Patents by Inventor Pierre-Yves Dietrich

Pierre-Yves Dietrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell penetrating peptides
    Patent number: 9657064
    Abstract: The present invention relates to a short cell penetrating peptide derived from the Epstein-Barr virus basic leucine zipper transcriptional activator (ZEBRA), optionally linked to a cargo molecule. It also relates to a complex comprising the cell penetrating peptide and a cargo molecule, as well as cells loaded with the complex and the use thereof in therapy and diagnosis.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: May 23, 2017
    Assignees: LES HOPITAUX UNIVERSITAIRES DE GENEVE, UNIVERSITE DE GENEVE
    Inventors: Madiha Derouazi, Paul Walker, Pierre-Yves Dietrich
  • MULTI-EPITOPIC VACCINE
    Publication number: 20160031946
    Abstract: The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope; and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.
    Type: Application
    Filed: October 15, 2015
    Publication date: February 4, 2016
    Inventors: MADIHA SABIHA DEROUAZI, PAUL R. WALKER, PIERRE-YVES DIETRICH
  • Multi-epitopic vaccine
    Patent number: 9187534
    Abstract: The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope; and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: November 17, 2015
    Assignees: UNIVERSITE DE GENEVE, HOPITAUX UNIVERSITAIRES DE GENEVE
    Inventors: Madiha Sabiha Derouazi, Paul R. Walker, Pierre-Yves Dietrich
  • Cell Penetrating Peptides
    Publication number: 20150239938
    Abstract: The present invention relates to a short cell penetrating peptide derived from ZEBRA, optionally linked to a cargo molecule. It also relates to a complex comprising said cell penetrating peptide and a cargo molecule, as well as cells loaded with said complex and the use thereof in therapy and diagnosis.
    Type: Application
    Filed: September 12, 2013
    Publication date: August 27, 2015
    Applicants: LES HOPITAUX UNIVERSITAIRES DE GENEVE, UNIVERSITE DE GENEVE
    Inventors: Madiha Derouazi, Paul Walker, Pierre-Yves Dietrich
  • MULTI-EPITOPIC VACCINE
    Publication number: 20120231030
    Abstract: The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope; and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.
    Type: Application
    Filed: March 9, 2012
    Publication date: September 13, 2012
    Applicants: HOPITAUX UNIVERSITAIRES DE GENEVE, UNIVERSITE DE GENEVE
    Inventors: MADIHA SABIHA DEROUAZI, Paul R. Walker, Pierre-Yves Dietrich
  • Junctional adhesion molecule-C (JAM-C) binding compounds and methods of their use
    Patent number: 8007797
    Abstract: The present invention relates to the use of a compound that specifically binds to JAM-C or JAM-B for the treatment of gliomas. More specifically the invention relates to the use of an antagonist of JAM-B or JAM-C for the treatment of glioma, in particular astrocytoma.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: August 30, 2011
    Assignee: Merck Serono S.A.
    Inventors: Pierre-Yves Dietrich, Mirna Tenan, Michel Aurrand-Lions, Beat Albert Imhof
  • JUNCTIONAL ADHESION MOLECULE-C (JAM-C) BINDING COMPOUNDS AND METHODS OF THEIR USE
    Publication number: 20100034737
    Abstract: The present invention relates to the use of a compound that specifically binds to JAM-C or JAM-B for the treatment of gliomas. More specifically the invention relates to the use of an antagonist of JAM-B or JAM-C for the treatment of glioma, in particular astrocytoma.
    Type: Application
    Filed: September 28, 2007
    Publication date: February 11, 2010
    Inventors: Pierre-Yves Dietrich, Mirna Tenan, Michel Aurrand-lions, Beat Albert Imhof