Patents by Inventor Ping Bai
Ping Bai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11944384Abstract: The present application relates to computer-based preoperative planning technology, and discloses a preoperative planning method for multimodal ablation treatment and apparatus thereof, which can automatically provide objective, scientific, and quantitative multimodal ablation planning information. In this method, acquiring parameters of an volume to be ablated; calculating property changes of the tissue caused by performing freezing on the volume according to the parameters of the volume to be ablated, and acquiring a first planning data required for the property changes of the tissue to satisfy a first predetermined condition; further calculating property changes of the tissue caused by performing heating on the volume to acquire a second planning data required for the property changes of the tissue to satisfy a second predetermined condition based on the properties satisfying the first predetermined condition; outputting the first planning data and the second planning data.Type: GrantFiled: January 29, 2019Date of Patent: April 2, 2024Assignee: MAGI COMPANY LTD.Inventors: Xuemin Xu, Aili Zhang, Jianqi Sun, Ping Liu, Jingfeng Bai
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Publication number: 20240091172Abstract: A drug for antagonizing the replication of porcine reproductive and respiratory syndrome virus (PRRSV) and an application thereof. By using a viral infection test, a drug which antagonizes PRRSV—xanthohumol—is discovered for the first time from among a natural drug library of 386 plant sources. Xanthohumol can effectively inhibit PRRSV replication on both Marc-145 and PAM cells. Five xanthohumol derivatives having different molecular structures are artificially synthesized, and it is discovered that a derivative Xn-4 has the strongest inhibitory effect on virus replication in vitro. Test results of artificial infection and drug therapy in piglets show that the Xn-4 can effectively inhibit PRRSV viremia, relieve clinical symptoms of infected pigs, and significantly reduce lung inflammation and pathological damage.Type: ApplicationFiled: June 3, 2020Publication date: March 21, 2024Applicant: NANJING AGRICULTURAL UNIVERSITYInventors: Ping JIANG, Xuewei LIU, Juan BAI, Junren ZHANG, Xianwei WANG, Yufeng LI
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Publication number: 20240091766Abstract: Provided is a microfluidic device. The microfluidic device includes a first substrate and a second substrate disposed opposite to each other. A cavity is formed between the first substrate and the second substrate and configured to accommodate liquid. The first substrate includes multiple drive electrodes and multiple first electrodes, and the drive electrodes are disposed on a side of the first electrodes facing the second substrate. At least one of the drive electrodes includes at least one opening, and the at least one opening, along a direction perpendicular to a plane where the first substrate is located, penetrates the drive electrode where the at least one opening is located. An orthographic projection of at least one first electrode on the plane where the first substrate is located covers at least an orthographic projection of one opening on the plane where the first substrate is located.Type: ApplicationFiled: December 20, 2021Publication date: March 21, 2024Inventors: Kaidi ZHANG, Baiquan LIN, Kerui XI, Wei LI, Yunfei BAI, Ping SU
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Patent number: 10977133Abstract: Improved methods, systems and apparatus for storing and repairing multimedia files are provided that overcome the limitations of existing multimedia file repair technologies. Backup copies of the multimedia container information associated with given multimedia content data are stored, along with the multimedia content data, on an external storage detachably coupled to a recording device. A primary copy of the multimedia container information is stored on an internal storage associated with the recording device. The recording of the primary container information and the content data is performed in real-time or nearly real-time as the content data is captured by the recording device. In the case of an abnormal event (e.g., battery failure, disconnect of storage media), container information may be selected from the primary copy or the backup copies of the container information, thereby increasing the likelihood that the container file can be successfully repaired or regenerated.Type: GrantFiled: May 19, 2017Date of Patent: April 13, 2021Assignee: SZ DJI TECHNOLOGY CO., LTD.Inventors: Gao Ping Bai, Tai Wen Liang, Yuan Hua Zheng, Mingyu Wang
