Abstract: A method of enhancing the nuclear spin polarization of target molecules (10) uses a hyperpolarized source material (12) that is co-confined with the target molecules (10) in a porous molecular matrix (20). The matrix (20) may be a D4R-polysiloxane copolymer such as polyoligosiloxysilicone number two (PSS-2) that has recesses of an appropriate diameter. A source material (12), such as parahydrogen, is transferred to the matrix (20) together with the target molecules (10), and an external pressure is applied to force them into the recesses of the matrix (20). The nano-confinement of the source material (12) and target molecules (10) together enables or enhances a transfer of spin polarization from the source material (12) to the target molecules (10). When the target molecules (10) are removed from the matrix (20), the enhanced spin polarization greatly enhances the signal strength of the target molecules (10) in any subsequent magnetic resonance measurement.

Abstract: A method of enhancing the nuclear spin polarization of target molecules (10) uses a hyperpolarized source material (12) that is co-confined with the target molecules (10) in a porous molecular matrix (20). The matrix (20) may be a D4R-polysiloxane copolymer such as polyoligosiloxysilicone number two (PSS-2) that has recesses of an appropriate diameter. A source material (12), such as parahydrogen, is transferred to the matrix (20) together with the target molecules (10), and an external pressure is applied to force them into the recesses of the matrix (20). The nano-confinement of the source material (12) and target molecules (10) together enables or enhances a transfer of spin polarization from the source material (12) to the target molecules (10). When the target molecules (10) are removed from the matrix (20), the enhanced spin polarization greatly enhances the signal strength of the target molecules (10) in any subsequent magnetic resonance measurement.

Abstract: The present invention relates to a new synthesis procedure for a family of silica based polymer materials synthesized through the interconnection of silicate oligomers with reactive silanes. By using this synthesis it is possible to generate novel silica based polymer materials. The present invention thus also relates to the members of this group of ordered silica based polymer materials whereby silicate oligomers are interconnected trough siloxane bridges and with empirical formulae Abx, whereby A presents the silicate oligomer, b the siloxane bridge and x the ratio between the number of silanes and the number of silicate oligomers in the material. This group of materials are particularly useful for certain applications.