Patents by Inventor Pietro Ferruzzi

Pietro Ferruzzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of TM9SF4 as a biomarker for tumor associated exosomes
    Publication number: 20220349892
    Abstract: The present invention relates to extracellular microvesicles biomarkers for determining the tumour transformation status or presence of a tumour in a subject, and to the uses of such biomarkers and to diagnostics methods using such biomarkers. In particular, the methods and uses of the invention involve isolation of TM9SF4-positive extracellular vesicles and detection of the expression of a second biomarker, preferably selected from the group consisting of CD9 protein, miR-21 and RNU6.
    Type: Application
    Filed: May 5, 2022
    Publication date: November 3, 2022
    Inventors: Francesco LOZUPONE, Antonio Chiesi, Paolo Guazzi, Natasa Zarovni, Pietro Ferruzzi, Davide Zocco
  • Use of TM9SF4 as a biomarker for tumor associated exosomes
    Publication number: 20170146543
    Abstract: The present invention relates to extracellular microvesicles biomarkers for determining the tumour transformation status or presence of a tumour in a subject, and to the uses of such biomarkers and to diagnostics methods using such biomarkers. In particular, the methods and uses of the invention involve isolation of TM9SF4-positive extracellular vesicles and detection of the expression of a second biomarker, preferably selected from the group consisting of CD9 protein, miR-21 and RNU6.
    Type: Application
    Filed: June 5, 2015
    Publication date: May 25, 2017
    Applicant: Exosomics Siena S.p.A.
    Inventors: Francesco LOZUPONE, Antonio Chiesi, Paolo Guazzi, Natasa Zarovni, Pietro Ferruzzi, Davide Zocco
  • Hedgehog pathway antagonists and therapeutic applications thereof
    Patent number: 8592463
    Abstract: Heterocyclic compounds that modulate the hedgehog signaling pathway, pharmaceutical composition thereof and their therapeutic applications.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: November 26, 2013
    Assignee: Siena Biotech S.p.A.
    Inventors: Russell John Thomas, Gal.la Pericot Mohr, Giacomo Minetto, Annette Cornelia Bakker, Pietro Ferruzzi
  • HEDGEHOG PATHWAY ANTAGONISTS AND THERAPEUTIC APPLICATIONS THEREOF
    Publication number: 20100286114
    Abstract: Heterocyclic compounds that modulate the hedgehog signaling pathway, pharmaceutical composition thereof and their therapeutic applications.
    Type: Application
    Filed: December 10, 2008
    Publication date: November 11, 2010
    Applicant: SIENA BIOTECH S.P.A.
    Inventors: Russell John Thomas, Gal.la Pericot Mohr, Giacomo Minetto, Annette Cornelia Bakker, Pietro Ferruzzi