Abstract: The present invention relates to the field of biomedicine, specifically to a monoclonal antibody targeting SIRP?, and a preparation method and the use thereof. The SIRP? antibody or the antigen-binding portion thereof prepared by the present invention has a high affinity for SIRP? and a low affinity for SIRP?, which differ by two orders of magnitude. The SIRP? antibody or the antigen-binding portion thereof can efficiently block the binding of CD47 to SIRP?-V1, SIRP?-V2 and SIRP?-V8, thereby promoting the activation of macrophages, particularly enhancing the regulatory antibody-dependent cellular phagocytosis (ADCP) of a target tumor cell, bridging about innate and adaptive immune responses, and promoting the synergistic anti-cancer effect of the SIRP? antibody or the antigen-binding portion thereof with a checkpoint inhibitor PD-(L)1 monoclonal antibody. The antibody can be used for treating various cancers and microbial infectious diseases.

Abstract: An ultrasound information processing system is disclosed in which ultrasound image data is packetized into ultrasound information packets and routed to one or more of a plurality of processors for performing image processing operations on the ultrasound image data, the ultrasound information packets being routed according to entries in a host-programmable routing table. A common distribution bus is coupled between packetizing circuitry and dedicated input buffers corresponding to each processor for distributing the ultrasound information packets, and a common output bus to is used to transfer processed image data from the processors to an output device. The disclosed ultrasound information processing system architecture allows for a high throughput rate for accommodating real-time image processing operations, while also allowing for ready programmability and upgradability.