Patents by Inventor Pieter C. J. M. Res

Pieter C. J. M. Res has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene constructs coding for CD40-binding activating antibodies
    Patent number: 7820807
    Abstract: Disclosed are agonist anti-CD40 molecules, including monoclonal antibodies, which can bind to and stimulate professional and non-professional human antigen-presenting cells (“APCs”), enhance the stimulatory effect of CD40L on CD40 positive cells and/or induce phenotypical maturation of monocyte derived dendritic cells. Several such monoclonal antibodies are provided, and cell lines producing them have been deposited at the American Type Culture Collection.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: October 26, 2010
    Assignee: Pangenetics BV
    Inventors: David Thomas, Mark De Boer, Pieter C. J. M. Res, Peter J. Simons
  • CD40-BINDING ACTIVATING ANTIBODIES
    Publication number: 20090311268
    Abstract: Disclosed are agonist anti-CD40 molecules, including monoclonal antibodies, which can bind to and stimulate professional and non-professional human antigen-presenting cells (“APCs”), enhance the stimulatory effect of CD40L on CD40 positive cells and/or induce phenotypical maturation of monocyte derived dendritic cells. Several such monoclonal antibodies are provided, and cell lines producing them have been deposited at the American Type Culture Collection.
    Type: Application
    Filed: April 8, 2009
    Publication date: December 17, 2009
    Applicant: Pangenetics BV
    Inventors: David Thomas, Mark de Boer, Pieter C.J.M. Res, Peter J. Simons
  • CD40-binding activating antibodies
    Patent number: 7547438
    Abstract: Disclosed are agonist anti-CD40 molecules, including monoclonal antibodies, which can bind to and stimulate professional and non-professional human antigen-presenting cells (“APCs”), enhance the stimulatory effect of CD40L on CD40 positive cells and/or induce phenotypical maturation of monocyte derived dendritic cells. Several such monoclonal antibodies are provided, and cell lines producing them have been deposited at the American Type Culture Collection.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: June 16, 2009
    Assignee: Pangenetics BV
    Inventors: David Thomas, Mark De Boer, Pieter C. J. M. Res, Peter J. Simone
  • Induction of cytotoxic T lymphocyte responses using anti-CD40 antibodies
    Patent number: 7172759
    Abstract: Disclosed are methods of inducing maturation of antigen presenting cells and cytotoxic T lymphocyte responses utilizing agonist anti-CD40 antibodies that do not block the binding of CD40L to CD40.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: February 6, 2007
    Assignee: Pangenetics BV
    Inventors: David Thomas, Mark de Boer, Pieter C. J. M. Res, Peter J. Simons
  • CD40-binding APC-activating molecules
    Publication number: 20010026932
    Abstract: Disclosed are agonist anti-CD40 molecules, including monoclonal antibodies, which can bind to and stimulate professional and non-professional human antigen-presenting cells (“APCs”), enhance the stimulatory effect of CD40L on CD40 positive cells and/or induce phenotypical maturation of monocyte derived dendritic cells. Several such monoclonal antibodies are provided, and cell lines producing them have been deposited at the American Type Culture Collection.
    Type: Application
    Filed: February 1, 2001
    Publication date: October 4, 2001
    Inventors: David Thomas, Mark De Boer, Pieter C.J.M. Res, Peter J. Simons