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Patent number: 10759757Abstract: A method of preparing a crystalline contrast agent for magnetic resonance imaging from a zwitterionic carboxylic pyridyl ligand includes mixing metal ion and the pyridyl ligand and obtaining crystals therefrom. The crystalline contrast agent includes a manganese-organic or gadolinium-organic 3D framework. The crystalline contrast agent is employed in a kit and a pharmaceutically acceptable composition. The method allows for preparing crystalline contrast agents with superior properties with easily available starting materials and with an economic and efficient process. The method allows for preparing crystalline contrast agents with exceptional water-stability and water-solubility, which exhibit high longitudinal relaxivities and with excellent stabilities under physiological conditions and low cytotoxicity. Further provided is a method for in vivo imaging of a subject, in particular a human, comprising administering the crystalline contrast agent to the subject.Type: GrantFiled: September 21, 2016Date of Patent: September 1, 2020Assignees: Macau University of Science and Technology, Southern Medical UniversityInventors: Jinxiang Chen, Jianxin Pang, Shuwen Liu, Li-Ping Bai, Zhi-Hong Jiang
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Patent number: 10618885Abstract: One embodiment provides a compound of Formula I that activates autophagy, a pharmaceutical composition and use thereof:Type: GrantFiled: January 3, 2018Date of Patent: April 14, 2020Inventors: Zhi-Hong Jiang, Li-Ping Bai, Xiaobo Zhou, Kam Wai Vincent Wong, Zhiyuan Zheng, Yuen Kwan Betty Law
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Patent number: 10519500Abstract: A method of preparing a crystalline copper-based coordination polymer comprises preparing a mixture of copper ions and a first quaternized carboxylate pyridyl ligand; adding a second polypyridyl ligand; and forming crystals of a copper-based coordination polymer therefrom. The crystalline copper-based coordination polymer is suitable for providing a sensing platform for detecting the presence of one or more target nucleic acid sequences such as viral RNA, in particular Dengue virus and/or Zika virus RNA with high selectivity and high specificity. A method of detecting at least a first target nucleic acid sequence, in particular from a viral RNA, in particular it is Flavivirus RNA, in a sample is also provided. Further provided is a kit including the crystalline copper-based coordination polymer and an oligonucleotide probe.Type: GrantFiled: May 22, 2017Date of Patent: December 31, 2019Assignees: MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY, SOUTHERN MEDICAL UNIVERSITYInventors: Jin-Xiang Chen, Bao-Ping Xie, Gui-Hua Qiu, Pei-Pei Hu, Zhen Liang, Ye-Mei Liang, Bin Sun, Li-Ping Bai, Zhi-Hong Jiang
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Publication number: 20190202802Abstract: One embodiment provides a compound of Formula I that activates autophagy, a pharmaceutical composition and use thereof:Type: ApplicationFiled: January 3, 2018Publication date: July 4, 2019Inventors: Zhi-Hong JIANG, Li-Ping BAI, Xiaobo ZHOU, Kam Wai Vincent WONG, Zhiyuan ZHENG, Yuen Kwan Betty LAW
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Patent number: 10260114Abstract: The present invention relates in a first aspect to a method of preparing a crystalline lanthanum-carboxylate coordination polymer and the crystalline lanthanum-carboxylate coordination polymer obtained or obtainable by the method. In another aspect of the present invention, also provides a method of detecting a target nucleic acid sequence in a sample.Type: GrantFiled: May 18, 2017Date of Patent: April 16, 2019Assignees: MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY, SOUTHERN MEDICAL UNIVERSITYInventors: Jin-Xiang Chen, Bin Sun, Bao-Ping Xie, Zhi-Hong Jiang, Li-Ping Bai
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Patent number: 10155721Abstract: One example embodiment is a lignanamide that includes a benzo-angular triquinane skeleton. The lignanamide is represented by formula (I) and any derivative of the formula (I), in which R is represented by —OH or —OCH3. Another example embodiment relates to a method of treating neurodegenerative disease by administering the lignanamide of the formula (I) to a person in need thereof.Type: GrantFiled: April 24, 2017Date of Patent: December 18, 2018Assignee: Macau University of Science and TechnologyInventors: Guo-Yuan Zhu, Zhi-Hong Jiang, Ji Yang, Xiao-Jun Yao, Xin Liu, Jing Fu, Li-Ping Bai, Liang Liu
