Patents by Inventor Pilgrim Jackson

Pilgrim Jackson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PD-1 Binding Proteins and Methods of Use Thereof
    Publication number: 20230272076
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.
    Type: Application
    Filed: August 1, 2022
    Publication date: August 31, 2023
    Inventors: Brydon Bennett, Philip P. Chamberlain, Kandasamy Hariharan, Pilgrim Jackson, Marilyn Kehry, Roli Khattri, Monica Leung, Lisa Morrison, Jeonghoon Sun, Sanaa Torres, Henry H. Chan
  • CD47 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20210371522
    Abstract: CD47 antibodies that specifically inhibit the interaction between CD47 and the CD47-signal regulatory protein alpha (SIRP?) but not the interaction between CD47 and thrombospondin-1 (TSP-1), and methods of using these monoclonal antibodies as therapeutics are provided.
    Type: Application
    Filed: August 2, 2021
    Publication date: December 2, 2021
    Applicant: CELGENE CORPORATION
    Inventors: Victoria Sung, Pilgrim Jackson, Laure Escoubet, Kandasamy Hariharan, Michael Burgess, Kristen Hege, Heather Raymon, Piu Wong
  • PD-1 BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20200255525
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.
    Type: Application
    Filed: September 17, 2019
    Publication date: August 13, 2020
    Inventors: Brydon Bennett, Philip P. Chamberlain, Kandasamy Hariharan, Pilgrim Jackson, Marilyn Kehry, Roli Khattri, Monica Leung, Lisa Morrison, Jeonghoon Sun, Sanaa Torres, Henry H. Chan
  • CD47 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20200255515
    Abstract: Integrin-associated protein (IAP or CD47) antibodies that specifically inhibit the interaction between CD47 and the CD47-signal regulatory protein alpha (SIRPa) but not the interaction between CD47 and thrombospondin-1 (TSP-1), and methods of using these monoclonal antibodies as therapeutics are provided. Further disclosed are sequences of variable heavy chains and variable light chains of the antibodies provided.
    Type: Application
    Filed: May 9, 2017
    Publication date: August 13, 2020
    Inventors: Victoria Sung, Pilgrim Jackson, Laure Escoubet, Kandasamy Hariharan, Michael Burgess, Kristen Hege, Heather Raymon, Piu Wong
  • PD-1 binding proteins and methods of use thereof
    Patent number: 10428145
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: October 1, 2019
    Assignee: Celgene Corporation
    Inventors: Brydon Bennett, Philip Paul Chamberlain, Kandasamy Hariharan, Pilgrim Jackson, Marilyn Kehry, Roli Khattri, Monica Leung, Lisa Morrison, Jeonghoon Sun, Sanaa Torres, Henry H. Chan
  • USE OF BIOMARKERS FOR PREDICTING CLINICAL SENSITIVITY TO CANCER TREATMENT
    Publication number: 20180267043
    Abstract: A method of identifying a subject having cancer who is likely to be responsive to a treatment compound, comprising administering the treatment compound to a subject having cancer; obtaining a sample from the subject; determining the level of a biomarker in the sample from the subject; and diagnosing the subject as being likely to be responsive to the treatment compound if the level of the biomarker in the sample of the subject changes as compared to a reference level of the biomarker; wherein the treatment compound is a compound of Formula (I):
    Type: Application
    Filed: October 6, 2015
    Publication date: September 20, 2018
    Inventors: Antonia LOPEZ-GIRONA, Brian E. CATHERS, Gang LU, Pilgrim JACKSON, Hiroshi HANDA
  • METHODS FOR DETERMINING DRUG EFFICACY USING CEREBLON-ASSOCIATED PROTEINS
    Publication number: 20180209961
    Abstract: Use of cereblon-associated proteins as biomarkers for clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
    Type: Application
    Filed: November 15, 2017
    Publication date: July 26, 2018
    Inventors: Peter H. SCHAFER, Rajesh CHOPRA, Antonia LOPEZ-GIRONA, Laura CORRAL, Maria Yinglin WANG, Pilgrim JACKSON
  • Methods for determining drug efficacy using cereblon-associated proteins
    Patent number: 9857359
    Abstract: Use of cereblon-associated proteins as biomarkers for clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: January 2, 2018
    Assignee: CELGENE CORPORATION
    Inventors: Peter H. Schafer, Rajesh Chopra, Antonia Lopez-Girona, Laura Corral, Maria Yinglin Wang, Pilgrim Jackson
  • PD-1 BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20170088618
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.
    Type: Application
    Filed: September 28, 2016
    Publication date: March 30, 2017
    Inventors: Brydon Bennett, Philip Paul Chamberlain, Kandasamy Hariharan, Pilgrim Jackson, Marilyn Kehry, Roli Khattri, Monica Leung, Lisa Morrison, Jeonghoon Sun, Sanaa Torres, Henry H. Chan
  • METHODS FOR DETERMINING DRUG EFFICACY USING CEREBLON-ASSOCIATED PROTEINS
    Publication number: 20140162282
    Abstract: Use of cereblon-associated proteins as biomarkers for clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
    Type: Application
    Filed: June 28, 2013
    Publication date: June 12, 2014
    Applicant: CELGENE CORPORATION
    Inventors: Peter H. SCHAFER, Rajesh Chopra, Antonia Lopez-Girona, Laura Corral, Maria Yinglin Wang, Pilgrim Jackson