Patents by Inventor Ping BU

Ping BU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfuryl-substituted benzoheterocyclic derivative, preparation method and medical use thereof
    Patent number: 10793549
    Abstract: The present invention relates to a sulfuryl-substituted benzoheterocyclic derivative, a preparation method and medical use thereof. Particularly, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, and a preparation method and application thereof. The definition of each group in the formula can be found in the specification and the claims.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: October 6, 2020
    Assignees: SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD., YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yunzhou Jin, Xiang Chen, Pengfei Cheng, Ping Bu, Leitao Zhang, Chong Wen, Yingtao Liu, Fusheng Zhou, Ming Weng, Jiong Lan
  • 1,5,7-TRISUBSTITUTED ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES
    Publication number: 20200262813
    Abstract: The present disclosure relates to 1,5,7-trisubstituted isoquinoline derivatives, their preparation and pharmaceutical use. In particular, the present disclosure discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof. The definitions of the groups in the formula can be found in the specification and claims.
    Type: Application
    Filed: November 10, 2017
    Publication date: August 20, 2020
    Inventors: Fusheng ZHOU, Xiaoyong SHI, Lixiao WANG, Feng XU, Jing XIE, Ping BU, Pengfei CHENG, Zhiyuan ZHANG, Nanping CAI, Jiong LAN
  • SULFONYL-SUBSTITUTED BENZOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD AND MEDICAL USE THEREOF
    Publication number: 20190300506
    Abstract: The present invention relates to a sulfonyl-substituted benzoheterocyclic derivative, a preparation method and medical use thereof. Particularly, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, and a preparation method and application thereof. The definition of each group in the formula can be found in the specification and the claims.
    Type: Application
    Filed: November 10, 2017
    Publication date: October 3, 2019
    Inventors: Yunzhou JIN, Xiang CHEN, Pengfei CHENG, Ping BU, Leitao ZHANG, Chong WEN, Yingtao LIU, Fusheng ZHOU, Ming WENG, Jiong LAN
  • Azabicyclo derivatives, process for preparation thereof and medical use thereof
    Patent number: 10085983
    Abstract: Azabicyclo derivatives, a preparation process, and medical use thereof are provided. In particular, azabicyclo derivatives of formula (I), pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs thereof are described. The azabicyclo derivatives of formula (I) are useful as Epidermal Growth Factor Receptor (EGFR) inhibitors. The definitions of the variable R groups in the azabicyclo derivatives of formula (I) are described in the specification.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: October 2, 2018
    Assignees: Shanghai Haiyan Pharmaceutical Technology Co., Ltd., Yangtze River Pharmaceutical Group Co., Ltd.
    Inventors: Yunzhou Jin, Ping Bu, Qi He, Jiong Lan, Fusheng Zhou, Liang Zhang, Xiangyu He
  • AZABICYCLO DERIVATIVES, PROCESS FOR PREPARATION THEROF AND MEDICAL USE THEREOF
    Publication number: 20170296537
    Abstract: Azabicyclo derivatives, a preparation process, and medical use thereof are provided. In particular, azabicyclo derivatives of formula (I), pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs thereof are described. The azabicyclo derivatives of formula (I) are useful as Epidermal Growth Factor Receptor (EGFR) inhibitors. The definitions of the variable R groups in the azabicyclo derviatives of formula (I) are described in the specification.
    Type: Application
    Filed: September 24, 2015
    Publication date: October 19, 2017
    Inventors: Yunzhou JIN, Ping BU, Qi HE, Jiong LAN, Fusheng ZHOU, Liang ZHANG, Xiangyu HE
  • Virus induced gene silencing (VIGS) for functional analysis of genes in cotton
    Patent number: 8853493
    Abstract: The invention relates to the functional analysis of genes in cotton by employing the Virus Induced Gene Silencing (VIGS) method. More specifically this method induces gene silencing in cotton with the help of the Tobacco Rattle Virus (TRV) vectors RNA1 and RNA2 and phenotypic effects on the cotton plant can be analysed Moreover this invention also provides transient expression vector TRV RNA2 in order to transiently express genes in cotton plants and plant tissue under the influence of a strong subgenomic promoter.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: October 7, 2014
    Assignee: Temasek Life Sciences Laboratory Limited
    Inventors: Jian Ye, Nam Hai Chua, Jing Qu, Yun Feng Geng, Yun Ping Bu
  • VIRUS INDUCED GENE SILENCING (VIGS) FOR FUNCTIONAL ANALYSIS OF GENES IN COTTON
    Publication number: 20120096595
    Abstract: The invention relates to the functional analysis of genes in cotton by employing the Virus Induced Gene Silencing (VIGS) method. More specifically this method induces gene silencing in cotton with the help of the Tobacco Rattle Virus (TRV) vectors RNA1 and RNA2 and phenotypic effects on the cotton plant can be analysed Moreover this invention also provides transient expression vector TRV RNA2 in order to transiently express genes in cotton plants and plant tissue under the influence of a strong subgenomic promoter.
    Type: Application
    Filed: June 10, 2010
    Publication date: April 19, 2012
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Jian Ye, Nam Hai Chua, Jing Qu, Yun Feng Geng, Yun Ping Bu