Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: The present invention relates to a novel pyrimidine derivative and a use thereof. The pyrimidine derivative has excellent MLK3 inhibitory activity and LRRK2 inhibitory activity and thus can be utilized in a pharmaceutical composition for preventing or treating cancers, virus infectious diseases, Parkinson's disease, nonalcoholic fatty liver disease, and tuberculosis.

Abstract: The present invention relates to a novel pyrimidine derivative and a use thereof. The pyrimidine derivative has excellent MLK3 inhibitory activity and LRRK2 inhibitory activity and thus can be utilized in a pharmaceutical composition for preventing or treating cancers, virus infectious diseases, Parkinson's disease, nonalcoholic fatty liver disease, and tuberculosis.

Abstract: A display device according to an embodiment includes a plurality of pixel blocks including a plurality of pixels connected to a plurality of scan lines and a plurality of data lines, respectively, and at least one active circuit; and a data driver supplying a data voltage to the plurality of data lines in a light emitting mode and supplying a neural network input signal to the plurality of data lines in an artificial neural network mode. In the artificial neural network mode, a scan signal is supplied to a scan line connected to at least one pixel block among the plurality of pixel blocks, and the neural network input signal is supplied to a data line connected to the at least one pixel block.

Abstract: The present invention relates to a novel indazole derivative, and a use thereof, wherein the indazole derivative has excellent TRIB2 or YAP inhibitory activity, and can be effectively used as a pharmaceutical composition for preventing or treating cancer, narcolepsy, and fasciitis.

Abstract: A display device according to an embodiment includes a plurality of pixel blocks including a plurality of pixels connected to a plurality of scan lines and a plurality of data lines, respectively, and at least one active circuit; and a data driver supplying a data voltage to the plurality of data lines in a light emitting mode and supplying a neural network input signal to the plurality of data lines in an artificial neural network mode. In the artificial neural network mode, a scan signal is supplied to a scan line connected to at least one pixel block among the plurality of pixel blocks, and the neural network input signal is supplied to a data line connected to the at least one pixel block.

Abstract: A thermoplastic resin composition of the present invention comprises: approximately 100 parts by weight of a polycarbonate resin; approximately 0.01-2 parts by weight of a modified aromatic vinyl-based copolymer resin; approximately 0.01-1 parts by weight of a metal aliphatic sulfonate; and approximately 0.01-2 parts by weight of a fluorinated olefin-based resin, wherein the modified aromatic vinyl-based copolymer resin is a polymer of a monomer mixture comprising an aromatic vinyl-based monomer and glycidyl (meth)acrylate. The thermoplastic resin composition has excellent flame retardancy, transparency and the like.

Abstract: The present disclosure relates to a novel piperidine-2,6-dione derivative and a use thereof and, more specifically, to a piperidine-2,6-dione derivative compound having a structure of a thalidomide analog. A compound of chemical formula 1 according to the present disclosure specifically binds with CRBN protein, and is involved in functions thereof. Therefore, the compound of the present disclosure can be favorably used in the prevention or treatment of leprosy, chronic graft versus host disease, an inflammatory disease, or cancer, which are caused by actions of CRBN protein.

Abstract: A thermoplastic resin composition of the present invention comprises: approximately 100 parts by weight of a polycarbonate resin; approximately 0.01-2 parts by weight of a modified aromatic vinyl-based copolymer resin; approximately 0.01-1 parts by weight of a metal aliphatic sulfonate; and approximately 0.01-2 parts by weight of a fluorinated olefin-based resin, wherein the modified aromatic vinyl-based copolymer resin is a polymer of a monomer mixture comprising an aromatic vinyl-based monomer and glycidyl (meth)acrylate. The thermoplastic resin composition has excellent flame retardancy, transparency and the like.

Abstract: A thermoplastic resin composition of the present invention contains: a polycarbonate resin; a siloxane copolymer comprising a repeat unit represented by chemical formula 1 and a repeat unit represented by chemical formula 2; a metal aromatic sulfonate; a fluorinated olefin-based resin; and an inorganic filler having a difference in refractive index with the polycarbonate resin of approximately 0-0.01. The thermoplastic resin composition has excellent flame retardancy, transparency, stiffness, heat resistance, balance of these physical properties, and the like.

Abstract: The present disclosure relates to a novel piperidine-2,6-dione derivative and a use thereof and, more specifically, to a piperidine-2,6-dione derivative compound having a structure of a thalidomide analog. A compound of chemical formula 1 according to the present disclosure specifically binds with CRBN protein, and is involved in functions thereof. Therefore, the compound of the present disclosure can be favorably used in the prevention or treatment of leprosy, chronic graft versus host disease, an inflammatory disease, or cancer, which are caused by actions of CRBN protein.

Abstract: A thermoplastic resin composition of the present invention contains: a polycarbonate resin; a siloxane copolymer comprising a repeat unit represented by chemical formula 1 and a repeat unit represented by chemical formula 2; a metal aromatic sulfonate; a fluorinated olefin-based resin; and an inorganic filler having a difference in refractive index with the polycarbonate resin of approximately 0-0.01. The thermoplastic resin composition has excellent flame retardancy, transparency, stiffness, heat resistance, balance of these physical properties, and the like.

Abstract: Disclosed are novel indanone derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The indanone derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

Abstract: A thermoplastic resin composition of the present invention comprises: about 100 parts by weight of a polycarbonate resin; about 10 to about 140 parts by weight of a (meth)acrylic-based resin which comprises a repeating unit represented by chemical formula 1; about 10 to about 80 parts by weight of an aromatic phosphate ester-based compound; and about 10 to 110 parts by weight of a glass fiber, wherein the difference in refractive index between the glass fiber and a resin mixture comprising the polycarbonate resin, the (meth)acrylic-based resin, and the aromatic phosphate ester-based compound is about 0.02 or less. The thermoplastic resin composition has excellent transparency and mechanical strength such as impact resistance, flexural modulus, etc.

Abstract: Disclosed are novel indanone derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The indanone derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

Abstract: Disclosed are indanone derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The indanone derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

Abstract: The polyester resin composition of the present invention is characterized by comprising: (A) 100 parts by weight of a high heat resistant polyester resin having a main chain formed by a structure derived from aromatic dicarboxylic acid and alicyclic diol, wherein the melting point of the high heat resistant polyester resin is 200° C. or more; (B) 0.1 to 80 parts by weight of white pigment; and (C) 1 to 40 parts by weight of polyolefin copolymer. The resin composition of the present invention further comprises 1 to 40 parts by weight of a high stiffness polyester resin having a main chain comprising a structure derived from aromatic dicarboxylic acid and aliphathic diol. The molding foam, which is obtained from the polyester resin composition and the manufactured polyester resin composition, has good flexibility, heat resistance, and yellowing resistance and can be used for an LED reflecting plate due to having improved impact strength.