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Publication number: 20180334733Abstract: The present invention relates in a first aspect to a method of preparing a crystalline lanthanum-carboxylate coordination polymer and the crystalline lanthanum-carboxylate coordination polymer obtained or obtainable by the method. In another aspect of the present invention, also provides a method of detecting a target nucleic acid sequence in a sample.Type: ApplicationFiled: May 18, 2017Publication date: November 22, 2018Inventors: JIN-XIANG CHEN, BIN SUN, BAO-PING XIE, ZHI-HONG JIANG, LI-PING BAI
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Publication number: 20180334713Abstract: A method of preparing a crystalline copper-based coordination polymer comprises preparing a mixture of copper ions and a first quaternized carboxylate pyridyl ligand; adding a second polypyridyl ligand; and forming crystals of a copper-based coordination polymer therefrom. The crystalline copper-based coordination polymer is suitable for providing a sensing platform for detecting the presence of one or more target nucleic acid sequences such as viral RNA, in particular Dengue virus and/or Zika virus RNA with high selectivity and high specificity. A method of detecting at least a first target nucleic acid sequence, in particular from a viral RNA, in particular it is Flavivirus RNA, in a sample is also provided. Further provided is a kit including the crystalline copper-based coordination polymer and an oligonucleotide probe.Type: ApplicationFiled: May 22, 2017Publication date: November 22, 2018Inventors: Jin-Xiang Chen, Bao-Ping Xie, Gui-Hua Qiu, Pei-Pei Hu, Zhen Liang, Ye-Mei Liang, Bin Sun, Li-Ping Bai, Zhi-Hong Jiang
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Publication number: 20180305300Abstract: One example embodiment is a lignanamide that includes a benzo-angular triquinane skeleton. The lignanamide is represented by formula (I) and any derivative of the formula (I), in which R is represented by —OH or —OCH3. Another example embodiment relates to a method of treating neurodegenerative disease by administering the lignanamide of the formula (I) to a person in need thereof.Type: ApplicationFiled: April 24, 2017Publication date: October 25, 2018Inventors: Guo-Yuan ZHU, Zhi-Hong JIANG, Ji YANG, Xiao-Jun YAO, Xin LIU, Jing FU, Li-Ping BAI, Liang LIU
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Patent number: 10023594Abstract: A method of preparing a crystalline zwitterionic zinc(II)-carboxylate compound includes the steps of preparing a mixture of zinc(II) ions and a first pyridyl ligand having three carboxylic acid moieties; subjecting the mixture to conditions under which a precipitate is formed; separating the precipitate; adding a solvent and optionally a second pyridyl ligand to the separated precipitate; subjecting the obtained mixture to conditions under which crystals of the zwitterionic zinc(II)-carboxylate compound are formed; and separating the crystals of the zwitterionic zinc(II)-carboxylate compound. Preferably but not exclusively, the crystalline zwitterionic zinc(II)-carboxylate compound essentially consists of at least one 1D coordination polymer.Type: GrantFiled: August 30, 2016Date of Patent: July 17, 2018Assignees: MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY, SOUTHERN MEDICAL UNIVERSITYInventors: Jin-Xiang Chen, Bin Sun, Hai-Qing Zhao, Bao-Ping Xie, Li-Ping Bai, Zhi-Hong Jiang
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Patent number: 9995749Abstract: There is method for detecting the presence or absence of a target analyte in a sample comprising the steps of: allowing an inorganic fluorescent particle to conjugate with a detection biomolecule that is bound to said target analyte, if present in said sample, said target analyte additionally being bound by a capture biomolecule immobilized on or within a nanostructure; and detecting the fluorescence emitted by said inorganic fluorescent particle, said nanostructure being capable of generating a surface plasmon resonance effect when excited by a light source to substantially increase the fluorescence emitted by said inorganic fluorescent particle, wherein the detected fluorescence indicates the presence of said target analyte in said sample.Type: GrantFiled: February 4, 2015Date of Patent: June 12, 2018Assignee: Agency for Science, Technology and ResearchInventors: Hong Yan Song, Ten It Wong, Anton Valentinovich Sadovoy, Xiaodong Zhou, Ping Bai, Lin Wu
