Patents by Inventor Pietro M. Gullino

Pietro M. Gullino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Capillary cell culture device
    Patent number: 4220725
    Abstract: The growth of cells within a device containing a bundle of semi-permeable, tubular capillaries is disclosed. The bundle of capillaries is wrapped in an envelope of porous sheet material, thus creating an extra-envelope space into which the cells can migrate for periodic removal without disturbing the main culture within the capillaries. Porous capillaries may also be employed, in place of or in addition to the porous envelope.
    Type: Grant
    Filed: April 3, 1978
    Date of Patent: September 2, 1980
    Assignee: United States of America
    Inventors: Richard A. Knazek, Pietro M. Gullino
  • Method of simulation of lymphatic drainage utilizing a dual circuit, woven artificial capillary bundle
    Patent number: 4206015
    Abstract: A method for simulation of lymphatic drainage using artificial capillary cell culture device having two separate perfusion circuits, and with the ultrafiltration fibers of the two circuits being woven into a single bundle. The present device provides a matrix for high density growth of cultured cells in a continuous perfusion system. The device is particularly well adapted for the use of pressure differences between perfusion circuits.
    Type: Grant
    Filed: August 29, 1978
    Date of Patent: June 3, 1980
    Assignee: United States of America
    Inventors: Richard A. Knazek, Pietro M. Gullino, David S. Frankel
  • Method of cell culture using a dual circuit, woven artificial capillary bundle
    Patent number: 4200689
    Abstract: A method for cell culture using an artificial capillary cell culture device having two separate perfusion circuits, and with the ultrafiltration fibers of the two circuits being woven into a single bundle. The present device provides a maxtrix for high density growth of cultured cells in a continuous perfusion system. The device is particularly well adapted for the use of pressure differences between perfusion circuits,, such as in the simulation of lymphatic drainage.
    Type: Grant
    Filed: August 29, 1978
    Date of Patent: April 29, 1980
    Assignee: United States of America
    Inventors: Richard A. Knazek, Pietro M. Gullino, David S. Frankel
  • Dual circuit, woven artificial capillary bundle for cell culture
    Patent number: 4184922
    Abstract: An artificial capillary cell culture device having two separate perfusion circuits, and with the ultrafiltration fibers of the two circuits being woven into a single bundle, is disclosed. The present device provides a matrix for high density growth of cultured cells in a continuous perfusion system. The device is particularly well adapted for the use of pressure differences between perfusion circuits, such as in the simulation of lymphatic drainage.
    Type: Grant
    Filed: November 11, 1977
    Date of Patent: January 22, 1980
    Assignee: The Government of the United States
    Inventors: Richard A. Knazek, Pietro M. Gullino, David S. Frankel