Patents by Inventor Pietrzkowski Zbigniew

Pietrzkowski Zbigniew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme inhibitors and methods therefor
    Patent number: 6924269
    Abstract: An enzyme is inhibited by presenting the enzyme with a boron containing structure having a tetrahedral boron atom covalently bound to four ligands. Particularly preferred enzymes include prostaglandin endoperoxide synthase (COX-1 and COX-2), and particularly preferred structures include a ligand that confers at least 80-fold selectivity of COX-2 inhibition over COX-1 inhibition. Consequently, further methods are directed towards induction of apoptosis in a cell and methods of reducing pain.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: August 2, 2005
    Assignee: VDF Futureceuticals, Inc.
    Inventors: Dusan Miljkovic, Pietrzkowski Zbigniew
  • Enzyme inhibitors and methods therefor
    Publication number: 20040110724
    Abstract: An enzyme is inhibited by presenting the enzyme with a boron containing structure having a tetrahedral boron atom covalently bound to four ligands. Particularly preferred enzymes include prostaglandin endoperoxide synthase (COX-1 and COX-2), and particularly preferred structures include a ligand that confers at least 80-fold selectivity of COX-2 inhibition over COX-1 inhibition. Consequently, further methods are directed towards induction of apoptosis in a cell and methods of reducing pain.
    Type: Application
    Filed: December 4, 2002
    Publication date: June 10, 2004
    Inventors: Dusan Miljkovic, Pietrzkowski Zbigniew