Patents by Inventor Pijus Mandal

Pijus Mandal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PTPN11 inhibitors
    Patent number: 11945815
    Abstract: The present invention relates to compounds which are useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: April 2, 2024
    Inventors: Philip Jones, Barbara Czako, Christopher L Carroll, Pijus Mandal, Jason Cross
  • PTPN11 INHIBITORS
    Publication number: 20220041594
    Abstract: The present invention relates to compounds which are useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
    Type: Application
    Filed: July 20, 2021
    Publication date: February 10, 2022
    Inventors: Philip JONES, Barbara CZAKO, Christopher L. CARROLL, Pijus MANDAL, Jason CROSS
  • PTPN11 inhibitors
    Patent number: 11104675
    Abstract: The present invention relates to compounds which are useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: August 31, 2021
    Assignee: NAVIRE PHARMA, INC.
    Inventors: Philip Jones, Barbara Czako, Christopher L. Carroll, Pijus Mandal, Jason Cross
  • PTPN11 INHIBITORS
    Publication number: 20200048249
    Abstract: The present invention relates to compounds which are useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 13, 2020
    Inventors: Philip JONES, Barbara CZAKO, Christopher L. CARROLL, Pijus MANDAL, Jason CROSS
  • Inhibitors of signal transduction and activator of transcription 3
    Publication number: 20070010428
    Abstract: Stat3 inhibitor compounds are disclosed, wherein the compounds are structural analogs of Ac-pTyr-Leu-Pro-Gln-Thr-NH2 and bind to the SH2 domain of Stat3 under physiological conditions to inhibit a cellular signaling activity of Stat3.
    Type: Application
    Filed: September 2, 2005
    Publication date: January 11, 2007
    Inventors: John McMurray, Zhiyong Ren, David Coleman, Pijus Mandal, Xiaomin Chen, Warren Liao