Abstract: The invention relates to an applicator device comprising an applicator tip and a container part, wherein the container part comprises: (i) a container comprising a container wall, a valve, and a plunger, wherein the container wall, the valve, and the plunger together define a storage volume for containing a liquid, wherein the plunger comprises a circumferential wall, sealingly contacting the container wall; and (ii) a plunger advance system functionally coupled to the plunger and configured to advance the plunger for reducing the storage volume for expelling at least part of the liquid via said valve to said tip, wherein the plunger advance system is arranged outside the storage volume; wherein (a) the valve comprises a first spring system comprising a first spring material comprising a stainless steel material comprising a molybdenum content selected in the range of 0.5-7 wt.

Abstract: An applicator (1) for topical application of an acidic liquid (30) includes a container (3) containing the acidic liquid. The container has an opening (31) in fluid contact with a nib (2) for a controlled release of the acidic liquid, wherein the nib includes a plurality of fibers (20) and an adhesive material (21) adhering the fibers. A kit of parts (100) for topical application of an acidic liquid is also provided and includes (a) a liquid release unit (40) provided with a nib for a controlled release of the acidic liquid, and (b) a container unit (50) which includes a container configured to contain the acidic liquid. The container unit further includes a liquid release element for application of the acidic liquid to the nib, wherein the nib has a plurality of fibers and an adhesive material adhering the fibers.

Abstract: The invention provides a dermatological composition comprising materials of algae origin (e.g. Arthrospira platensis) and olive leaf origin, the composition at least comprising a polypeptide and hydroxytyrosol. The composition is for use in the treatment and/or prevention of a dermatological microbial infection, e.g. nail fungus, Athlete's foot, wound, chickenpox, acne. The invention also provides an applicator device comprising such composition. Further, the invention provides a method for preparing such dermatological composition. Especially, the composition at least comprises a polypeptide and hydroxytyrosol.

Abstract: The invention relates to an applicator device comprising an applicator tip and a container part, wherein the container part comprises: (i) a container comprising a container wall, a valve, and a plunger, wherein the container wall, the valve, and the plunger together define a storage volume for containing a liquid, wherein the plunger comprises a circumferential wall, sealingly contacting the container wall; and (ii) a plunger advance system functionally coupled to the plunger and configured to advance the plunger for reducing the storage volume for expelling at least part of the liquid via said valve to said tip, wherein the plunger advance system is arranged outside the storage volume; wherein (a) the valve comprises a first spring system comprising a first spring material comprising a stainless steel material comprising a molybdenum content selected in the range of 0.5-7 wt.

Abstract: Applicator (1) for topical application of an acidic liquid (30), the applicator comprising a container (3) containing said acidic liquid, the container comprising an opening (31) in fluid contact with a nib (2) for a controlled release of the acidic liquid, wherein the nib comprises a plurality of fibers (20) and an adhesive material (21) adhering the fibers. A kit of parts (100) for topical application of an acidic liquid, the kit of parts comprising (a) a liquid release unit (40) comprising a nib for a controlled release of the acidic liquid, and (b) a container unit (50) comprising a container configured to contain the acidic liquid, wherein the container unit further comprises a liquid release element for application of the acidic liquid to the nib, wherein the nib comprises a plurality of fibers and an adhesive material adhering the fibers.

Abstract: The invention provides a dermatological composition comprising materials of algae origin (e.g. Arthrospira platensis) and olive leaf origin, the composition at least comprising a polypeptide and hydroxytyrosol. The composition is for use in the treatment and/or prevention of a dermatological microbial infection, e.g. nail fungus, Athlete's foot, wound, chickenpox, acne. The invention also provides an applicator device comprising such composition. Further, the invention provides a method for preparing such dermatological composition. Especially, the composition at least comprises a polypetide and hydroxytyrosol.