Abstract: A hinge structure for pivotally mounting a first telecommunications element to a second telecommunications element includes a hinge pin provided on the first element and a hinge pin receiver provided on the second element. The hinge pin defines a notch separating the pin into two pin halves. The hinge pin receiver defines two sets of opposing surfaces, the two sets separated by a divider, the divider configured to be accommodated by the notch when the hinge pin is inserted into the hinge pin receiver, wherein each opposing surface set defines a slot for receiving each pin half.

Abstract: The invention relates to chimeric GPCRs having extracellular loops from a first GPCR and intracellular loops from a second GPCR, and to screening methods for identifying compounds or ligands that bind to an active conformation of a GPCR in which such chimeric GPCRs are used.