Patents by Inventor Pik Kwan Lo

Pik Kwan Lo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11938187
    Abstract: The syntheses of two phosphoramidite building blocks based on BNSF and BNSMB structures are disclosed. Furthermore, some common molecular intermediates have been designed and linked to the central biphenyl core of the two molecules, resulting in a versatile and cost-effective design. These compounds can be effectively introduced to DNA oligonucleotides via the well-established standard cyanoethylphosphoramidite chemistry on the nucleic acid synthesizer. Fragmentation of these BNSF- and BNSMB-functionalized DNA strands is achieved by both one-photon and two-photon photolysis of photoliable bonds of [2-(2-nitrophenyl)propoxy]carbonyl groups on BNSF and BNSMB molecules respectively, resulting in two short pieces of single-stranded DNAs.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: March 26, 2024
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventors: Peggy Pik Kwan Lo, Ling Sum Liu, Dick Yan Tam
  • Publication number: 20230000983
    Abstract: The syntheses of two phosphoramidite building blocks based on BNSF and BNSMB structures are disclosed. Furthermore, some common molecular intermediates have been designed and linked to the central biphenyl core of the two molecules, resulting in a versatile and cost-effective design. These compounds can be effectively introduced to DNA oligonucleotides via the well-established standard cyanoethylphosphoramidite chemistry on the nucleic acid synthesizer. Fragmentation of these BNSF- and BNSMB-functionalized DNA strands is achieved by both one-photon and two-photon photolysis of photoliable bonds of [2-(2-nitrophenyl)propoxy]carbonyl groups on BNSF and BNSMB molecules respectively, resulting in two short pieces of single-stranded DNAs.
    Type: Application
    Filed: June 10, 2021
    Publication date: January 5, 2023
    Inventors: Peggy Pik Kwan LO, Ling Sum LIU, Dick Yan TAM
  • Patent number: 7822682
    Abstract: A system and method for processing particulars of a transaction over a network. The system comprises a supply chain tracking module for receiving supply chain event data from at least one supply chain monitor, the supply chain data relating to the condition or location of an item along a supply chain. The system also comprises a term and requirements module for receiving initial terms and requirements associated with the transaction and for generating modified terms and requirements based on supply chain event data and on at least one value algorithm, the modified terms and requirements being generated while the item is still in the supply chain.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: October 26, 2010
    Assignee: JPMorgan Chase Bank, N.A.
    Inventors: Brian L. Arnold, Paul H. Simpson, Thomas Steven Fitzgerald, Pik Kwan Lo, James K. Wilson, John C. Brockwell, Michael F. Quinn