Abstract: A pharmaceutical composition including a therapeutically effective amount of at least one oligomannoside produced by chemical synthesis which is homologous to a wall oligomannoside of an infectious organism or pathogen, or a derivative thereof, and a pharmaceutically acceptable vehicle.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: September 19, 2006
    Assignee: Centre Hospitalier Regional Universitaire (CHRU)
    Inventors: Jacques Esnault, Pierre Sinay, Reynald Chevalier, Jean-Frédéric Colombel, Jean-Maurice Mallet, Boualem Sendid, Thierry Jouault, Daniel Poulain, Pierre-André Trinel
  • Publication number: 20030105060
    Abstract: A pharmaceutical composition including a therapeutically effective amount of at least one oligomannoside produced by chemical synthesis which is homologous to a wall oligomannoside of an infectious organism or pathogen, or a derivative thereof, and a pharmaceutically acceptable vehicle.
    Type: Application
    Filed: May 23, 2002
    Publication date: June 5, 2003
    Applicant: Centre Hospitalier Regional Universitaire (CHRU)
    Inventors: Jacques Esnault, Pierre Sinay, Reynald Chevalier, Jean-Frederic Colombel, Jean-Maurice Mallet, Boualem Sendid, Thierry Jouault, Daniel Poulain, Pierre-Andre Trinel
  • Patent number: 4987223
    Abstract: The invention relates to derivatives with a uronic acid structure having substituents selected among a reactive group, a functionalisable group and --OH functions blocked by protective groups. These derivatives are useful for preparing glycosides, particularly enzyme substrates.
    Type: Grant
    Filed: October 27, 1982
    Date of Patent: January 22, 1991
    Assignee: Choay S.A.
    Inventors: Jean Choay, Jean-Claude Jacquinet, Maurice Petitou, Pierre Sinay
  • Patent number: 4943630
    Abstract: Novel processes for synthesizing acid mucopolysaccharide fragments having from 2-12 saccharides and substantially pure products of a single structure produced thereby. Condensation are disclosed between a first protected saccharide and a second protected saccharide to form a protected condensation product having units linked in the manner found in chondroitin sulfate and dermatan sulfate and having protecting groups thereon which allow selective positioning of functional groups, in particular sulfate, at desired positions. Other condensations are disclosed in which a protected condensation product is formed which can be elongated, and has protecting groups thereon which allow selective positioning of functional groups, in particular sulfate, at desired positions. Also disclosed is a process for selectively positioning functional groups on a protected acid mucopolysaccharide having from 2-12 units.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: July 24, 1990
    Assignee: Choay, S.A.
    Inventors: Jean-Claude Jacquinet, Maurice Petitou, Pierre Sinay, Jean Choay
  • Patent number: 4818816
    Abstract: The invention relates to a process for the organic synthesis of oligosaccharides constituting or comprising fragments of acid mucopolysaccharides comprising the reaction of two compounds constituted or terminated by units of glucosamine structure and of uronic acid structure respectively, said units being specifically substituted. This process particularly enables valuable anticoagulant drugs to be obtained.
    Type: Grant
    Filed: October 26, 1987
    Date of Patent: April 4, 1989
    Assignee: Choay, S.A.
    Inventors: Maurice Petitou, Jean-Claude Jacquinet, Pierre Sinay, Jean Choay, Jean-Claude Lormeau, Mahmoud Nassr
  • Patent number: 4801583
    Abstract: The oligosaccharides of the invention contain or are constituted by a tetrasaccharide enchainment of the formula: ##STR1## in which R.sub.1 represents an organic anion, R.sub.2 is identical to R.sub.1 or represents a hydrogen atom, N.sub.1 and N.sub.2 represent a functional amino group.
    Type: Grant
    Filed: May 15, 1985
    Date of Patent: January 31, 1989
    Assignee: Choay S.A.
    Inventors: Maurice Petitou, Jean-Claude Lormeau, Jean Choay, Jean-Claude Jacquinet, Pierre Sinay
  • Patent number: 4774231
    Abstract: 1,4.alpha.disaccharides of formula: ##STR1## with Z representing a nitrogenous functional group,M hydrogen or a sulphate or acetyl group,R an alkyl radical of 1 to 4 carbon atoms andA functional group such as an acid group, or a derivative.
    Type: Grant
    Filed: July 21, 1986
    Date of Patent: September 27, 1988
    Assignee: Choay S.A.
    Inventors: Maurice Petitou, Pierre Sinay, Jean Choay, Jean-Claude Lormeau
  • Patent number: 4607025
    Abstract: 1,4 .alpha. disaccharides of formula: ##STR1## with Z representing a nitrogenous functional group,M hydrogen or a sulphate or acetyl group,R an alkyl radical of 1 to 4 carbon atoms andA a functional group such as an acid group, or a derivative.
    Type: Grant
    Filed: December 20, 1982
    Date of Patent: August 19, 1986
    Assignee: Choay S.A.
    Inventors: Maurice Petitou, Pierre Sinay, Jean Choay, Jean-Claude Lormeau
  • Patent number: 4370265
    Abstract: Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens, comprising an acyl-muramic acid group, wherein acyl means acetyl or glycolyl, and a short peptide chain linked to said acyl-muramic acid group, the first and second amino acids of said peptide chain being preferentially alanine and glutamic acid respectively.
    Type: Grant
    Filed: May 15, 1978
    Date of Patent: January 25, 1983
    Assignee: Agence Nationale de Valorisation
    Inventors: Arlette Adam, Francoise Audibert, Louis Chedid, Jean Choay, Rita Ciorbaru, Fabrielle Ellouz, Dominique Juy, Pierre Lefrancier, Claude Merser, Jean-Francois Petit, Pierre Sinay, Edgar Lederer
  • Patent number: 4235771
    Abstract: Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens, comprising an acyl-muramic acid group, wherein acyl means acetyl or glycolyl, and a short peptide chain linked to said acyl-muramic acid group, the first and second amino acids of said peptide chain being preferentially alanine and glutamic acid respectively.
    Type: Grant
    Filed: May 15, 1978
    Date of Patent: November 25, 1980
    Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR)
    Inventors: Arlette Adam, Francoise Audibert, Louis Chedid, Jean Choay, Rita Ciorbaru, Fabrielle Ellouz, Dominique Juy, Pierre Lefrancier, Claude Merser, Jean-Francois Petit, Pierre Sinay, Edgar Lederer
  • Patent number: 4186194
    Abstract: Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens, comprising an acyl-muramic acid group, wherein acyl means acetyl or glycolyl, and a short peptide chain linked to said acyl-muramic acid group, the first and second amino acids of said peptide chain being preferentially alanine and glutamic acid respectively.
    Type: Grant
    Filed: October 22, 1974
    Date of Patent: January 29, 1980
    Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR)
    Inventors: Arlette Adam, Francoise Audibert, Louis Chedid, Jean Choay, Rita Ciorbaru, Fabrielle Ellouz, Dominique Juy, Pierre Lefrancier, Claude Merser, Jean-Francois Petit, Pierre Sinay, Edgar Lederer