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Publication number: 20180078660Abstract: A method of preparing a crystalline contrast agent for magnetic resonance imaging from a zwitterionic carboxylic pyridyl ligand includes mixing metal ion and the pyridyl ligand and obtaining crystals therefrom. The crystalline contrast agent includes a manganese-organic or gadolinium-organic 3D framework. The crystalline contrast agent is employed in a kit and a pharmaceutically acceptable composition. The method allows for preparing crystalline contrast agents with superior properties with easily available starting materials and with an economic and efficient process. The method allows for preparing crystalline contrast agents with exceptional water-stability and water-solubility, which exhibit high longitudinal relaxivities and with excellent stabilities under physiological conditions and low cytotoxicity. Further provided is a method for in vivo imaging of a subject, in particular a human, comprising administering the crystalline contrast agent to the subject.Type: ApplicationFiled: September 21, 2016Publication date: March 22, 2018Inventors: Jinxiang Chen, Jianxin Pang, Shuwen Liu, Li-Ping Bai, Zhi-Hong Jiang
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Publication number: 20180057512Abstract: A method of preparing a crystalline zwitterionic zinc(II)-carboxylate compound includes the steps of preparing a mixture of zinc(II) ions and a first pyridyl ligand having three carboxylic acid moieties; subjecting the mixture to conditions under which a precipitate is formed; separating the precipitate; adding a solvent and optionally a second pyridyl ligand to the separated precipitate; subjecting the obtained mixture to conditions under which crystals of the zwitterionic zinc(II)-carboxylate compound are formed; and separating the crystals of the zwitterionic zinc(II)-carboxylate compound. Preferably but not exclusively, the crystalline zwitterionic zinc(II)-carboxylate compound essentially consists of at least one 1D coordination polymer.Type: ApplicationFiled: August 30, 2016Publication date: March 1, 2018Inventors: Jin-Xiang Chen, Bin Sun, Hai-Qing Zhao, Bao-Ping Xie, Li-Ping Bai, Zhi-Hong Jiang
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Publication number: 20170262342Abstract: Improved methods, systems and apparatus for storing and repairing multimedia files are provided that overcome the limitations of existing multimedia file repair technologies. Backup copies of the multimedia container information associated with given multimedia content data are stored, along with the multimedia content data, on an external storage detachably coupled to a recording device. A primary copy of the multimedia container information is stored on an internal storage associated with the recording device. The recording of the primary container information and the content data is performed in real-time or nearly real-time as the content data is captured by the recording device. In the case of an abnormal event (e.g., battery failure, disconnect of storage media), container information may be selected from the primary copy or the backup copies of the container information, thereby increasing the likelihood that the container file can be successfully repaired or regenerated.Type: ApplicationFiled: May 19, 2017Publication date: September 14, 2017Inventors: Gao Ping Bai, Tai Wen Liang, Yuan Hua Zheng, Mingyu Wang
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Patent number: 9665444Abstract: Improved methods, systems and apparatus for storing and repairing multimedia files are provided that overcome the limitations of existing multimedia file repair technologies. Backup copies of the multimedia container information associated with given multimedia content data are stored, along with the multimedia content data, on an external storage detachably coupled to a recording device. A primary copy of the multimedia container information is stored on an internal storage associated with the recording device. The recording of the primary container information and the content data is performed in real-time or nearly real-time as the content data is captured by the recording device. In the case of an abnormal event (e.g., battery failure, disconnect of storage media), container information may be selected from the primary copy or the backup copies of the container information, thereby increasing the likelihood that the container file can be successfully repaired or regenerated.Type: GrantFiled: July 3, 2014Date of Patent: May 30, 2017Assignee: SZ DJI TECHNOLOGY CO., LTD.Inventors: Gao Ping Bai, Tai Wen Liang, Yuan Hua Zheng, Mingyu Wang
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Patent number: 9329339Abstract: A plasmonic detector and method for manufacturing a plasmonic detector. The plasmonic detector comprises two nanoscale metallic rods coupled to a bias voltage; a nanoscale cavity formed between adjacent ends of the two nanoscale metallic rods; and an absorption material disposed in the nanoscale cavity for converting an electromagnetic field to an electric current for outputting via the nanoscale metallic rods.Type: GrantFiled: September 2, 2010Date of Patent: May 3, 2016Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Ping Bai, Mingxia Gu, Erping Li