Patents by Inventor Pina Cardarelli

Pina Cardarelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD-10 activated prodrug compounds
    Publication number: 20050267016
    Abstract: The compounds of the invention are modified forms of therapeutic agents. A typical prodrug compound of the invention comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the CD10 enzyme. Methods of treatment using the prodrug and methods of designing a prodrug are also disclosed.
    Type: Application
    Filed: December 22, 2004
    Publication date: December 1, 2005
    Applicant: MEDAREX, INC.
    Inventors: Christopher Bebbington, Matthew Nieder, Pina Cardarelli, Sanjeev Gangwar, Lesley Pickford, Chin Pan
  • Cyclic peptide inhibitors of .beta..sub.1 and .beta..sub.2 integrin-mediated adhesion
    Patent number: 5821329
    Abstract: The present invention describes cyclic peptide compounds which modulate integrin mediated adhesion. These compounds can inhibit both .beta..sub.1 and .beta..sub.2 mediated adhesion. The invention further relates to therapeutic uses for these compounds in the treatment of adhesion related pathologies.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: October 13, 1998
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Thomas J. Lobl, Shiu-Lan Chiang, Wolfgang Scholz, Nancy Delaet, Pina Cardarelli