Abstract: An aerosol-generating device is provided, including: a housing; a cavity configured to receive an aerosol-generating article; an aperture at least partially defined by the housing and being positioned at an end of the cavity and configured for insertion of the aerosol-generating article into the cavity through the aperture; a cover element configured to move with respect to the housing between a closed position in which the cover element at least partially covers the aperture and an open position in which the aperture is at least partially uncovered; and a sensor arranged to provide an electrical signal indicative of the position of the cover element with respect to the aperture. An aerosol-generating system including the aerosol-generating device and an aerosol-generating article including an aerosol-forming substrate is also provided.

Abstract: An aerosol-generating device is provided, including a housing; a cavity; an aperture at least partially defined by the housing and being positioned at an end of the cavity for insertion of the article into the cavity through the aperture; a cover element arranged for movement relative to the housing between a closed position partially covering the aperture and an open position partially uncovered; a sensor including a Hall effect sensor to provide an electrical signal indicative of a position of the cover element; an electrical heater to heat the article within the cavity and extending around an outer surface of an article received within the cavity; and an indicator element for movement relative to the sensor when moved between the closed and the open positions, the signal being determined by a position of the indicator element relative to the sensor, the indicator element including a magnetic material.

Abstract: An aerosol-generating device is provided, including: a housing; a cavity to receive an aerosol-generating article; an aperture at least partially defined by the housing and disposed at an end of the cavity for insertion of the article through the aperture; a cover element to move relative to the housing between a closed position and an open position; a sensor to provide an electrical signal indicative of a position of the cover element with respect to the aperture and including an optical sensor; and an indicator element to move relative to the sensor when the cover element is moved between the closed and the open positions and including an optical surface, the signal being determined by a position of the indicator element relative to the sensor, and the optical surface being configured to move relative to the optical sensor when the cover element moves between the closed and the open positions.

Abstract: An aerosol-generating device is provided, including a housing; a cavity; an aperture at least partially defined by the housing and being positioned at an end of the cavity for insertion of the article into the cavity through the aperture; a cover element arranged for movement relative to the housing between a closed position partially covering the aperture and an open position partially uncovered; a sensor including a Hall effect sensor to provide an electrical signal indicative of a position of the cover element; an electrical heater to heat the article within the cavity and extending around an outer surface of an article received within the cavity; and an indicator element for movement relative to the sensor when moved between the closed and the open positions, the signal being determined by a position of the indicator element relative to the sensor, the indicator element including a magnetic material.

Abstract: An aerosol-generating device is provided, including: a housing; a cavity to receive an aerosol-generating article; an aperture at least partially defined by the housing and disposed at an end of the cavity for insertion of the article through the aperture; a cover element to move, with respect to the housing, between a closed position and an open position; a sensor to provide an electrical signal indicative of a position of the cover element with respect to the aperture; an indicator element to move relative to the sensor and the cover element when the cover element is moved between the closed and the open positions, the signal being determined by a position of the indicator element relative to the sensor; and a mechanical linkage translating movement of the cover element between the closed and the open positions into movement of the indicator element with respect to the sensor.

Abstract: An aerosol-generating device is provided, including: a housing; a cavity to receive an aerosol-generating article; an aperture at least partially defined by the housing and disposed at an end of the cavity for insertion of the article through the aperture; a cover element to move relative to the housing between a closed position and an open position; a sensor to provide an electrical signal indicative of a position of the cover element with respect to the aperture and including an optical sensor; and an indicator element to move relative to the sensor when the cover element is moved between the closed and the open positions and including an optical surface, the signal being determined by a position of the indicator element relative to the sensor, and the optical surface being configured to move relative to the optical sensor when the cover element moves between the closed and the open positions.

Abstract: An aerosol-generating device is provided, including: a housing; a cavity to receive an aerosol-generating article; an aperture at least partially defined by the housing and disposed at an end of the cavity for insertion of the article through the aperture; a cover element to move, with respect to the housing, between a closed position and an open position; a sensor to provide an electrical signal indicative of a position of the cover element with respect to the aperture; an indicator element to move relative to the sensor and the cover element when the cover element is moved between the closed and the open positions, the signal being determined by a position of the indicator element relative to the sensor; and a mechanical linkage translating movement of the cover element between the closed and the open positions into movement of the indicator element with respect to the sensor.

Abstract: The present invention relates to new benzo-N-hydroxy amide compounds of formula (I) and pharmaceutically acceptable salts, isomers and prodrugs thereof, which show a significant inhibitory activity on the proliferation of tumor cells and specifically of cancer stem cells.

Abstract: The present invention relates to new benzo-N-hydroxy amide compounds of formula (I) and pharmaceutically acceptable salts, isomers and prodrugs thereof, which show a significant inhibitory activity on the proliferation of tumor cells and specifically of cancer stem cells.

Abstract: The use of derivatives of hydroxamic acid having histone deacetylase enzyme-inhibiting activity for the preparation of anti-inflammatory medicaments is disclosed.