Patents by Inventor Pieter De Bleser

Pieter De Bleser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liver-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
    Publication number: 20230293728
    Abstract: Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
    Type: Application
    Filed: April 14, 2023
    Publication date: September 21, 2023
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • Liver-specific nucleic acid regulatory elements and methods and use thereof
    Patent number: 11654201
    Abstract: Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: May 23, 2023
    Assignees: VIB VZW, Universiteit Gent, Life Sciences Research Partners VZW
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • Muscle-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
    Publication number: 20210395770
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.
    Type: Application
    Filed: June 9, 2021
    Publication date: December 23, 2021
    Inventors: Thierry Vandendriessche, Marinee Chuah, Pieter De Bleser
  • Muscle-specific nucleic acid regulatory elements and methods and use thereof
    Patent number: 11072801
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: July 27, 2021
    Assignees: VRIJE Universiteit Brussel, VIB VZW, Universiteit Gent
    Inventors: Thierry Vandendriessche, Marinee Chuah, Pieter De Bleser
  • Muscle-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
    Publication number: 20200407746
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.
    Type: Application
    Filed: July 9, 2020
    Publication date: December 31, 2020
    Inventors: Thierry Vandendriessche, Marinee Chuah, Pieter De Bleser
  • Muscle-specific nucleic acid regulatory elements and methods and use thereof
    Patent number: 10731177
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: August 4, 2020
    Assignees: Vrije Universiteit Brussel, VIB VZW, Universiteit Gent
    Inventors: Thierry Vandendriessche, Marinee Chuah, Pieter De Bleser
  • LIVER-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF
    Publication number: 20200038522
    Abstract: Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
    Type: Application
    Filed: October 21, 2019
    Publication date: February 6, 2020
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • Liver-specific nucleic acid regulatory elements and methods and use thereof
    Patent number: 10471157
    Abstract: Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: November 12, 2019
    Assignees: VIB VZW, Universiteit Gent
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • LIVER-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF
    Publication number: 20190046663
    Abstract: Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
    Type: Application
    Filed: October 30, 2018
    Publication date: February 14, 2019
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • Liver-specific nucleic acid regulatory elements and methods and use thereof
    Patent number: 10149914
    Abstract: Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: December 11, 2018
    Assignees: VIB VZW, Life Sciences Research Partners VZW, Universiteit Gent
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • Muscle-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
    Publication number: 20170275649
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.
    Type: Application
    Filed: March 27, 2017
    Publication date: September 28, 2017
    Inventors: Thierry Vandendriessche, Marinee Chuah, Pieter De Bleser
  • LIVER-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF
    Publication number: 20170209600
    Abstract: Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
    Type: Application
    Filed: April 10, 2017
    Publication date: July 27, 2017
    Applicants: VIB VZW, Life Sciences Research Partners VZW, Universiteit Gent
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • Liver-specific nucleic acid regulatory elements and methods and use thereof
    Patent number: 9617548
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: April 11, 2017
    Assignees: VIB VZW, Life Sciences Research Partners VZW, Universiteit Gent
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser
  • Muscle-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
    Publication number: 20160340693
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.
    Type: Application
    Filed: January 21, 2015
    Publication date: November 24, 2016
    Inventors: Thierry Vandendriessche, Marinee Chuah, Pieter De Bleser
  • Cardiac-specific nucleic acid regulatory elements and methods and use thereof
    Patent number: 9353164
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance cardiac-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: May 31, 2016
    Assignees: VIB VZW, Life Sciences Research Partners VZW, Universiteit Gent
    Inventors: Lay Khim Chuah, Thierry Vandendriessche, Pieter De Bleser
  • CARDIAC-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF
    Publication number: 20120252882
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance cardiac-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy.
    Type: Application
    Filed: October 29, 2010
    Publication date: October 4, 2012
    Inventors: Lay Khim Chuah, Thierry Vandendriessche, Pieter De Bleser
  • LIVER-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF
    Publication number: 20110184049
    Abstract: The present invention relates to nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy.
    Type: Application
    Filed: April 21, 2009
    Publication date: July 28, 2011
    Applicants: VIB VZW, Life Sciences Research Partners VZW, Universiteit Gent
    Inventors: Marinee Chuah, Thierry Vandendriessche, Pieter De Bleser